Claire M. Dubois

Furin gene (fur) regulation in differentiating human megakaryoblastic Dami cells: involvement of the proximal GATA recognition motif in the P1 promoter and impact on the maturation of furin substrates.

Novel insights into cadherin processing by subtilisin-like convertases.

TACE/ADAM-17 maturation and activation of sheddase activity require proprotein convertase activity.

Alternative pathway for the role of furin in tumor cell invasion process. Enhanced MMP-2 levels through bioactive TGFbeta.

Hypoxia-enhanced expression of the proprotein convertase furin is mediated by hypoxia-inducible factor-1: impact on the bioactivation of proproteins.

The CDX2 transcription factor regulates furin expression during intestinal epithelial cell differentiation.

Lipopolysaccharide mediated regulation of neuroendocrine associated proprotein convertases and neuropeptide precursor processing in the rat spleen.

The serpin proteinase inhibitor 8: an endogenous furin inhibitor released from human platelets.

Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression.

Differential involvement of NF-kappaB and MAP kinase pathways in the generation of inflammatory cytokines by human neutrophils.

Sox9-dependent transcriptional regulation of the proprotein convertase furin.

Hypoxia-inducible factor mediates hypoxic and tumor necrosis factor alpha-induced increases in tumor necrosis factor-alpha converting enzyme/ADAM17 expression by synovial cells.

Leukotriene D4 up-regulates furin expression through CysLT1 receptor signaling.

Inflammatory cytokine production by human neutrophils involves C/EBP transcription factors.

Autotaxin promotes cancer invasion via the lysophosphatidic acid receptor 4: participation of the cyclic AMP/EPAC/Rac1 signaling pathway in invadopodia formation.

Formation of invadopodia-like structures by synovial cells promotes cartilage breakdown in collagen-induced arthritis: involvement of the protein tyrosine kinase Src.

Hypoxia enhances cancer cell invasion through relocalization of the proprotein convertase furin from the trans-Golgi network to the cell surface.

Hypoxia-induced invadopodia formation involves activation of NHE-1 by the p90 ribosomal S6 kinase (p90RSK).

Transglutaminase 2 cross-linking activity is linked to invadopodia formation and cartilage breakdown in arthritis.

HDAC6 deacetylase activity is required for hypoxia-induced invadopodia formation and cell invasion.

The p38-MSK1 signaling cascade influences cytokine production through CREB and C/EBP factors in human neutrophils.