Yoshinori Tanaka

Kinase activity-tagged western blotting assay.

Convulsive responses to seizure-inducible drugs are exacerbated in progranulin-deficient mice.

Possible roles of N- and C-terminal unstructured tails of CPI-17 in regulating Ca sensitization force of smooth muscle.

Overexpression of progranulin increases pathological protein accumulation by suppressing autophagic flux.

Abemaciclib and Vacuolin-1 induce vacuole-like autolysosome formation - A new tool to study autophagosome-lysosome fusion.

Dysregulation of the progranulin-driven autophagy-lysosomal pathway mediates secretion of the nuclear protein TDP-43.

PHI-1, an Endogenous Inhibitor Protein for Protein Phosphatase-1 and a Pan-Cancer Marker, Regulates Raf-1 Proteostasis.

Abemaciclib and Vacuolin-1 decrease aggregate-prone TDP-43 accumulation by accelerating autophagic flux.