Angela Wandinger-Ness

Altered trafficking and epithelial cell polarity in disease.

Rab proteins and endocytic trafficking: potential targets for therapeutic intervention.

Human VPS34 and p150 are Rab7 interacting partners.

A polycystin-1 multiprotein complex is disrupted in polycystic kidney disease cells.

Clustering and redistribution of late endocytic compartments in response to Helicobacter pylori vacuolating toxin.

The proteasome alpha-subunit XAPC7 interacts specifically with Rab7 and late endosomes.

Progesterone receptor isoform identification and subcellular localization in endometrial cancer.

Mispolarization of desmosomal proteins and altered intercellular adhesion in autosomal dominant polycystic kidney disease.

A polycystin multiprotein complex constitutes a cholesterol-containing signalling microdomain in human kidney epithelia.

Interaction and functional analyses of human VPS34/p150 phosphatidylinositol 3-kinase complex with Rab7.

Functional analyses and interaction of the XAPC7 proteasome subunit with Rab7.

Vesicular trafficking of tyrosine kinase receptors and associated proteins in the regulation of signaling and vascular function.

Glutathione-S-transferase-green fluorescent protein fusion protein reveals slow dissociation from high site density beads and measures free GSH.

Human ADPKD primary cyst epithelial cells with a novel, single codon deletion in the PKD1 gene exhibit defective ciliary polycystin localization and loss of flow-induced Ca2+ signaling.

Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins.

Myotubularin lipid phosphatase binds the hVPS15/hVPS34 lipid kinase complex on endosomes.

Rab GTPases at a glance.

Sequential actions of myotubularin lipid phosphatases regulate endosomal PI(3)P and growth factor receptor trafficking.

Flow cytometry for real-time measurement of guanine nucleotide binding and exchange by Ras-like GTPases.

Caveolin-1-dependent infectious entry of human papillomavirus type 31 in human keratinocytes proceeds to the endosomal pathway for pH-dependent uncoating.

Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cells.

Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay.

Receptor protein tyrosine phosphatases are novel components of a polycystin complex.

Rab7 mutants associated with Charcot-Marie-Tooth disease exhibit enhanced NGF-stimulated signaling.

Adult human CD133/1(+) kidney cells isolated from papilla integrate into developing kidney tubules.

Ectopic expression of cadherin 8 is sufficient to cause cyst formation in a novel 3D collagen matrix renal tubule culture.

A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1.

Differential downregulation of e-cadherin and desmoglein by epidermal growth factor.

Drug Repurposing from an Academic Perspective.

A competitive nucleotide binding inhibitor: in vitro characterization of Rab7 GTPase inhibition.

Bacterial pathogens commandeer Rab GTPases to establish intracellular niches.

Rab7 mutants associated with Charcot-Marie-Tooth disease cause delayed growth factor receptor transport and altered endosomal and nuclear signaling.

Characterization of a Cdc42 protein inhibitor and its use as a molecular probe.

A telomerase immortalized human proximal tubule cell line with a truncation mutation (Q4004X) in polycystin-1.

Rapid parallel flow cytometry assays of active GTPases using effector beads.

Meeting report - Arf and Rab family G proteins.

OFD1 and flotillins are integral components of a ciliary signaling protein complex organized by polycystins in renal epithelia and odontoblasts.

Rab proteins and the compartmentalization of the endosomal system.

Quantitative bead-based flow cytometry for assaying Rab7 GTPase interaction with the Rab-interacting lysosomal protein (RILP) effector protein.

Dual-purpose bioreactors to monitor non-invasive physical and biochemical markers of kidney and liver scaffold recellularization.

A novel pharmacologic activity of ketorolac for therapeutic benefit in ovarian cancer patients.

R-ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis.