Applied Medical

1 ARTICLES PUBLISHED IN JoVE

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Medicine

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats
John R. Wagner 1, Takashi Taguchi 1, Jane Y. Cho 2, Chandrashekhar Charavaryamath 3, Dominique J. Griffon 1
1College of Veterinary Medicine, Western University of Health Sciences, 2Applied Medical, 3College of Veterinary Medicine, Iowa State University

This paper describes the preparation and evaluation of umbilical cord matrix-derived mesenchymal stem cells spheroids with a bilateral patellar tendon defect model in a rat. This model was associated with an acceptable morbidity and was found to detect differences between untreated and treated tendons, and between the two treatments tested.

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