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Carilion Research Institute,
Carilion School of Medicine,
Department of Biological Sciences
Gregorio Valdez has not added Biography.
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Pincher, a pinocytic chaperone for nerve growth factor/TrkA signaling endosomes.
The Journal of cell biology May, 2002 | Pubmed ID: 12011113
The mammalian exocyst, a complex required for exocytosis, inhibits tubulin polymerization.
The Journal of biological chemistry Aug, 2004 | Pubmed ID: 15205466
A neurotrophin signaling cascade coordinates sympathetic neuron development through differential control of TrkA trafficking and retrograde signaling.
Cell Jul, 2004 | Pubmed ID: 15260993
Pincher-mediated macroendocytosis underlies retrograde signaling by neurotrophin receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2005 | Pubmed ID: 15917464
Trk-signaling endosomes are generated by Rac-dependent macroendocytosis.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2007 | Pubmed ID: 17640889
Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction.
The Journal of cell biology Sep, 2008 | Pubmed ID: 18794334
Identification of a developmentally regulated pathway of membrane retrieval in neuronal growth cones.
Journal of cell science Nov, 2008 | Pubmed ID: 18940911
Podosomes are present in a postsynaptic apparatus and participate in its maturation.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2009 | Pubmed ID: 19822767
MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice.
Science (New York, N.Y.) Dec, 2009 | Pubmed ID: 20007902
Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2010 | Pubmed ID: 20679195
Presynaptic calcium channels and α3-integrins are complexed with synaptic cleft laminins, cytoskeletal elements and active zone components.
Journal of neurochemistry Nov, 2010 | Pubmed ID: 20731762
Trk retrograde signaling requires persistent, Pincher-directed endosomes.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2011 | Pubmed ID: 21187387
Shared resistance to aging and ALS in neuromuscular junctions of specific muscles.
PloS one , 2012 | Pubmed ID: 22485182
Agrin and synaptic laminin are required to maintain adult neuromuscular junctions.
PloS one , 2012 | Pubmed ID: 23056392
The role of muscle microRNAs in repairing the neuromuscular junction.
PloS one , 2014 | Pubmed ID: 24664281
EvoCor: a platform for predicting functionally related genes using phylogenetic and expression profiles.
Nucleic acids research Jul, 2014 | Pubmed ID: 24848012
Degeneration of proprioceptive sensory nerve endings in mice harboring amyotrophic lateral sclerosis-causing mutations.
The Journal of comparative neurology Dec, 2015 | Pubmed ID: 26136049
Virginia Tech
William Dalkin1,2,
Thomas Taetzsch1,
Gregorio Valdez1,2,3
1Carilion Research Institute, Virginia Tech,
2Carilion School of Medicine, Virginia Tech,
3Department of Biological Sciences, Virginia Tech
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