Burkhard Wiesner

Fluorescence spectroscopic quantification of the release of cyclic nucleotides from photocleavable [bis(carboxymethoxy)coumarin-4-yl]methyl esters inside cells.

Intracellular calcium measurements of single human skin cells after stimulation with corticotropin-releasing factor and urocortin using confocal laser scanning microscopy.

DMACM-caged adenosine nucleotides: ultrafast phototriggers for ATP, ADP, and AMP activated by long-wavelength irradiation.

[7-(Dialkylamino)coumarin-4-yl]methyl-Caged Compounds as Ultrafast and Effective Long-Wavelength Phototriggers of 8-Bromo-Substituted Cyclic Nucleotides.

The prostaglandin E2 analogue sulprostone antagonizes vasopressin-induced antidiuresis through activation of Rho.

DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1.

Aquaporin-1, nothing but a water channel.

Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells.

c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis.

Enhancement of intracellular concentration and biological activity of PNA after conjugation with a cell-penetrating synthetic model peptide.

Pharmacochaperones post-translationally enhance cell surface expression by increasing conformational stability of wild-type and mutant vasopressin V2 receptors.

Studies on the cellular uptake of substance P and lysine-rich, KLA-derived model peptides.

(Coumarin-4-yl)methyl esters as highly efficient, ultrafast phototriggers for protons and their application to acidifying membrane surfaces.

Live cell imaging of G protein-coupled receptors.

Nuclear export determines the cytokine sensitivity of STAT transcription factors.

Coumarinylmethyl esters for ultrafast release of high concentrations of cyclic nucleotides upon one- and two-photon photolysis.

Dimerization of corticotropin-releasing factor receptor type 1 is not coupled to ligand binding.

Spatial organisation of AKAP18 and PDE4 isoforms in renal collecting duct principal cells.

The corticotropin-releasing factor receptor type 2a contains an N-terminal pseudo signal peptide.

TIRC7 inhibits T cell proliferation by modulation of CTLA-4 expression.

Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells.

A Role of myosin Vb and Rab11-FIP2 in the aquaporin-2 shuttle.

Increase in fluidity in the membrane of MT3 breast cancer cells correlates with enhanced cell adhesion in vitro and increased lung metastasis in NOD/SCID mice.

Rescue of a nephrogenic diabetes insipidus-causing vasopressin V2 receptor mutant by cell-penetrating peptides.

Microtubules are needed for the perinuclear positioning of aquaporin-2 after its endocytic retrieval in renal principal cells.

Formation of tight junction: determinants of homophilic interaction between classic claudins.

AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulum.

{7-[Bis(carboxymethyl)amino]coumarin-4-yl}methoxycarbonyl derivatives for photorelease of carboxylic acids, alcohols/phenols, thioalcohols/thiophenols, and amines.

Derlin-1 and p97/valosin-containing protein mediate the endoplasmic reticulum-associated degradation of human V2 vasopressin receptors.

Nuclear localization of the zebrafish tight junction protein nagie oko.

Interaction of angiotensin-converting enzyme (ACE) with membrane-bound carboxypeptidase M (CPM) - a new function of ACE.

Use of Kaede fusions to visualize recycling of G protein-coupled receptors.

Apical membrane maturation and cellular rosette formation during morphogenesis of the zebrafish lateral line.

Caged progesterone: a new tool for studying rapid nongenomic actions of progesterone.

Cellular uptake and biological activity of peptide nucleic acids conjugated with peptides with and without cell-penetrating ability.

Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein.

Impact of membrane properties on uptake and transcytosis of colloidal nanocarriers across an epithelial cell barrier model.

The pseudo signal peptide of the corticotropin-releasing factor receptor type 2a decreases receptor expression and prevents Gi-mediated inhibition of adenylyl cyclase activity.

Reciprocal regulation of aquaporin-2 abundance and degradation by protein kinase A and p38-MAP kinase.

Structural basis of oligomerization in septin-like GTPase of immunity-associated protein 2 (GIMAP2).

Routes of epithelial water flow: aquaporins versus cotransporters.

Photocontrol of contracting muscle fibers.

Inhibition of biosynthesis of human endothelin B receptor by the cyclodepsipeptide cotransin.

Growth factor- and adhesion protein-like components of fetal calf serum can significantly enhance the intracellular delivery of Peptide nucleic acids.

Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease.

New pathogenic thyrotropin receptor mutations decipher differentiated activity switching at a conserved helix 6 motif of family A GPCR.

Use of Kikume green-red fusions to study the influence of pharmacological chaperones on trafficking of G protein-coupled receptors.

Xirp proteins mark injured skeletal muscle in zebrafish.

Live cell imaging of G protein-coupled receptors.

Coumarin-based octopamine phototriggers and their effects on an insect octopamine receptor.

The Pseudo signal peptide of the corticotropin-releasing factor receptor type 2A prevents receptor oligomerization.

Multivalent design of apoptosis-inducing bid-BH3 peptide-oligosaccharides boosts the intracellular activity at identical overall peptide concentrations.

Structural insights into the mechanism of GTPase activation in the GIMAP family.

Small-molecule screening identifies modulators of aquaporin-2 trafficking.