Kaitlyn Knutson

Mechanosensitive ion channel Piezo2 is important for enterochromaffin cell response to mechanical forces.

Mechanosensitive ion channel Piezo2 is inhibited by D-GsMTx4.

Sodium channel Na1.3 is important for enterochromaffin cell excitability and serotonin release.

A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release.

Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing.

A simple automated approach to measure mouse whole gut transit.

Specialized Mechanosensory Epithelial Cells in Mouse Gut Intrinsic Tactile Sensitivity.