Department of Medicine,
Pulmonary Hypertension Research Group (CRIUCPQ),
Department of Medicine, Pulmonary Hypertension Research Group (CRIUCPQ)
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Reversal of chronic hypoxia-induced alterations in pulmonary artery smooth muscle electromechanical coupling upon air breathing.
Cardiovascular research Mar, 2002 | Pubmed ID: 11922912
Upregulation of L-type Ca2+ channels in mesenteric and skeletal arteries of SHR.
Hypertension Aug, 2002 | Pubmed ID: 12154116
Dehydroepiandrosterone (DHEA) prevents and reverses chronic hypoxic pulmonary hypertension.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2003 | Pubmed ID: 12878719
Role of Ca(2+)-sensitive K(+) channels in the remission phase of pulmonary hypertension in chronic obstructive pulmonary diseases.
Cardiovascular research Nov, 2003 | Pubmed ID: 14613862
Sildenafil alters calcium signaling and vascular tone in pulmonary arteries from chronically hypoxic rats.
American journal of physiology. Lung cellular and molecular physiology Sep, 2004 | Pubmed ID: 15155272
Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.
Circulation research Aug, 2004 | Pubmed ID: 15217912
Chronic hypoxia induces nonreversible right ventricle dysfunction and dysplasia in rats.
American journal of physiology. Heart and circulatory physiology Sep, 2004 | Pubmed ID: 15317673
Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis.
Circulation research Oct, 2004 | Pubmed ID: 15375007
Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.
The Journal of clinical investigation Jun, 2005 | Pubmed ID: 15931388
Sildenafil improves alveolar growth and pulmonary hypertension in hyperoxia-induced lung injury.
American journal of respiratory and critical care medicine Sep, 2005 | Pubmed ID: 15947285
Discovery of benzylidenebenzofuran-3(2H)-one (aurones) as inhibitors of tyrosinase derived from human melanocytes.
Journal of medicinal chemistry Jan, 2006 | Pubmed ID: 16392817
Analogues of N-hydroxycinnamoylphenalkylamides as inhibitors of human melanocyte-tyrosinase.
Bioorganic & medicinal chemistry letters Apr, 2006 | Pubmed ID: 16442796
A central role for oxygen-sensitive K+ channels and mitochondria in the specialized oxygen-sensing system.
Novartis Foundation symposium , 2006 | Pubmed ID: 16686435
An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.
Circulation Jun, 2006 | Pubmed ID: 16735674
Absence of malonyl coenzyme A decarboxylase in mice increases cardiac glucose oxidation and protects the heart from ischemic injury.
Circulation Oct, 2006 | Pubmed ID: 17030679
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.
Cancer cell Jan, 2007 | Pubmed ID: 17222789
Potassium channel diversity in the pulmonary arteries and pulmonary veins: implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension.
Pharmacology & therapeutics Jul, 2007 | Pubmed ID: 17583356
The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2007 | Pubmed ID: 17596340
Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study.
American journal of physiology. Lung cellular and molecular physiology Oct, 2007 | Pubmed ID: 17675370
CD36 expression contributes to age-induced cardiomyopathy in mice.
Circulation Nov, 2007 | Pubmed ID: 17967771
Air pollutant emissions from rice straw open field burning in India, Thailand and the Philippines.
Environmental pollution (Barking, Essex : 1987) May, 2009 | Pubmed ID: 19201513
Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats.
American journal of respiratory and critical care medicine Dec, 2009 | Pubmed ID: 19713449
Dehydroepiandrosterone reverses systemic vascular remodeling through the inhibition of the Akt/GSK3-{beta}/NFAT axis.
Circulation Sep, 2009 | Pubmed ID: 19752325
Dehydroepiandrosterone: A new treatment for vascular remodeling diseases including pulmonary arterial hypertension.
Pharmacology & therapeutics May, 2010 | Pubmed ID: 20206649
HIF-1 inhibition decreases systemic vascular remodelling diseases by promoting apoptosis through a hexokinase 2-dependent mechanism.
Cardiovascular research Oct, 2010 | Pubmed ID: 20498255
Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension.
Science translational medicine Aug, 2010 | Pubmed ID: 20702857
Tumor necrosis factor inhibitors as novel therapeutic tools for vascular remodeling diseases.
American journal of physiology. Heart and circulatory physiology Oct, 2010 | Pubmed ID: 20709868
Role for miR-204 in human pulmonary arterial hypertension.
The Journal of experimental medicine Mar, 2011 | Pubmed ID: 21321078
Signal transducers and activators of transcription-3/pim1 axis plays a critical role in the pathogenesis of human pulmonary arterial hypertension.
Circulation Mar, 2011 | Pubmed ID: 21382889
RAGE-dependent activation of the oncoprotein Pim1 plays a critical role in systemic vascular remodeling processes.
Arteriosclerosis, thrombosis, and vascular biology Sep, 2011 | Pubmed ID: 21680901
The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension.
Science translational medicine Jun, 2011 | Pubmed ID: 21697531
From oncoproteins/tumor suppressors to microRNAs, the newest therapeutic targets for pulmonary arterial hypertension.
Journal of molecular medicine (Berlin, Germany) Nov, 2011 | Pubmed ID: 21761156
Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension.
Journal of molecular medicine (Berlin, Germany) Aug, 2011 | Pubmed ID: 21809123
Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension.
American journal of physiology. Heart and circulatory physiology Nov, 2011 | Pubmed ID: 21890685
Krüppel-like factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension.
Respiratory research , 2011 | Pubmed ID: 21951574
Today's and tomorrow's imaging and circulating biomarkers for pulmonary arterial hypertension.
Cellular and molecular life sciences : CMLS Sep, 2012 | Pubmed ID: 22446747
Plumbagin reverses proliferation and resistance to apoptosis in experimental PAH.
The European respiratory journal Sep, 2012 | Pubmed ID: 22496325
Framework for life cycle sustainability assessment of municipal solid waste management systems with an application to a case study in Thailand.
Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA Jul, 2012 | Pubmed ID: 22605020
Repeatability and responsiveness of exercise tests in pulmonary arterial hypertension.
The European respiratory journal Aug, 2013 | Pubmed ID: 23100508
Ozone and its potential control strategy for Chon Buri city, Thailand.
Journal of the Air & Waste Management Association (1995) Dec, 2012 | Pubmed ID: 23362760
The emergence of new therapeutic targets in pulmonary arterial hypertension: from now to the near future.
Expert review of respiratory medicine Feb, 2013 | Pubmed ID: 23362814
Critical role for the advanced glycation end-products receptor in pulmonary arterial hypertension etiology.
Journal of the American Heart Association Feb, 2013 | Pubmed ID: 23525442
Uncoupling protein 2 deficiency mimics the effects of hypoxia and endoplasmic reticulum stress on mitochondria and triggers pseudohypoxic pulmonary vascular remodeling and pulmonary hypertension.
Circulation research Jul, 2013 | Pubmed ID: 23652801
Pim-1: A new biomarker in pulmonary arterial hypertension.
Pulmonary circulation Jan, 2013 | Pubmed ID: 23662177
Therapeutic Potential of microRNA Modulation in Pulmonary Arterial Hypertension.
Current vascular pharmacology May, 2013 | Pubmed ID: 23713859
Targeting cell motility in pulmonary arterial hypertension.
The European respiratory journal Feb, 2014 | Pubmed ID: 23845719
Signal transduction in the development of pulmonary arterial hypertension.
Pulmonary circulation Apr, 2013 | Pubmed ID: 24015329
STAT3 signaling in pulmonary arterial hypertension.
JAK-STAT Oct, 2012 | Pubmed ID: 24058777
Anti-inflammatory and immunosuppressive agents in PAH.
Handbook of experimental pharmacology , 2013 | Pubmed ID: 24092351
Role for DNA damage signaling in pulmonary arterial hypertension.
Circulation Feb, 2014 | Pubmed ID: 24270264
Effect of pulmonary arterial hypertension-specific therapies on health-related quality of life: a systematic review.
Chest Sep, 2014 | Pubmed ID: 24626791
miRNAs in PAH: biomarker, therapeutic target or both?
Drug discovery today Aug, 2014 | Pubmed ID: 24881781
Apolipoprotein A-I mimetic peptide 4F rescues pulmonary hypertension by inducing microRNA-193-3p.
Circulation Aug, 2014 | Pubmed ID: 24963038
Impaired angiogenesis and peripheral muscle microcirculation loss contribute to exercise intolerance in pulmonary arterial hypertension.
American journal of respiratory and critical care medicine Aug, 2014 | Pubmed ID: 24977625
Vascular remodeling process in pulmonary arterial hypertension, with focus on miR-204 and miR-126 (2013 Grover Conference series).
Pulmonary circulation Jun, 2014 | Pubmed ID: 25006436
Alternatives to the six-minute walk test in pulmonary arterial hypertension.
PloS one , 2014 | Pubmed ID: 25111294
Sirtuin 3 deficiency is associated with inhibited mitochondrial function and pulmonary arterial hypertension in rodents and humans.
Cell metabolism Nov, 2014 | Pubmed ID: 25284742
A miR-208-Mef2 axis drives the decompensation of right ventricular function in pulmonary hypertension.
Circulation research Jan, 2015 | Pubmed ID: 25287062
Skeletal muscle proteomic signature and metabolic impairment in pulmonary hypertension.
Journal of molecular medicine (Berlin, Germany) May, 2015 | Pubmed ID: 25548805
Adaptation and Remodelling of the Pulmonary Circulation in Pulmonary Hypertension.
The Canadian journal of cardiology Apr, 2015 | Pubmed ID: 25630876
NOGGIN: a new therapeutic target for PH? Focus on "Noggin Inhibits Hypoxia-Induced Proliferation by Targeting Store-operated Calcium Entry and TRPC Channels".
American journal of physiology. Cell physiology Apr, 2015 | Pubmed ID: 25832472
1Department of Medicine, Pulmonary Hypertension Research Group (CRIUCPQ), Laval University,
2, Institut National de la Recherche Agronomique,
3Université Diderot Paris, Sorbonne Paris Cité,
4Hôpital Lariboisière, Physiologie clinique Explorations Fonctionnelles,
5, INSERM U 965,
6Service de Cardiologie, Centre Hospitalier Universitaire Tours
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