Fuminori Tsuruta

The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria.

JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins.

JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3.

The C terminus of the L-type voltage-gated calcium channel Ca(V)1.2 encodes a transcription factor.

PIKfyve regulates CaV1.2 degradation and prevents excitotoxic cell death.

The carboxy-terminal fragment of alpha(1A) calcium channel preferentially aggregates in the cytoplasm of human spinocerebellar ataxia type 6 Purkinje cells.

Ubiquitin ligase activity of Cul3-KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutation.

Cytoplasmic location of α1A voltage-gated calcium channel C-terminal fragment (Cav2.1-CTF) aggregate is sufficient to cause cell death.

Brap2 regulates temporal control of NF-κB localization mediated by inflammatory response.

Competition between α-actinin and Ca²⁺-calmodulin controls surface retention of the L-type Ca²⁺ channel Ca(V)1.2.

Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis.

Myeloma overexpressed 2 (Myeov2) regulates L11 subnuclear localization through Nedd8 modification.

PIKfyve mediates the motility of late endosomes and lysosomes in neuronal dendrites.

CACUL1/CAC1 Regulates the Antioxidant Response by Stabilizing Nrf2.

KIAA0368-deficiency affects disassembly of 26S proteasome under oxidative stress condition.

New insights into the functions of PtdIns(3,5)P2 in the pathogenisis of neurodegenerative disorders.

SCFFbl12 Increases p21Waf1/Cip1 Expression Level through Atypical Ubiquitin Chain Synthesis.

USP15 stabilizes the transcription factor Nrf1 in the nucleus, promoting the proteasome gene expression.

CACUL1/CAC1 attenuates p53 activity through PML post-translational modification.