Farokh Dotiwala

Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination.

The yeast DNA damage checkpoint proteins control a cytoplasmic response to DNA damage.

Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals.

Mad2 prolongs DNA damage checkpoint arrest caused by a double-strand break via a centromere-dependent mechanism.

DNA damage checkpoint triggers autophagy to regulate the initiation of anaphase.

Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach.

Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes.