Christopher T. Capaldo

Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6.

Zonula occludens-1 function in the assembly of tight junctions in Madin-Darby canine kidney epithelial cells.

Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells.

JAM-A regulates permeability and inflammation in the intestine in vivo.

Annexin A1 regulates intestinal mucosal injury, inflammation, and repair.

Cytokine regulation of tight junctions.

Junctional adhesion molecule A interacts with Afadin and PDZ-GEF2 to activate Rap1A, regulate beta1 integrin levels, and enhance cell migration.

Dkk-1 inhibits intestinal epithelial cell migration by attenuating directional polarization of leading edge cells.

Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium.

Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways.

JAM-A regulates epithelial proliferation through Akt/β-catenin signalling.

Tight function zonula occludens-3 regulates cyclin D1-dependent cell proliferation.

Regulation of epithelial proliferation by tight junction proteins.

Epithelial adhesive junctions.

Proinflammatory cytokine-induced tight junction remodeling through dynamic self-assembly of claudins.

Claudin switching: Physiological plasticity of the Tight Junction.