Eric Ghigo

Survival of Tropheryma whipplei, the agent of Whipple's disease, requires phagosome acidification.

Conventional mechanical ventilation of healthy lungs induced pro-inflammatory cytokine gene transcription.

Coxiella burnetii survival in THP-1 monocytes involves the impairment of phagosome maturation: IFN-gamma mediates its restoration and bacterial killing.

IFN-gamma-induced apoptosis and microbicidal activity in monocytes harboring the intracellular bacterium Coxiella burnetii require membrane TNF and homotypic cell adherence.

Dysregulation of cytokines in acute Q fever: role of interleukin-10 and tumor necrosis factor in chronic evolution of Q fever.

Interleukin-4 induces Coxiella burnetii replication in human monocytes but not in macrophages.

Lipopolysaccharide from Coxiella burnetii is involved in bacterial phagocytosis, filamentous actin reorganization, and inflammatory responses through Toll-like receptor 4.

Link between impaired maturation of phagosomes and defective Coxiella burnetii killing in patients with chronic Q fever.

Rab conversion as a mechanism of progression from early to late endosomes.

The uptake of apoptotic cells drives Coxiella burnetii replication and macrophage polarization: a model for Q fever endocarditis.

Ameobal pathogen mimivirus infects macrophages through phagocytosis.

Tropheryma whipplei glycosylation in the pathophysiologic profile of Whipple's disease.

Intracellular life of Coxiella burnetii in macrophages.

Type I interferon induction is detrimental during infection with the Whipple's disease bacterium, Tropheryma whipplei.

A dilemma for viruses and giant viruses: which endocytic pathway to use to enter cells?

Hijacked phagosomes and leukocyte activation: an intimate relationship.

IL-16 promotes T. whipplei replication by inhibiting phagosome conversion and modulating macrophage activation.

Coxiella burnetii, the agent of Q fever, replicates within trophoblasts and induces a unique transcriptional response.

Orientia tsutsugamushi stimulates an original gene expression program in monocytes: relationship with gene expression in patients with scrub typhus.

The intensity of IUGR-induced transcriptome deregulations is inversely correlated with the onset of organ function in a rat model.

Ligand of Numb proteins LNX1p80 and LNX2 interact with the human glycoprotein CD8α and promote its ubiquitylation and endocytosis.

Antibiotic susceptibility and intracellular localization of Diplorickettsia massiliensis.

The ligands of Numb proteins X1 and X2 are specific markers for chronic Q fever.

Effects of Coxiella burnetii on MAPKinases phosphorylation.

Foxp3(+)CD4(+)CD25(+) regulatory T cells are increased in patients with Coxiella burnetii endocarditis.

Defective monocyte dynamics in Q fever granuloma deficiency.

The Coxiella burnetii parasitophorous vacuole.

Whole-cell MALDI-TOF MS: a new tool to assess the multifaceted activation of macrophages.

Orientia tsutsugamushi, the causative agent of scrub typhus, induces an inflammatory program in human macrophages.

Impaired stimulation of p38α-MAPK/Vps41-HOPS by LPS from pathogenic Coxiella burnetii prevents trafficking to microbicidal phagolysosomes.

Tobacco mosaic virus in the lungs of mice following intra-tracheal inoculation.

PC3 (BTG2/TIS21) possible role in chromosome instability syndromes.

[Lipopolysaccharide of Coxiella burnetii controls bacterial phagolysosome degradation].

Monocyte responses in the context of Q fever: from a static polarized model to a kinetic model of activation.

Placental macrophages are impaired in chorioamnionitis, an infectious pathology of the placenta.