Mehmet Toner

Beneficial effect of microinjected trehalose on the cryosurvival of human oocytes.

Metabolic pre-conditioning of cultured cells in physiological levels of insulin: generating resistance to the lipid-accumulating effects of plasma in hepatocytes.

Storage and translational issues in reparative medicine.

Storage and translational issues in reparative medicine: breakout session summary.

Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device.

Antiproteolytic action of insulin in burn-injured rats.

Bioartificial liver process monitoring and control systems with integrated systems capability.

A microfabrication-based dynamic array cytometer.

Cryopreservation of fetal skin is improved by extracellular trehalose.

The glass transition temperature of mixtures of trehalose and hydroxyethyl starch.

Interferon gamma modulates trauma-induced muscle wasting and immune dysfunction.

Overview of the Alliance for Cellular Signaling.

Osmometric behavior of mouse oocytes in the presence of different intracellular sugars.

Desiccation tolerance of spermatozoa dried at ambient temperature: production of fetal mice.

Influence of insulin therapy on burn wound healing in rats.

Measurement of trehalose loading of mammalian cells porated with a metal-actuated switchable pore.

Bioengineering of liver assist devices.

Quantitative microinjection of trehalose into mouse oocytes and zygotes, and its effect on development.

Efficacy of an extracorporeal flat-plate bioartificial liver in treating fulminant hepatic failure.

Long-term function of cryopreserved rat hepatocytes in a coculture system.

Cryopreservation of stem cells using trehalose: evaluation of the method using a human hematopoietic cell line.

Dynamic gene expression profiling using a microfabricated living cell array.

Use of sugars in cryopreserving human oocytes.

Single-cell chemical lysis in picoliter-scale closed volumes using a microfabricated device.

Hepatic tissue engineering for adjunct and temporary liver support: critical technologies.

Continuous flow microfluidic device for rapid erythrocyte lysis.

The influence of microtextured basal lamina analog topography on keratinocyte function and epidermal organization.

Effect of flow and surface conditions on human lymphocyte isolation using microfluidic chambers.

Development of a microfabricated cytometry platform for characterization and sorting of individual leukocytes.

Cryopreservation of isolated primary rat hepatocytes: enhanced survival and long-term hepatospecific function.

Cryopreservation of starfish oocytes.

Analysis of desiccation and vitrification characteristics of carbohydrate films by shear-wave resonators.

Application of genome-wide expression analysis to human health and disease.

Microfabricated grooved substrates as platforms for bioartificial liver reactors.

Designing a hepatocellular microenvironment with protein microarraying and poly(ethylene glycol) photolithography.

Progressive elimination of microinjected trehalose during mouse embryonic development.

Mouse sperm desiccated and stored in trehalose medium without freezing.

Isothermal desiccation and vitrification kinetics of trehalose-dextran solutions.

Blood-on-a-chip.

Enrichment using antibody-coated microfluidic chambers in shear flow: model mixtures of human lymphocytes.

Trehalose loading through the mitochondrial permeability transition pore enhances desiccation tolerance in rat liver mitochondria.

Selective enhancement of cytochrome p-450 activity in rat hepatocytes by in vitro heat shock.

Thermal characterization of Nakagata's mouse sperm freezing protocol.

Trehalose uptake through P2X7 purinergic channels provides dehydration protection.

Microfluidic diffusive filter for apheresis (leukapheresis).

Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients.

Murine B16 melanomas expressing high levels of the chemokine stromal-derived factor-1/CXCL12 induce tumor-specific T cell chemorepulsion and escape from immune control.

Cell handling using microstructured membranes.

Cryo-injury and biopreservation.

Nonmetabolizable glucose compounds impart cryotolerance to primary rat hepatocytes.

Antiproteolytic action of orally delivered insulin using pH-responsive hydrogels in a rat burn model.

Universal microfluidic gradient generator.

Magnetically and biologically active bead-patterned hydrogels.

Size-based microfluidic enrichment of neonatal rat cardiac cell populations.

Treatment of fulminant hepatic failure in rats using a bioartificial liver device containing porcine hepatocytes producing interleukin-1 receptor antagonist.

Liver-specific functional studies in a microfluidic array of primary mammalian hepatocytes.

Panning of multiple subsets of leukocytes on antibody-decorated poly(ethylene) glycol-coated glass slides.

Polyelectrolyte nano-scaffolds for the design of layered cellular architectures.

Microfluidic isolation of leukocytes from whole blood for phenotype and gene expression analysis.

3-O-methyl-D-glucose improves desiccation tolerance of keratinocytes.

Oxygen uptake rates and liver-specific functions of hepatocyte and 3T3 fibroblast co-cultures.

A bioartificial liver device secreting interleukin-1 receptor antagonist for the treatment of hepatic failure in rats.

A high-throughput microfluidic real-time gene expression living cell array.

A microfluidic device for practical label-free CD4(+) T cell counting of HIV-infected subjects.

Multifunctional encoded particles for high-throughput biomolecule analysis.

Patterned co-culture of primary hepatocytes and fibroblasts using polyelectrolyte multilayer templates.

A microchip approach for practical label-free CD4+ T-cell counting of HIV-infected subjects in resource-poor settings.

Elevated hepatocyte-specific functions in fetal rat hepatocytes co-cultured with adult rat hepatocytes.

Engineering complex tissues.

Cell detection and counting through cell lysate impedance spectroscopy in microfluidic devices.

Long-term storage of mouse spermatozoa after evaporative drying.

Radial flow hepatocyte bioreactor using stacked microfabricated grooved substrates.

Microfabrication-based modulation of embryonic stem cell differentiation.

Osmotic selection of human mesenchymal stem/progenitor cells from umbilical cord blood.

Thermal performance of quartz capillaries for vitrification.

Phenotypic analysis of C57BL/6J and FVB/NJ mice generated using evaporatively dried spermatozoa.

Role of trehalose in prevention of giant vesicle adsorption and encapsulated solute leakage in anhydrobiotic preservation.

Continuous inertial focusing, ordering, and separation of particles in microchannels.

Polar stimulation and constrained cell migration in microfluidic channels.

Microfluidic flow-encoded switching for parallel control of dynamic cellular microenvironments.

Isolation of rare circulating tumour cells in cancer patients by microchip technology.

Invention, innovation, entrepreneurship in academic medical centers.

Equilibrium separation and filtration of particles using differential inertial focusing.

Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients.

Elastomeric microchip electrospray emitter for stable cone-jet mode operation in the nanoflow regime.

Rotationally oscillating drill (Ros-Drill) for mouse ICSI without using mercury.

Vitrification by ultra-fast cooling at a low concentration of cryoprotectants in a quartz micro-capillary: a study using murine embryonic stem cells.

Cell-cell interaction modulates neuroectodermal specification of embryonic stem cells.

Desiccation kinetics and biothermodynamics of glass forming trehalose solutions in thin films.

Enhanced differentiation of embryonic stem cells using co-cultivation with hepatocytes.

'Living cantilever arrays' for characterization of mass of single live cells in fluids.

Detection of mutations in EGFR in circulating lung-cancer cells.

Microflow and crack formation patterns in drying sessile droplets of liposomes suspended in trehalose solutions.

Controlled encapsulation of single-cells into monodisperse picolitre drops.

Successful cryopreservation of mouse oocytes by using low concentrations of trehalose and dimethylsulfoxide.

Neutrophil migration assay from a drop of blood.

Microvortex for focusing, guiding and sorting of particles.

Rapid appearance of resolvin precursors in inflammatory exudates: novel mechanisms in resolution.

Stop-flow lithography for the production of shape-evolving degradable microgel particles.

Occurrence of mitochondria-targeted Late Embryogenesis Abundant (LEA) gene in animals increases organelle resistance to water stress.

The CTC-chip: an exciting new tool to detect circulating tumor cells in lung cancer patients.

High-throughput single cell arrays as a novel tool in biopreservation.

Desiccation tolerance in bovine sperm: a study of the effect of intracellular sugars and the supplemental roles of an antioxidant and a chelator.

Comparison between ideal and nonideal solution models for single-cell cryopreservation protocols.

Further optimization of mouse spermatozoa evaporative drying techniques.

Particle segregation and dynamics in confined flows.

Enhancing the performance of a point-of-care CD4+ T-cell counting microchip through monocyte depletion for HIV/AIDS diagnostics.

Adaptive-control model for neutrophil orientation in the direction of chemical gradients.

Nucleation and solidification in static arrays of monodisperse drops.

Chemical gradient-mediated melting curve analysis for genotyping of SNPs.

Dynamic effect of heat shock pretreatment on apoptotic responses to TNF-alpha in liver cells.

High throughput single cell bioinformatics.

A robust electrical microcytometer with 3-dimensional hydrofocusing.

Concentration and purification of human immunodeficiency virus type 1 virions by microfluidic separation of superparamagnetic nanoparticles.

Spontaneous migration of cancer cells under conditions of mechanical confinement.

Genome-wide transcriptome analysis of 150 cell samples.

Surface topography induces 3D self-orientation of cells and extracellular matrix resulting in improved tissue function.

Layered patterning of hepatocytes in co-culture systems using microfabricated stencils.

Concentration of glycerol in aqueous microdroplets by selective removal of water.

Ultra-rapid vitrification of mouse oocytes in low cryoprotectant concentrations.

Microfluidic isolation and transcriptome analysis of serum microvesicles.

MYC regulation of a "poor-prognosis" metastatic cancer cell state.

A study of the effect of sorbitol on osmotic tolerance during partial desiccation of bovine sperm.

Particle focusing in staged inertial microfluidic devices for flow cytometry.

Isolation and characterization of circulating tumor cells from patients with localized and metastatic prostate cancer.

Analysis of factorial time-course microarrays with application to a clinical study of burn injury.

Metabolic preconditioning of cells with AICAR-riboside: improved cryopreservation and cell-type specific impacts on energetics and proliferation.

Controlled induction of distributed microdeformation in wounded tissue via a microchamber array dressing.

Directional decisions during neutrophil chemotaxis inside bifurcating channels.

Burn injury reduces neutrophil directional migration speed in microfluidic devices.

Clinical microfluidics for neutrophil genomics and proteomics.

Differential inertial focusing of particles in curved low-aspect-ratio microchannels.

Isolation of circulating tumor cells using a microvortex-generating herringbone-chip.

LEA proteins during water stress: not just for plants anymore.

A microfabricated electrical differential counter for the selective enumeration of CD4+ T lymphocytes.

A spin-drying technique for lyopreservation of mammalian cells.

Circulating tumor cells: approaches to isolation and characterization.

Metabolic restructuring during energy-limited states: insights from Artemia franciscana embryos and other animals.

Spatially Invariant Vector Quantization: A pattern matching algorithm for multiple classes of image subject matter including pathology.

Nanoporous elements in microfluidics for multiscale manipulation of bioparticles.

A 3D aligned microfibrous myocardial tissue construct cultured under transient perfusion.

Squishy non-spherical hydrogel microparticles.

Computer aided diagnostic tools aim to empower rather than replace pathologists: Lessons learned from computational chess.

Microfluidic proportional flow controller.

Controlled loading of cryoprotectants (CPAs) to oocyte with linear and complex CPA profiles on a microfluidic platform.

Microfluidics-based capture of human neutrophils for expression analysis in blood and bronchoalveolar lavage.

Cryopreservation of spin-dried mammalian cells.

Specific pathogen detection using bioorthogonal chemistry and diagnostic magnetic resonance.

On a chip.

Trehalose transporter from African chironomid larvae improves desiccation tolerance of Chinese hamster ovary cells.

Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility.

Preservation of mouse sperm by convective drying and storing in 3-o-methyl-d-glucose.

Epithelial cell guidance by self-generated EGF gradients.

Clusters of circulating tumor cells traverse capillary-sized vessels.

Controlled ice nucleation using freeze-dried Pseudomonas syringae encapsulated in alginate beads.

Monolithic Chip for High-throughput Blood Cell Depletion to Sort Rare Circulating Tumor Cells.

A highly-occupied, single-cell trapping microarray for determination of cell membrane permeability.

Janus-faced role of water in defining nanostructure of choline chloride/glycerol deep eutectic solvent.

Role of synthetic antifreeze agents in catalyzing ice nucleation.

On-chip oocyte denudation from cumulus-oocyte complexes for assisted reproductive therapy.