The filtration membrane in the renal system is a highly specialized structure essential for filtering blood. It consists of glomerular capillaries and podocytes, forming a selective barrier that permits the passage of water and small solutes while restricting most plasma proteins and blood cells.
Components of the Filtration Membrane
The filtration process involves three key layers: the glomerular endothelial cells, the basement membrane, and the podocyte-formed filtration slits.
Functionality of the Filtration Membrane
The filtration membrane's design ensures selective permeability, allowing the kidneys to efficiently filter blood while retaining essential proteins and cells. Its combination of physical and charge-based filtration mechanisms prevents the loss of large molecules and cellular components, enabling effective waste removal and fluid regulation.
From Chapter 29:
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