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Chapter 30

Cell Polarization and Migration

Cell Migration
Cell Migration
Cell migration is a process by which the cells move from one location to another, playing an essential role in embryological development, repair and ...
Actin Polymerization and Cell Motility
Actin Polymerization and Cell Motility
Actin is a family of globular proteins that are highly abundant in eukaryotic cells. It makes up approximately 1-5% of total cell protein concentration. ...
Types of Membrane Protrusions
Types of Membrane Protrusions
The protrusion of the cell surface is an initial step for several cellular processes, including cell migration, phagocytosis, and neurite outgrowth. These ...
Mechanism of Lamellipodia Formation
Mechanism of Lamellipodia Formation
Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or ...
Mechanism of Filopodia Formation
Mechanism of Filopodia Formation
Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, ...
Cancer Cell Migration through Invadopodia
Cancer Cell Migration through Invadopodia
Invadosome is a broad category of cell surface structures with proteolytic activity that  degrades the extracellular matrix (ECM). Invadosomes are ...
Cell Motility through Blebbing
Cell Motility through Blebbing
Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including ...
Role of Myosin in Cell Migration
Role of Myosin in Cell Migration
Myosins are multimeric motor proteins involved in various cellular processes such as migration, adhesion, and proliferation. Myosin II is the most common ...
Cell Polarization by Rho Proteins
Cell Polarization by Rho Proteins
Cell polarity is the asymmetric distribution of cellular and membrane components, making one side of the cell different from the other. This polarity is ...
Chemotaxis and Direction of Cell Migration
Chemotaxis and Direction of Cell Migration
Cells can detect chemical cues in their environment and reorganize the cytoskeleton to migrate toward them or away from them. This directional migration, ...
Cytoskeletal Coordination in Cell Migration
Cytoskeletal Coordination in Cell Migration
A migrating cell changes its shape during the cyclic events of attachment and detachment from the substratum and repositions the cell organelles ...
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