George Dimopoulos

Genome expression analysis of Anopheles gambiae: responses to injury, bacterial challenge, and malaria infection.

Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster.

Immunity-related genes and gene families in Anopheles gambiae.

Insect immunity and its implication in mosquito-malaria interactions.

Optimal adrenergic support in septic shock due to peritonitis.

Low-dose vasopressin in the treatment of septic shock in sheep.

SOAP, a novel malaria ookinete protein involved in mosquito midgut invasion and oocyst development.

Gut mucosal damage during endotoxic shock is due to mechanisms other than gut ischemia.

Are infections due to resistant pathogens associated with a worse outcome in critically ill patients?

The role of reactive oxygen species on Plasmodium melanotic encapsulation in Anopheles gambiae.

Analysis of the Plasmodium and Anopheles transcriptomes during oocyst differentiation.

Analysis of the Plasmodium and Anopheles transcriptional repertoire during ookinete development and midgut invasion.

The effect of hyperosmotic pressure on antibody production and gene expression in the GS-NS0 cell line.

[Roles of hydroxyethyl starch solution in resuscitation for shock induced by ischemia/reperfusion injury of the intestine].

Immediate post-operative effects of tracheotomy on respiratory function during mechanical ventilation.

Post mortem examination in the intensive care unit: still useful?

[Comparison of dobutamine under different fluids resuscitation for shock induced by ischemia/reperfusion].

Transcript profiles of Blumeria graminis development during infection reveal a cluster of genes that are potential virulence determinants.

Global gene expression analysis of Anopheles gambiae responses to microbial challenge.

Transcriptome analysis of Anopheles stephensi-Plasmodium berghei interactions.

Anopheles infection responses; laboratory models versus field malaria transmission systems.

Treatment of vascular smooth muscle cells with estradiol and beta-adrenergic agonists has an additive effect on cAMP levels, but no additive effect on inhibition of collagen synthesis.

Recombinant human erythropoietin therapy in critically ill patients: a dose-response study [ISRCTN48523317].

Bayesian coclustering of Anopheles gene expression time series: study of immune defense response to multiple experimental challenges.

Blood warming during hemofiltration can improve hemodynamics and outcome in ovine septic shock.

AgDscam, a hypervariable immunoglobulin domain-containing receptor of the Anopheles gambiae innate immune system.

Anopheles gambiae immune responses to human and rodent Plasmodium parasite species.

[Hospital-acquired pneumonia caused by methicillin-resistant Staphylococcus aureus].

Regulation of sexual development of Plasmodium by translational repression.

Anopheles gambiae immune responses to Sephadex beads: involvement of anti-Plasmodium factors in regulating melanization.

Ca2+-dependent rapid Ca2+ sensitization of contraction in arterial smooth muscle.

Spatial and sex-specific dissection of the Anopheles gambiae midgut transcriptome.

Genome sequence of Aedes aegypti, a major arbovirus vector.

Comparison of first-line with second-line antibiotics for acute exacerbations of chronic bronchitis: a metaanalysis of randomized controlled trials.

Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes.

Antibiotics selection for bacteremic pneumonia.

Immunoglobulin superfamily members play an important role in the mosquito immune system.

Continuous exposure to Plasmodium results in decreased susceptibility and transcriptomic divergence of the Anopheles gambiae immune system.

Ventilator-associated pneumonia: impact of organisms on clinical resolution and medical resources utilization.

Candida albicans versus non-albicans intensive care unit-acquired bloodstream infections: differences in risk factors and outcome.

Fluoroquinolones compared with beta-lactam antibiotics for the treatment of acute bacterial sinusitis: a meta-analysis of randomized controlled trials.

Short- versus long-duration antimicrobial treatment for exacerbations of chronic bronchitis: a meta-analysis.

Gene discovery in an invasive tephritid model pest species, the Mediterranean fruit fly, Ceratitis capitata.

Chloroquine mediated modulation of Anopheles gambiae gene expression.

The Aedes aegypti toll pathway controls dengue virus infection.

Comparison of antibiotics with placebo for treatment of acute sinusitis: a meta-analysis of randomised controlled trials.

Short- versus long-course antibacterial therapy for community-acquired pneumonia : a meta-analysis.

Is Candida really a threat in the ICU?

Inhibition of phosphodiesterase has an additive effect on estrogen's ability to inhibit collagen synthesis in vascular smooth muscle cells.

Early switch to oral treatment in patients with moderate to severe community-acquired pneumonia: a meta-analysis.

Centers for Disease Control and Prevention guidelines for preventing central venous catheter-related infection: results of a knowledge test among 3405 European intensive care nurses.

Molecular analysis of photic inhibition of blood-feeding in Anopheles gambiae.

Therapeutic options for Burkholderia cepacia infections beyond co-trimoxazole: a systematic review of the clinical evidence.

A 10-year survey of antifungal susceptibility of candidemia isolates from intensive care unit patients in Greece.

Clinical significance of the pharmacokinetic and pharmacodynamic characteristics of tigecycline.

Penicillins vs trimethoprim-based regimens for acute bacterial exacerbations of chronic bronchitis: meta-analysis of randomized controlled trials.

Temporal trends, risk factors and outcomes in albicans and non-albicans candidaemia: an international epidemiological study in four multidisciplinary intensive care units.

Effects of dobutamine on gut mucosal nitric oxide production during endotoxic shock in rabbits.

Anopheles fibrinogen-related proteins provide expanded pattern recognition capacity against bacteria and malaria parasites.

Challenges and approaches for mosquito targeted malaria control.

Caspar controls resistance to Plasmodium falciparum in diverse anopheline species.

Impact of patient position on the incidence of ventilator-associated pneumonia: a meta-analysis of randomized controlled trials.

Meta-analyses on the prevention and treatment of respiratory tract infections.

Discovery of insect and human dengue virus host factors.

Implication of the mosquito midgut microbiota in the defense against malaria parasites.

Genome-wide transcriptomic profiling of Anopheles gambiae hemocytes reveals pathogen-specific signatures upon bacterial challenge and Plasmodium berghei infection.

Approach to the febrile patient in the ICU.

An evolutionary conserved function of the JAK-STAT pathway in anti-dengue defense.

Molecular discrimination of mosquito vectors and their pathogens.

Mosquito infection responses to developing filarial worms.

Attributable mortality of Stenotrophomonas maltophilia infections: a systematic review of the literature.

Mosquito immune defenses against Plasmodium infection.

The Toll immune signaling pathway control conserved anti-dengue defenses across diverse Ae. aegypti strains and against multiple dengue virus serotypes.

Universal features of post-transcriptional gene regulation are critical for Plasmodium zygote development.

Dengue virus inhibits immune responses in Aedes aegypti cells.

Genome-wide analysis of transcriptomic divergence between laboratory colony and field Anopheles gambiae mosquitoes of the M and S molecular forms.

H1N1v influenza vaccine in Greek medical students.

Post-operative Aspergillus mediastinitis in a man who was immunocompetent: a case report.

Early changes of procalcitonin may advise about prognosis and appropriateness of antimicrobial therapy in sepsis.

Sequencing of Culex quinquefasciatus establishes a platform for mosquito comparative genomics.

Pathogenomics of Culex quinquefasciatus and meta-analysis of infection responses to diverse pathogens.

Transcriptomic and functional analysis of the Anopheles gambiae salivary gland in relation to blood feeding.

Risk assessment and prognostic factors for mould-related diseases in immunocompromised patients.

Natural microbe-mediated refractoriness to Plasmodium infection in Anopheles gambiae.

Soluble urokinase plasminogen activator receptor (suPAR) for assessment of disease severity in ventilator-associated pneumonia and sepsis.

Low- and high-tech approaches to control Plasmodium parasite transmission by anopheles mosquitoes.

Chemotherapy-induced neutropenia in lung cancer patients: the role of antibiotic prophylaxis.

Native microbiota shape insect vector competence for human pathogens.

Transcriptome analysis of Aedes aegypti transgenic mosquitoes with altered immunity.

The entomopathogenic fungus Beauveria bassiana activate toll and JAK-STAT pathway-controlled effector genes and anti-dengue activity in Aedes aegypti.

Engineered anopheles immunity to Plasmodium infection.

Transcriptome Profiling of Sexual Maturation and Mating in the Mediterranean Fruit Fly, Ceratitis capitata.

Reciprocal tripartite interactions between the Aedes aegypti midgut microbiota, innate immune system and dengue virus influences vector competence.

Dengue virus infection of the Aedes aegypti salivary gland and chemosensory apparatus induces genes that modulate infection and blood-feeding behavior.

A clinical algorithm to diagnose invasive pulmonary aspergillosis in critically ill patients.

An ESICM systematic review and meta-analysis of procalcitonin-guided antibiotic therapy algorithms in adult critically ill patients.

Anopheles Imd pathway factors and effectors in infection intensity-dependent anti-Plasmodium action.

DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic.

Risk assessment in sepsis: a new prognostication rule by APACHE II score and serum soluble urokinase plasminogen activator receptor.

Efficacy and safety of anidulafungin in elderly, critically ill patients with invasive Candida infections: a post hoc analysis.

Transcriptional mediators Kto and Skd are involved in the regulation of the IMD pathway and anti-Plasmodium defense in Anopheles gambiae.

Anopheles NF-κB-regulated splicing factors direct pathogen-specific repertoires of the hypervariable pattern recognition receptor AgDscam.

Caudal is a negative regulator of the Anopheles IMD pathway that controls resistance to Plasmodium falciparum infection.

Invasive aspergillosis in the intensive care unit.

Potentially resistant microorganisms in intubated patients with hospital-acquired pneumonia: the interaction of ecology, shock and risk factors.

Echinocandins in invasive candidiasis.

Wolbachia invades Anopheles stephensi populations and induces refractoriness to Plasmodium infection.

Controversies in the management of the critically ill: the role of probiotics.

Short- vs long-duration antibiotic regimens for ventilator-associated pneumonia: a systematic review and meta-analysis.

Transcriptomic profiling of diverse Aedes aegypti strains reveals increased basal-level immune activation in dengue virus-refractory populations and identifies novel virus-vector molecular interactions.

What is the relevance of fosfomycin pharmacokinetics in the treatment of serious infections in critically ill patients? A systematic review.

L-asparaginase fatal toxic encephalopathy during consolidation treatment in an adult with acute lymphoblastic leukemia.

The Anopheles innate immune system in the defense against malaria infection.

How to select an antifungal agent in critically ill patients.

Bacteria- and IMD pathway-independent immune defenses against Plasmodium falciparum in Anopheles gambiae.

Treatment of invasive candidiasis in the elderly: a review.

Aedes aegypti ML and Niemann-Pick type C family members are agonists of dengue virus infection.

Prevalence, risk factors, and mortality for ventilator-associated pneumonia in middle-aged, old, and very old critically ill patients*.

Outcomes of critically ill intensive care unit patients treated with fosfomycin for infections due to pandrug-resistant and extensively drug-resistant carbapenemase-producing Gram-negative bacteria.

Cerebral aspergillosis in adult critically ill patients: a descriptive report of 10 patients from the AspICU cohort.

Diagnosis and management of temperature abnormality in ICUs: a EUROBACT investigators' survey.

Exploring Anopheles gut bacteria for Plasmodium blocking activity.

DALI: defining antibiotic levels in intensive care unit patients: are current β-lactam antibiotic doses sufficient for critically ill patients?

Invasive fungal infections in the ICU: how to approach, how to treat.

Critically ill elderly adults with infection: analysis of the extended prevalence of infection in intensive care study.

What is new in infection prevention in critical care in 2014?

Reply to Rhodes et al.

Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study.

What is new in the use of aminoglycosides in critically ill patients?

Characterization of the Rel2-regulated transcriptome and proteome of Anopheles stephensi identifies new anti-Plasmodium factors.

Yeast central nervous system infection in a critically ill patient: a case report.

Inhaled corticosteroids and Aspergillus fumigatus isolation in cystic fibrosis.

Suppressing dengue-2 infection by chemical inhibition of Aedes aegypti host factors.

Gametocytocidal screen identifies novel chemical classes with Plasmodium falciparum transmission blocking activity.

Chromobacterium Csp_P reduces malaria and dengue infection in vector mosquitoes and has entomopathogenic and in vitro anti-pathogen activities.

Current and future treatment options for infections caused by multidrug-resistant Gram-negative pathogens.

The insect microbiome modulates vector competence for arboviruses.

Mosquito immunity against arboviruses.

MicroRNA-regulation of Anopheles gambiae immunity to Plasmodium falciparum infection and midgut microbiota.

The mosquito microbiota influences vector competence for human pathogens.

Cytoplasmic actin is an extracellular insect immune factor which is secreted upon immune challenge and mediates phagocytosis and direct killing of bacteria, and is a Plasmodium Antagonist.

Anopheles Midgut FREP1 Mediates Plasmodium Invasion.

A mosquito mediator of parasite-induced immune priming.

Heme Signaling Impacts Global Gene Expression, Immunity and Dengue Virus Infectivity in Aedes aegypti.

Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection.

Mosquito gut antiparasitic and antiviral immunity.

Emerging role of lipid droplets in Aedes aegypti immune response against bacteria and Dengue virus.

Functional genomic analyses of Enterobacter, Anopheles and Plasmodium reciprocal interactions that impact vector competence.

The Anopheles FBN9 immune factor mediates Plasmodium species-specific defense through transgenic fat body expression.

The Golgi associated ERI3 is a Flavivirus host factor.

Comprehensive DNA methylation analysis of the Aedes aegypti genome.

Engineered Aedes aegypti JAK/STAT Pathway-Mediated Immunity to Dengue Virus.

Molecular analysis of Culex quinquefasciatus larvae responses to Lysinibacillus sphaericus Bin toxin.

Association of microRNAs with Argonaute proteins in the malaria mosquito Anopheles gambiae after blood ingestion.

Amino acid metabolic signaling influences Aedes aegypti midgut microbiome variability.

Changes in the microbiota cause genetically modified to spread in a population.

Immune Regulation of Is Species Specific and Infection Intensity Dependent.

Molecular Responses to Zika Virus: Modulation of Infection by the Toll and Jak/Stat Immune Pathways and Virus Host Factors.

Immune response-related genes associated to blocking midgut dengue virus infection in Aedes aegypti strains that differ in susceptibility.

CRISPR/Cas9 -mediated gene knockout of Anopheles gambiae FREP1 suppresses malaria parasite infection.

The mosquito adulticidal Chromobacterium sp. Panama causes transgenerational impacts on fitness parameters and elicits xenobiotic gene responses.

Immunization with AgTRIO, a Protein in Anopheles Saliva, Contributes to Protection against Plasmodium Infection in Mice.

Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin.

Aminopeptidase secreted by Chromobacterium sp. Panama inhibits dengue virus infection by degrading the E protein.

Regulation of midgut cell proliferation impacts Aedes aegypti susceptibility to dengue virus.

Diverse Host and Restriction Factors Regulate Mosquito-Pathogen Interactions.

Hydrogen cyanide produced by the soil bacterium Chromobacterium sp. Panama contributes to mortality in Anopheles gambiae mosquito larvae.

A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission.

Curious entanglements: interactions between mosquitoes, their microbiota, and arboviruses.

Lacking Inefficiently Transmits to Mice.

Combining Sterile and Incompatible Insect Techniques for Aedes albopictus Suppression.

Identification of anti-flaviviral drugs with mosquitocidal and anti-Zika virus activity in Aedes aegypti.

Bacterial natural products in the fight against mosquito-transmitted tropical diseases.

Disruption of mosGILT in Anopheles gambiae impairs ovarian development and Plasmodium infection.

A Nonlive Preparation of sp. Panama (Csp_P) Is a Highly Effective Larval Mosquito Biopesticide.

Broad spectrum immunomodulatory effects of Anopheles gambiae microRNAs and their use for transgenic suppression of Plasmodium.

Dynamic miRNA-mRNA interactions coordinate gene expression in adult Anopheles gambiae.

Versatile transgenic multistage effector-gene combinations for suppression in .

Inhibition of in Adult Mosquitoes Causes Male-Specific Mortality and Diverse Transcriptome Changes.