Department of Cardiology and Angiology I
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Transgenic overexpression of the oncofetal RNA binding protein KOC leads to remodeling of the exocrine pancreas.
Gastroenterology Jun, 2003 | Pubmed ID: 12806623
Contrast ultrasound perfusion imaging of lower extremities in peripheral arterial disease: a novel diagnostic method.
European heart journal Feb, 2006 | Pubmed ID: 16308326
Simplified contrast ultrasound accurately reveals muscle perfusion deficits and reflects collateralization in PAD.
Atherosclerosis Feb, 2009 | Pubmed ID: 18606414
Platelet granule secretion continuously prevents intratumor hemorrhage.
Cancer research Aug, 2008 | Pubmed ID: 18701510
Petechial bleeding after sunburn in a patient with mild thrombocytopenia.
American journal of hematology Aug, 2009 | Pubmed ID: 19021121
p38 mitogen-activated protein kinase activation during platelet storage: consequences for platelet recovery and hemostatic function in vivo.
Blood Mar, 2010 | Pubmed ID: 19965619
Integrin-independent role of CalDAG-GEFI in neutrophil chemotaxis.
Journal of leukocyte biology Aug, 2010 | Pubmed ID: 20413728
A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function.
The Journal of experimental medicine Aug, 2010 | Pubmed ID: 20713593
Extracellular DNA traps promote thrombosis.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2010 | Pubmed ID: 20798043
Clopidogrel in acute coronary syndrome: implications of recent study findings.
Expert review of cardiovascular therapy Sep, 2010 | Pubmed ID: 20828343
Success of arterial revascularization determined by contrast ultrasound muscle perfusion imaging.
Journal of vascular surgery Dec, 2010 | Pubmed ID: 20843628
Molecular magnetic resonance imaging allows the detection of activated platelets in a new mouse model of coronary artery thrombosis.
Investigative radiology Oct, 2011 | Pubmed ID: 21577120
BMP activity controlled by BMPER regulates the proinflammatory phenotype of endothelium.
Blood Nov, 2011 | Pubmed ID: 21900199
Binding of CD40L to Mac-1's I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis--but does not affect immunity and thrombosis in mice.
Circulation research Nov, 2011 | Pubmed ID: 21998326
ARC15105 is a potent antagonist of von Willebrand factor mediated platelet activation and adhesion.
Arteriosclerosis, thrombosis, and vascular biology Apr, 2012 | Pubmed ID: 22282355
Serotonin antagonism improves platelet inhibition in clopidogrel low-responders after coronary stent placement: an in vitro pilot study.
PloS one , 2012 | Pubmed ID: 22384279
Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice.
Blood Feb, 2013 | Pubmed ID: 23243271
Production of serotonin by tryptophan hydroxylase 1 and release via platelets contribute to allergic airway inflammation.
American journal of respiratory and critical care medicine Mar, 2013 | Pubmed ID: 23328530
Lack of tryptophan hydroxylase-1 in mice results in gait abnormalities.
PloS one , 2013 | Pubmed ID: 23516593
[Prevention of recurrent thromboembolisms: WARFASA (aspirin for the prevention of recurrent venous thromboembolism - the Warfarin and Aspirin Study)].
Der Internist Nov, 2013 | Pubmed ID: 24045645
A novel hollow and perforated flexible wire allows the safe and effective local application of thrombolytic therapy in a mouse model of deep vein thrombosis.
Journal of thrombosis and thrombolysis May, 2014 | Pubmed ID: 24163054
Acute fluoxetine treatment induces slow rolling of leukocytes on endothelium in mice.
PloS one , 2014 | Pubmed ID: 24520366
Dual-contrast molecular imaging allows noninvasive characterization of myocardial ischemia/reperfusion injury after coronary vessel occlusion in mice by magnetic resonance imaging.
Circulation Aug, 2014 | Pubmed ID: 24951772
Immune functions of platelets.
Thrombosis and haemostasis Oct, 2014 | Pubmed ID: 25209670
Platelet serotonin modulates immune functions.
Hamostaseologie , 2016 | Pubmed ID: 25693763
HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi.
Thrombosis and haemostasis Nov, 2015 | Pubmed ID: 26202300
Clinical potential of vorapaxar in cardiovascular risk reduction in patients with atherosclerosis.
Therapeutics and clinical risk management , 2015 | Pubmed ID: 26346960
Platelet-neutrophil complex formation-a detailed in vitro analysis of murine and human blood samples.
Journal of leukocyte biology 05, 2016 | Pubmed ID: 26578648
Hsp70 preventing thrombosis: benefit without burden?
Cardiovascular research 06, 2016 | Pubmed ID: 27097649
Acute exposure to air pollution particulate matter aggravates experimental myocardial infarction in mice by potentiating cytokine secretion from lung macrophages.
Basic research in cardiology 07, 2016 | Pubmed ID: 27240856
Rescue of Cytokine Storm Due to HLH by Hemoadsorption in a CTLA4-Deficient Patient.
Journal of clinical immunology Apr, 2017 | Pubmed ID: 28265964
Impact of Thrombolytic Therapy on the Long-Term Outcome of Intermediate-Risk Pulmonary Embolism.
Journal of the American College of Cardiology Mar, 2017 | Pubmed ID: 28335835
The mitochondria-targeting peptide elamipretide diminishes circulating HtrA2 in ST-segment elevation myocardial infarction.
European heart journal. Acute cardiovascular care May, 2017 | Pubmed ID: 28534645
Resting limb muscle perfusion during inspiratory muscle loading in hypoxia and normoxia.
Respiratory physiology & neurobiology 10, 2017 | Pubmed ID: 28625661
Influence of low-flow time on survival after extracorporeal cardiopulmonary resuscitation (eCPR).
Critical care (London, England) Jun, 2017 | Pubmed ID: 28637497
The Effects of Serotonin in Immune Cells.
Frontiers in cardiovascular medicine , 2017 | Pubmed ID: 28775986
Chip-based digital PCR as a novel detection method for quantifying microRNAs in acute myocardial infarction patients.
Acta pharmacologica Sinica Nov, 2017 | Pubmed ID: 29188800
Dabigatran after Short Heparin Anticoagulation for Acute Intermediate-Risk Pulmonary Embolism: Rationale and Design of the Single-Arm PEITHO-2 Study.
Thrombosis and haemostasis 12, 2017 | Pubmed ID: 29212130
Means for Transport in Patients After Remote Extracorporeal Membrane Oxygenation Implantation.
Air medical journal Jan - Feb, 2018 | Pubmed ID: 29332777
A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense.
Nature communications 02, 2018 | Pubmed ID: 29410422
Isoflurane or propofol sedation in patients with targeted temperature management after cardiopulmonary resuscitation: A single center study.
Journal of critical care Jun, 2018 | Pubmed ID: 29413721
A Functional Relevance of the Anaphylatoxin Receptor C3aR for Platelet Function and Arterial Thrombus Formation Marks an Intersection Point Between Innate Immunity and Thrombosis.
Circulation May, 2018 | Pubmed ID: 29802205
Autocrine and paracrine regulatory functions of platelet serotonin.
Platelets Jun, 2018 | Pubmed ID: 29863942
Louise Benning1,
Samuel Robinson1,2,
Marie Follo3,
Lukas Andreas Heger1,
Daniela Stallmann1,
Daniel Duerschmied1,
Christoph Bode1,
Ingo Ahrens1,4,
Marcus Hortmann1
1Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg,
2Department of Medicine, Monash University,
3Department of Medicine I, Lighthouse Core Facility, Medical Center, University of Freiburg,
4Department of Cardiology, Augustinerinnen Hospital, Academic Teaching Hospital, University of Cologne
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