Martin Friedlander

A fragment of human TrpRS as a potent antagonist of ocular angiogenesis.

A human aminoacyl-tRNA synthetase as a regulator of angiogenesis.

Loss of p53 compensates for alpha v-integrin function in retinal neovascularization.

Insulin-like growth factor 2 and potential regulators of hemangioma growth and involution identified by large-scale expression analysis.

The amino terminus of opsin translocates "posttranslationally" as efficiently as cotranslationally.

Bone marrow-derived stem cells target retinal astrocytes and can promote or inhibit retinal angiogenesis.

Retinal vascular development is mediated by endothelial filopodia, a preexisting astrocytic template and specific R-cadherin adhesion.

Co-translational targeting and translocation of the amino terminus of opsin across the endoplasmic membrane requires GTP but not ATP.

In vivo transduction of photoreceptors or ciliary body by intravitreal injection of pseudotyped adenoviral vectors.

Endothelial proliferation in diabetic retinal microaneurysms.

Mouse model of subretinal neovascularization with choroidal anastomosis.

Adult bone marrow-derived stem cells use R-cadherin to target sites of neovascularization in the developing retina.

Global gene expression analysis of the developing postnatal mouse retina.

Regulation of angiogenesis by tissue factor cytoplasmic domain signaling.

Functional adult myocardium in the absence of Na+-Ca2+ exchange: cardiac-specific knockout of NCX1.

Rescue of retinal degeneration by intravitreally injected adult bone marrow-derived lineage-negative hematopoietic stem cells.

Identifying potential regulators of infantile hemangioma progression through large-scale expression analysis: a possible role for the immune system and indoleamine 2,3 dioxygenase (IDO) during involution.

Retinal vascular regeneration.

Three-dimensional in vivo imaging of the mouse intraocular vasculature during development and disease.

Recent progress in our understanding of the pathogenesis of infantile hemangiomas.

Myeloid cells in infantile hemangioma.

A homing mechanism for bone marrow-derived progenitor cell recruitment to the neovasculature.

Mechanisms of endothelial cell guidance and vascular patterning in the developing mouse retina.

T2-TrpRS inhibits preretinal neovascularization and enhances physiological vascular regrowth in OIR as assessed by a new method of quantification.

Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California).

Myeloid progenitors differentiate into microglia and promote vascular repair in a model of ischemic retinopathy.

Combination angiostatic therapy completely inhibits ocular and tumor angiogenesis.

Ocular neovascularization: basic mechanisms and therapeutic advances.

Fibrosis and diseases of the eye.

Role of protease activated receptor 1 and 2 signaling in hypoxia-induced angiogenesis.

Progenitor cells and retinal angiogenesis.

Hypertrophy and heart failure in mice overexpressing the cardiac sodium-calcium exchanger.

Pathogenesis of infantile haemangioma: new molecular and cellular insights.

Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits.

Introducing Lois E. H. Smith, the 2008 recipient of the Friedenwald Award.

Chapter 6. Ocular models of angiogenesis.

Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress.

Maintaining retinal astrocytes normalizes revascularization and prevents vascular pathology associated with oxygen-induced retinopathy.

Combination angiostatic therapies: targeting multiple angiogenic pathways.

Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina.

Stemming vision loss with stem cells.

Analysis of candidate genes for macular telangiectasia type 2.

Astrocyte pVHL and HIF-α isoforms are required for embryonic-to-adult vascular transition in the eye.

Differential macrophage polarization promotes tissue remodeling and repair in a model of ischemic retinopathy.

Generation of retinal pigment epithelial cells from small molecules and OCT4 reprogrammed human induced pluripotent stem cells.

Advances in treatment and management: immunologic and cell-based regenerative therapies.

Using flow cytometry to compare the dynamics of photoreceptor outer segment phagocytosis in iPS-derived RPE cells.

Targeted deletion of Vegfa in adult mice induces vision loss.

Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting.

Hypoxia-inducible factor (HIF)/vascular endothelial growth factor (VEGF) signaling in the retina.

Utilizing stem cell-derived RPE cells as a therapeutic intervention for age-related macular degeneration.

Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye.

Comprehensive bioimaging with fluorinated nanoparticles using breathable liquids.

Neurovascular crosstalk between interneurons and capillaries is required for vision.

Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells.

Global metabolomics reveals metabolic dysregulation in ischemic retinopathy.

A Challenging Form of Non-autoimmune Insulin-Dependent Diabetes in a Wolfram Syndrome Patient with a Novel Sequence Variant.

iPSC-Derived Retinal Pigment Epithelium Allografts Do Not Elicit Detrimental Effects in Rats: A Follow-Up Study.

Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1.

Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration.

Corrigendum: Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1.

CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy.

Quantitative metabolomics of photoreceptor degeneration and the effects of stem cell-derived retinal pigment epithelium transplantation.

VEGF regulates local inhibitory complement proteins in the eye and kidney.

CD44 expression in endothelial colony-forming cells regulates neurovascular trophic effect.

Genome-wide analyses identify common variants associated with macular telangiectasia type 2.

Antibody-Mediated Inhibition of Tspan12 Ameliorates Vasoproliferative Retinopathy Through Suppression of β-Catenin Signaling.

Special Commentary: Early Clinical Development of Cell Replacement Therapy: Considerations for the National Eye Institute Audacious Goals Initiative.

Angiogenesis and Eye Disease.

Global Connections to Study Idiopathic Macular Telangiectasia Type 2.

Fully automated, deep learning segmentation of oxygen-induced retinopathy images.

Effect of Ciliary Neurotrophic Factor on Retinal Neurodegeneration in Patients with Macular Telangiectasia Type 2: A Randomized Clinical Trial.

Metabolomics in the study of retinal health and disease.

miR-30a-5p inhibition promotes interaction of Fas endothelial cells and FasL microglia to decrease pathological neovascularization and promote physiological angiogenesis.

The long dystrophin gene product Dp427 modulates retinal function and vascular morphology in response to age and retinal ischemia.

Anti-VEGF therapy: higher potency and long-lasting antagonism are not necessarily better.

Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy.

Beyond Performance Metrics: Automatic Deep Learning Retinal OCT Analysis Reproduces Clinical Trial Outcome.

Retinal microglia are critical for subretinal neovascular formation.

Optical coherence tomography-angiography for monitoring neovascularisations in macular telangiectasia type 2.

Systemic lipid dysregulation is a risk factor for macular neurodegenerative disease.

CNTF Prevents Development of Outer Retinal Neovascularization Through Upregulation of CxCl10.

An allosteric peptide inhibitor of HIF-1α regulates hypoxia-induced retinal neovascularization.

Deep learning-based classification and segmentation of retinal cavitations on optical coherence tomography images of macular telangiectasia type 2.

WITHDRAWN: Hyper-reflectivity on optical coherence tomography in macular telangiectasia type 2.

Hyper-reflectivity on optical coherence tomography in macular telangiectasia type 2.

Identification of genetic factors influencing metabolic dysregulation and retinal support for MacTel, a retinal disorder.