Dominik Paquet

Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin.

A zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluation.

Transgenic zebrafish as a novel animal model to study tauopathies and other neurodegenerative disorders in vivo.

Methylene blue fails to inhibit Tau and polyglutamine protein dependent toxicity in zebrafish.

Parkin is protective against proteotoxic stress in a transgenic zebrafish model.

In vivo imaging of disease-related mitochondrial dynamics in a vertebrate model system.

Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy.

In vivo imaging of mitochondria in intact zebrafish larvae.