polydimethylsiloxane-polycarbonate-microfluidic-devices-for-cell

Polydimethylsiloxane-polycarbonate Microfluidic Devices for Cell Migration Studies Under Perpendicular Chemical and Oxygen Gradients

This paper reports a microfluidic device made of polydimethylsiloxane (PDMS) with an embedded polycarbonate (PC) thin film to study cell migration under ...

Academia Sinica

This paper presents results on the numerical and experimental studies of focusing and waveguiding of the lowest anti-symmetric Lamb wave in micro-fabricated piezoelectric phononic plates. The phononic structure was based on an AT-cut quartz plate and consisted of a gradient-index phononic crystal (GRIN PC) lens and a linear phononic plate waveguide. The band structures of the square-latticed AT-cut quartz phononic crystal plates with different filling ratios were analyzed using the finite element method. The design of a GRIN PC plate lens which is attached with a linear phononic plate waveguide is proposed. In designing the waveguide, propagation modes in square-latticed PC plates with different waveguide widths were studied and the results were served for the experimental design. In the micro-fabrication, deep reactive ion etching (Deep-RIE) process with a laboratory-made etcher was utilized to fabricate both the GRIN PC plate lens and the linear phononic waveguide on an 80 μm thick AT-cut quartz plate. Interdigital transducers were fabricated directly on the quartz plate to generate the lowest anti-symmetric Lamb waves. A vibro-meter was used to detect the wave fields and the measured results on the focusing and waveguiding of the piezoelectric GRIN PC lens and waveguide are in good accordance with the numerical predictions. The results of this study may serve as a basis for developing an active micro plate lens and related devices.

Focusing and waveguiding of Lamb waves in micro-fabricated piezoelectric phononic plates.

This paper presents numerical and experimental results on the level repulsion of gigahertz surface acoustic waves in an air/ST-cut quartz phononic structure with finite-depth holes. The colorful dispersion with the parameter of the in-plane (sagittal plane) ratio of polarization was adopted to determine the Rayleigh wave bandgap induced by the level repulsion. The results of numerical analyses showed that the frequency and width of the bandgap induced by the level repulsion strongly depend on the geometry of the air holes in the phononic structure. In the experiment, a pair of slanted interdigital transducers with frequency in the gigahertz range was designed and fabricated to generate and receive broadband Rayleigh waves, whereas the reactive ion etching process with electron-beam lithography was used to fabricate submicrometer phononic structures. The measured results of the bandgap induced by the level repulsion agreed favorably with the numerical prediction.

Sih-Ling Yeh

Research Center for Applied Sciences

Academia Sinica

Polydimethylsiloxane-polycarbonate Microfluidic Devices for Cell Migration Studies Under Perpendicular Chemical and Oxygen Gradients

Sih-Ling Yeh

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Research Center for Applied Sciences

Academia Sinica

Polydimethylsiloxane-polycarbonate Microfluidic Devices for Cell Migration Studies Under Perpendicular Chemical and Oxygen Gradients

Research Center for Applied Sciences