fibroblast-derived-human-engineered-connective-tissue-for-screening

Fibroblast Derived Human Engineered Connective Tissue for Screening Applications

Fibroblasts are phenotypically highly dynamic cells, which quickly transdifferentiate into myofibroblasts in response to biochemical and biomechanical ...

DZHK (German Center for Cardiovascular Research) partner site, Goettingen

University Medical Center Goettingen

Advancing structural and functional maturation of stem cell-derived cardiomyocytes remains a key challenge for applications in disease modeling, drug screening, and heart repair. Here, we sought to advance cardiomyocyte maturation in engineered human myocardium (EHM) toward an adult phenotype under defined conditions.

Article	Year
Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair. Circulation\| PubMed ID: 28167635	2017
Physics meets medicine - At the heart of active matter. Progress in biophysics and molecular biology\| PubMed ID: 30980833	2019

Tim Meyer

Biography

JoVE Journal Publications

Other Publications