Chemical Biology and Therapeutics
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Comparison of compound administration methods in biochemical assays: effects on apparent compound potency using either assay-ready compound plates or pin tool-delivered compounds.
Journal of biomolecular screening Jan, 2013 | Pubmed ID: 22904199
A homogeneous, high-throughput assay for phosphatidylinositol 5-phosphate 4-kinase with a novel, rapid substrate preparation.
PloS one , 2013 | Pubmed ID: 23326584
Bioluminescent assays for cytochrome P450 enzymes.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23475663
Application of Titration-Based Screening for the Rapid Pilot Testing of High-Throughput Assays.
Journal of biomolecular screening Jun, 2014 | Pubmed ID: 24246376
Biochemical, cellular, and biophysical characterization of a potent inhibitor of mutant isocitrate dehydrogenase IDH1.
The Journal of biological chemistry May, 2014 | Pubmed ID: 24668804
Composition and applications of focus libraries to phenotypic assays.
Frontiers in pharmacology , 2014 | Pubmed ID: 25104937
Variomics screen identifies the re-entrant loop of the calcium-activated chloride channel ANO1 that facilitates channel activation.
The Journal of biological chemistry Jan, 2015 | Pubmed ID: 25425649
Bioluminescence Methods for Assaying Kinases in Quantitative High-Throughput Screening (qHTS) Format Applied to Yes1 Tyrosine Kinase, Glucokinase, and PI5P4Kα Lipid Kinase.
Methods in molecular biology (Clifton, N.J.) , 2016 | Pubmed ID: 26501901
Characterization and Use of TurboLuc Luciferase as a Reporter for High-Throughput Assays.
Biochemistry Aug, 2018 | Pubmed ID: 29641191
Novartis Institutes for BioMedical Research
Lesley Mathews Griner1,
Kalyani Gampa1,
Toan Do2,
Huyen Nguyen2,
David Farley2,
Christopher J. Hogan2,
Douglas S. Auld2,
Serena J. Silver1
1Oncology Drug Discovery: Molecular Pharmacology, Novartis Institutes for Biomedical Research,
2Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research
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