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Chapter 29

Cell-Cell Interactions

Cell Adhesion Molecules - Types and Functions
Cell Adhesion Molecules - Types and Functions
Cell adhesion molecules (CAMs) are pivotal to multicellularity and the coordinated functioning of tissues and organ systems. They enable physical ...
Structure of Cadherins
Structure of Cadherins
The cadherins were one of the first cell adhesion molecules discovered; the term “cadherins”   is based on their calcium-dependent ...
Cadherins in Tissue Organization
Cadherins in Tissue Organization
The cadherins are a superfamily of cell adhesion molecules comprising over 180 variants, with specific tissues expressing a particular combination of ...
Catenins
Catenins
Catenins are characterized by multiple binding domains and dynamic structures that allow them to function as linker proteins in cell junction complexes. ...
Selectins
Selectins
Cell adhesion is  an essential aspect of multicellularity. While stable cell interactions usually occur between cells of the same type, transient ...
Immunoglobulin-like Cell Adhesion Molecules
Immunoglobulin-like Cell Adhesion Molecules
Immunoglobulin-like cell adhesion molecules or Ig-CAMs are a versatile group of cell surface glycoproteins belonging to the immunoglobulin protein ...
Overview of Cell-Cell Junctions
Overview of Cell-Cell Junctions
The complex three-dimensional arrangement of cells in any multicellular organism is defined and maintained by interactions of cells with each other and ...
Adherens Junctions
Adherens Junctions
Strong contact points between adjacent cells anchor them to each other, forming tissues. Such anchoring junctions are of two types –  adherens ...
Tension Response at Adherens Junctions
Tension Response at Adherens Junctions
The adherens junctions that anchor cells together are multi-protein complexes that dynamically adapt to mechanical stimuli such as tensile forces and ...
Desmosomes
Desmosomes
The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed ...
Tight Junctions
Tight Junctions
Tight junctions are molecular seals between cells that prevent the leaking of fluids, ions, and other small solutes across cavities and compartments in ...
Gap Junctions
Gap Junctions
The cytoplasm of adjacent animal cells can exchange small molecules, ions, and secondary messengers via the communication channels which form the gap ...
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