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Encyclopedia of Experiments

A Mouse Tail Snip Procedure for Peripheral Blood Collection and Plasma Isolation

In this video, we demonstrate a tail-snipping procedure in a mouse model to collect peripheral blood. The collected blood is subsequently subjected to centrifugation to separate plasma, which can be used for further experiments.

All procedures involving animal models have been reviewed by the local institutional animal care committee and the JoVE veterinary review board.

1. Serial Blood Collection and Plasma Monitoring for Exogenous Human Cytokine in Mice

  1. Blood collection via tail snip
    1. Disinfect the biosafety hood and assemble the mouse restrainer, scissors, and other tools/supplies for the procedure.
    2. Place the mouse in a re.......

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