Center for Molecular Oncology,
Barts Cancer Institute,
Centre for Molecular Oncology,
Center for Molecular Oncology, Barts Cancer Institute,
Centre for Molecular Oncology, Barts Cancer Institute
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Novel immunocompetent murine tumor models for the assessment of replication-competent oncolytic adenovirus efficacy.
Molecular therapy : the journal of the American Society of Gene Therapy Sep, 2003 | Pubmed ID: 12946314
E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models.
Nature biotechnology Nov, 2003 | Pubmed ID: 14555956
Quantitative imaging of Na/I symporter transgene expression using positron emission tomography in the living animal.
Molecular therapy : the journal of the American Society of Gene Therapy Mar, 2004 | Pubmed ID: 15006611
An E1B-19 kDa gene deletion mutant adenovirus demonstrates tumor necrosis factor-enhanced cancer selectivity and enhanced oncolytic potency.
Molecular therapy : the journal of the American Society of Gene Therapy Jun, 2004 | Pubmed ID: 15194046
Interleukin-1beta and tumour necrosis factor-alpha promote the transformation of human immortalised mesothelial cells by erionite.
International journal of oncology Jul, 2004 | Pubmed ID: 15202003
Noninvasive imaging of the transcriptional activities of human telomerase promoter fragments in mice.
Cancer research Jul, 2004 | Pubmed ID: 15256462
A novel assay to assess primary human cancer infectibility by replication-selective oncolytic adenoviruses.
Clinical cancer research : an official journal of the American Association for Cancer Research Jan, 2005 | Pubmed ID: 15671566
Virus-associated RNA I-deleted adenovirus, a potential oncolytic agent targeting EBV-associated tumors.
Cancer research Feb, 2005 | Pubmed ID: 15735041
Activity of the adenoviral E1A deletion mutant dl922-947 in ovarian cancer: comparison with E1A wild-type viruses, bioluminescence monitoring, and intraperitoneal delivery in icodextrin.
Cancer research Jan, 2006 | Pubmed ID: 16424034
Expression of the IAP protein family is dysregulated in pancreatic cancer cells and is important for resistance to chemotherapy.
International journal of cancer Jun, 2007 | Pubmed ID: 17311258
Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963.
The Journal of clinical investigation Nov, 2007 | Pubmed ID: 17965776
Targeting of interferon-beta to produce a specific, multi-mechanistic oncolytic vaccinia virus.
PLoS medicine Dec, 2007 | Pubmed ID: 18162040
Enhancing poxvirus oncolytic effects through increased spread and immune evasion.
Cancer research Apr, 2008 | Pubmed ID: 18381410
CEACAM6 attenuates adenovirus infection by antagonizing viral trafficking in cancer cells.
The Journal of clinical investigation Jun, 2009 | Pubmed ID: 19411761
Lister strain of vaccinia virus armed with endostatin-angiostatin fusion gene as a novel therapeutic agent for human pancreatic cancer.
Gene therapy Oct, 2009 | Pubmed ID: 19587709
Lister strain vaccinia virus, a potential therapeutic vector targeting hypoxic tumours.
Gene therapy Feb, 2010 | Pubmed ID: 19890355
Combination of anti-angiogenic therapy and virotherapy: arming oncolytic viruses with anti-angiogenic genes.
Current opinion in molecular therapeutics Dec, 2009 | Pubmed ID: 20072943
Oncolytic Viruses for Cancer Therapy: Overcoming the Obstacles.
Viruses Jan, 2010 | Pubmed ID: 20543907
PRSS3 promotes tumour growth and metastasis of human pancreatic cancer.
Gut Nov, 2010 | Pubmed ID: 20947888
Lister vaccine strain of vaccinia virus armed with the endostatin-angiostatin fusion gene: an oncolytic virus superior to dl1520 (ONYX-015) for human head and neck cancer.
Human gene therapy Sep, 2011 | Pubmed ID: 21361787
Modification of the early gene enhancer-promoter improves the oncolytic potency of adenovirus 11.
Molecular therapy : the journal of the American Society of Gene Therapy Feb, 2012 | Pubmed ID: 22086234
Systemic delivery of oncolytic viruses: hopes and hurdles.
Advances in virology , 2012 | Pubmed ID: 22400027
A novel therapeutic regimen to eradicate established solid tumors with an effective induction of tumor-specific immunity.
Clinical cancer research : an official journal of the American Association for Cancer Research Dec, 2012 | Pubmed ID: 23091113
Vascular endothelial growth factor A promotes vaccinia virus entry into host cells via activation of the Akt pathway.
Journal of virology Mar, 2013 | Pubmed ID: 23269798
Update on oncolytic viral therapy - targeting angiogenesis.
OncoTargets and therapy , 2013 | Pubmed ID: 23940420
STAT1 interaction with E3-14.7K in monocytes affects the efficacy of oncolytic adenovirus.
Journal of virology Feb, 2014 | Pubmed ID: 24335311
A vaccinia virus armed with interleukin-10 is a promising therapeutic agent for treatment of murine pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Jan, 2015 | Pubmed ID: 25416195
Efficiently editing the vaccinia virus genome by using the CRISPR-Cas9 system.
Journal of virology May, 2015 | Pubmed ID: 25741005
A novel compound WISP3 mutation in a Chinese family with progressive pseudorheumatoid dysplasia.
Gene Jun, 2015 | Pubmed ID: 25794430
Pharmacological Inhibition of β3 Integrin Reduces the Inflammatory Toxicities Caused by Oncolytic Adenovirus without Compromising Anticancer Activity.
Cancer research Jul, 2015 | Pubmed ID: 25977332
New role of Interleukin-10 in enhancing the antitumor efficacy of oncolytic vaccinia virus for treatment of pancreatic cancer.
Oncoimmunology Sep, 2015 | Pubmed ID: 26405610
A marker-free system for highly efficient construction of vaccinia virus vectors using CRISPR Cas9.
Molecular therapy. Methods & clinical development , 2015 | Pubmed ID: 26417609
Vaccinia virus, a promising new therapeutic agent for pancreatic cancer.
Immunotherapy , 2015 | Pubmed ID: 26595180
CRISPR-Cas9 as a Powerful Tool for Efficient Creation of Oncolytic Viruses.
Viruses Mar, 2016 | Pubmed ID: 26959050
The efficacy of oncolytic adenovirus is mediated by T cell responses against virus and tumor in Syrian hamster model.
Clinical cancer research : an official journal of the American Association for Cancer Research Jul, 2016 | Pubmed ID: 27435398
Haploinsufficiency of Hand1 improves mice survival after acute myocardial infarction through preventing cardiac rupture.
Biochemical and biophysical research communications Sep, 2016 | Pubmed ID: 27601324
Genomic Variations in Pancreatic Cancer and Potential Opportunities for Development of New Approaches for Diagnosis and Treatment.
International journal of molecular sciences Jun, 2017 | Pubmed ID: 28587243
Oncolytic Viruses-Interaction of Virus and Tumor Cells in the Battle to Eliminate Cancer.
Frontiers in oncology , 2017 | Pubmed ID: 28944214
Correction for Spurrell et al., "STAT1 Interaction with E3-14.7K in Monocytes Affects the Efficacy of Oncolytic Adenovirus".
Journal of virology Oct, 2017 | Pubmed ID: 28956778
Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent.
Nature communications Nov, 2017 | Pubmed ID: 29123084
1Center for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London,
2Sino-British Research Centre for Molecular Oncology, National Center for International Research in Cell and Gene Therapy, Zhengzhou University,
3School of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University
Rong Li*,1,
Jinxin Miao*,1,2,
Zhiqiang Fan1,
SeokHwan Song3,
Il-keun Kong3,4,
Yaohe Wang2,5,
Zhongde Wang1
1Department of Animal, Dairy, and Veterinary Sciences, Utah State University,
2National Centre for International Research in Cell and Gene Therapy, Sino-British Research Centre, School of Basic Medical Sciences, Zhengzhou University,
3Department of Animal Science Division of Applied Life Science (BK21 Plus), Gyeongsang National University,
4Institute of Agriculture and Life Science, Gyeongsang National University,
5Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London
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