Lu Tang

Novel approach reveals genomic landscapes of single-strand DNA breaks with nucleotide resolution in human cells.

A CRISPR/Cas13-based approach demonstrates biological relevance of vlinc class of long non-coding RNAs in anticancer drug response.

Very long intergenic non-coding (vlinc) RNAs directly regulate multiple genes in cis and trans.

Hotspots of single-strand DNA "breakome" are enriched at transcriptional start sites of genes.

Complexities of mammalian transcriptome revealed by targeted RNA enrichment techniques.

Dynamic Patterns of Mammalian Mitochondrial DNA Replication Uncovered Using SSiNGLe-5'ES.

Genome-Wide Profiling of Endogenous Single-Stranded DNA Using the SSiNGLe-P1 Method.

Evidence for widespread existence of functional novel and non-canonical human transcripts.

A novel human protein-coding locus identified using a targeted RNA enrichment technique.