Enrique Saez

TLE3 is a dual-function transcriptional coregulator of adipogenesis.

Application of activity-based protein profiling to study enzyme function in adipocytes.

Activating PI3-kinase to dampen inflammation.

ThermoMouse: an in vivo model to identify modulators of UCP1 expression in brown adipose tissue.

Ligand and Target Discovery by Fragment-Based Screening in Human Cells.

Intestinal bitter taste receptor activation alters hormone secretion and imparts metabolic benefits.

PGRMC2 is an intracellular haem chaperone critical for adipocyte function.

Discovery of small-molecule enzyme activators by activity-based protein profiling.