M. Luisa Iruela-Arispe

Expression of ADAMTS1 during murine development.

ADAMTS1 cleaves aggrecan at multiple sites and is differentially inhibited by metalloproteinase inhibitors.

Opposing functions of the Ets factors NERF and ELF-1 during chicken blood vessel development.

Visualization of advanced human prostate cancer lesions in living mice by a targeted gene transfer vector and optical imaging.

Selective binding of lectins to embryonic chicken vasculature.

ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165.

ADAMTS1: a matrix metalloprotease with angioinhibitory properties.

Myc-driven murine prostate cancer shares molecular features with human prostate tumors.

Alpha4beta1 integrin mediates selective endothelial cell responses to thrombospondins 1 and 2 in vitro and modulates angiogenesis in vivo.

Thrombospondin modules and angiogenesis.

Whence thrombospondin?

Notch signaling in vascular morphogenesis.

ADAMTS1 proteinase is up-regulated in wounded skin and regulates migration of fibroblasts and endothelial cells.

Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors.

Enhanced inhibition of murine tumor and human breast tumor xenografts using targeted delivery of an antibody-endostatin fusion protein.

Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1.

VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells.

The ever-elusive endothelial progenitor cell: identities, functions and clinical implications.

Proteolytic cleavage of versican during cardiac cushion morphogenesis.

Generation of a mouse for conditional excision of progesterone receptor.

When it comes to blocking lymphatics, it is all a question of time.

My O'Myeloid, a tale of two lineages.

VE-cadherin-CreERT2 transgenic mouse: a model for inducible recombination in the endothelium.

ADAMTS1 mediates the release of antiangiogenic polypeptides from TSP1 and 2.

Vascular abnormalities in mice deficient for the G protein-coupled receptor GPR4 that functions as a pH sensor.

Notch expression patterns in the retina: An eye on receptor-ligand distribution during angiogenesis.

Modulation of protein delivery from modular polymer scaffolds.

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.

Notch signaling in blood vessels: who is talking to whom about what?

Autocrine VEGF signaling is required for vascular homeostasis.

Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis.

Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation.

Cleavage of syndecan-4 by ADAMTS1 provokes defects in adhesion.

Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis.

Regulation of thrombospondin1 by extracellular proteases.

Fate tracing reveals the endothelial origin of hematopoietic stem cells.

Cellular and molecular mechanisms of vascular lumen formation.

Conditional Cre/LoxP strategies for the study of hematopoietic stem cell formation.

The phosphorylation of vascular endothelial growth factor receptor-2 (VEGFR-2) by engineered surfaces with electrostatically or covalently immobilized VEGF.

Time to cut the cord: placental HSCs grow up.

Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy.

Variable inhibition of thrombospondin 1 against liver and lung metastases through differential activation of metalloproteinase ADAMTS1.

Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism.

Extracellular matrix, inflammation, and the angiogenic response.

Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells.

Signaling circuitry in vascular morphogenesis.

The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling.

Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF.

Vascular remodeling of the vitelline artery initiates extravascular emergence of hematopoietic clusters.

When Cre-mediated recombination in mice does not result in protein loss.

Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome.

LUMENating blood vessels.

VEGF internalization is not required for VEGFR-2 phosphorylation in bioengineered surfaces with covalently linked VEGF.

Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane.

Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation.

An essential requirement for β1 integrin in the assembly of extracellular matrix proteins within the vascular wall.

CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis.

Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling.

Recent advances in vascular development.

ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1.

Molecular mechanisms of tumor angiogenesis.

Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.

Selective decline of synaptic protein levels in the frontal cortex of female mice deficient in the extracellular metalloproteinase ADAMTS1.

Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome.

Real-time maps of fluid flow fields in porous biomaterials.

Cellular and molecular regulation of vascular permeability.

Testosterone levels influence mouse fetal Leydig cell progenitors through notch signaling.

Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models.

Reciprocal interactions between endothelial cells and macrophages in angiogenic vascular niches.

Notch1 regulates angio-supportive bone marrow-derived cells in mice: relevance to chemoresistance.

Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy.

Selective suppression of endothelial cytokine production by progesterone receptor.

Tubulogenesis.

β1-integrin is essential for vasoregulation and smooth muscle survival in vivo.

The mouse retina in 3D: quantification of vascular growth and remodeling.

Sox17 is indispensable for acquisition and maintenance of arterial identity.

A ligand-independent VEGFR2 signaling pathway limits angiogenic responses in diabetes.

Hybrid photopatterned enzymatic reaction (HyPER) for in situ cell manipulation.

Progesterone receptor in the vascular endothelium triggers physiological uterine permeability preimplantation.

Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye.

The chicken chorioallantoic membrane model in biology, medicine and bioengineering.

Podosome rosettes precede vascular sprouts in tumour angiogenesis.

Canonical and noncanonical vascular endothelial growth factor pathways: new developments in biology and signal transduction.

Stealing VEGF from thy neighbor.

Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.

Blockade of specific NOTCH ligands: a new promising approach in cancer therapy.

ADAMTS proteases in vascular biology.

State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association.

Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy.

Healing arterial ulcers: Endothelial lining regeneration upon vascular denudation injury.

Macrophage Blockade Using CSF1R Inhibitors Reverses the Vascular Leakage Underlying Malignant Ascites in Late-Stage Epithelial Ovarian Cancer.

Endothelial RhoGEFs: A systematic analysis of their expression profiles in VEGF-stimulated and tumor endothelial cells.

Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis.

Cross-talk between signaling and metabolism in the vasculature.

Notch, lipids, and endothelial cells.

Perivascular Macrophages Limit Permeability.

Cell-type deconvolution with immune pathways identifies gene networks of host defense and immunopathology in leprosy.

Transgenic tomatoes expressing the 6F peptide and ezetimibe prevent diet-induced increases of IFN-β and cholesterol 25-hydroxylase in jejunum.

NOTCH1 is a mechanosensor in adult arteries.

A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis.

Analysis of cardiomyocyte clonal expansion during mouse heart development and injury.

NOTCH regulation of the endothelial cell phenotype.

A multi-step transcriptional cascade underlies vascular regeneration in vivo.

Metastasis of Circulating Tumor Cells: Speed Matters.

Vav3-induced cytoskeletal dynamics contribute to heterotypic properties of endothelial barriers.

Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer.