Department of Molecular,
Cell,
and Developmental Biology,
Department of Molecular, Cell, and Developmental Biology
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Expression of ADAMTS1 during murine development.
Mechanisms of development Jul, 2002 | Pubmed ID: 12049787
ADAMTS1 cleaves aggrecan at multiple sites and is differentially inhibited by metalloproteinase inhibitors.
Biochemical and biophysical research communications Apr, 2002 | Pubmed ID: 12054629
Opposing functions of the Ets factors NERF and ELF-1 during chicken blood vessel development.
Arteriosclerosis, thrombosis, and vascular biology Jul, 2002 | Pubmed ID: 12117724
Visualization of advanced human prostate cancer lesions in living mice by a targeted gene transfer vector and optical imaging.
Nature medicine Aug, 2002 | Pubmed ID: 12134144
Selective binding of lectins to embryonic chicken vasculature.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society May, 2003 | Pubmed ID: 12704207
ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165.
The Journal of biological chemistry Jun, 2003 | Pubmed ID: 12716911
ADAMTS1: a matrix metalloprotease with angioinhibitory properties.
Annals of the New York Academy of Sciences May, 2003 | Pubmed ID: 12814950
Myc-driven murine prostate cancer shares molecular features with human prostate tumors.
Cancer cell Sep, 2003 | Pubmed ID: 14522256
Alpha4beta1 integrin mediates selective endothelial cell responses to thrombospondins 1 and 2 in vitro and modulates angiogenesis in vivo.
Circulation research Mar, 2004 | Pubmed ID: 14699013
Thrombospondin modules and angiogenesis.
The international journal of biochemistry & cell biology Jun, 2004 | Pubmed ID: 15094121
Whence thrombospondin?
Cancer biology & therapy Apr, 2004 | Pubmed ID: 15107618
Notch signaling in vascular morphogenesis.
Current opinion in hematology Jul, 2004 | Pubmed ID: 15314528
ADAMTS1 proteinase is up-regulated in wounded skin and regulates migration of fibroblasts and endothelial cells.
The Journal of biological chemistry Jun, 2005 | Pubmed ID: 15843381
Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors.
The Journal of cell biology May, 2005 | Pubmed ID: 15911882
Enhanced inhibition of murine tumor and human breast tumor xenografts using targeted delivery of an antibody-endostatin fusion protein.
Molecular cancer therapeutics Jun, 2005 | Pubmed ID: 15956253
Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1.
The Journal of biological chemistry Oct, 2005 | Pubmed ID: 16061471
VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells.
Developmental dynamics : an official publication of the American Association of Anatomists Mar, 2006 | Pubmed ID: 16450386
The ever-elusive endothelial progenitor cell: identities, functions and clinical implications.
Pediatric research Apr, 2006 | Pubmed ID: 16549545
Proteolytic cleavage of versican during cardiac cushion morphogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists Aug, 2006 | Pubmed ID: 16691565
Generation of a mouse for conditional excision of progesterone receptor.
Genesis (New York, N.Y. : 2000) Aug, 2006 | Pubmed ID: 16868919
When it comes to blocking lymphatics, it is all a question of time.
The American journal of pathology Aug, 2006 | Pubmed ID: 16877337
My O'Myeloid, a tale of two lineages.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2006 | Pubmed ID: 16924095
VE-cadherin-CreERT2 transgenic mouse: a model for inducible recombination in the endothelium.
Developmental dynamics : an official publication of the American Association of Anatomists Dec, 2006 | Pubmed ID: 17072878
ADAMTS1 mediates the release of antiangiogenic polypeptides from TSP1 and 2.
The EMBO journal Nov, 2006 | Pubmed ID: 17082774
Vascular abnormalities in mice deficient for the G protein-coupled receptor GPR4 that functions as a pH sensor.
Molecular and cellular biology Feb, 2007 | Pubmed ID: 17145776
Notch expression patterns in the retina: An eye on receptor-ligand distribution during angiogenesis.
Gene expression patterns : GEP Feb, 2007 | Pubmed ID: 17161657
Modulation of protein delivery from modular polymer scaffolds.
Biomaterials Apr, 2007 | Pubmed ID: 17184836
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.
Nature Feb, 2007 | Pubmed ID: 17259973
Notch signaling in blood vessels: who is talking to whom about what?
Circulation research Jun, 2007 | Pubmed ID: 17556669
Autocrine VEGF signaling is required for vascular homeostasis.
Cell Aug, 2007 | Pubmed ID: 17719546
Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis.
Developmental cell Feb, 2008 | Pubmed ID: 18267097
Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation.
Nature May, 2008 | Pubmed ID: 18463637
Cleavage of syndecan-4 by ADAMTS1 provokes defects in adhesion.
The international journal of biochemistry & cell biology Apr, 2009 | Pubmed ID: 18775505
Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2008 | Pubmed ID: 18779589
Regulation of thrombospondin1 by extracellular proteases.
Current drug targets Oct, 2008 | Pubmed ID: 18855620
Fate tracing reveals the endothelial origin of hematopoietic stem cells.
Cell stem cell Dec, 2008 | Pubmed ID: 19041779
Cellular and molecular mechanisms of vascular lumen formation.
Developmental cell Feb, 2009 | Pubmed ID: 19217424
Conditional Cre/LoxP strategies for the study of hematopoietic stem cell formation.
Blood cells, molecules & diseases Jul-Aug, 2009 | Pubmed ID: 19250847
The phosphorylation of vascular endothelial growth factor receptor-2 (VEGFR-2) by engineered surfaces with electrostatically or covalently immobilized VEGF.
Biomaterials Sep, 2009 | Pubmed ID: 19540581
Time to cut the cord: placental HSCs grow up.
Cell stem cell Oct, 2009 | Pubmed ID: 19796613
Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy.
Blood Feb, 2010 | Pubmed ID: 20008303
Variable inhibition of thrombospondin 1 against liver and lung metastases through differential activation of metalloproteinase ADAMTS1.
Cancer research Feb, 2010 | Pubmed ID: 20103648
Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism.
Developmental cell Jan, 2010 | Pubmed ID: 20152176
Extracellular matrix, inflammation, and the angiogenic response.
Cardiovascular research May, 2010 | Pubmed ID: 20154066
Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells.
The Journal of cell biology Feb, 2010 | Pubmed ID: 20176926
Signaling circuitry in vascular morphogenesis.
Current opinion in hematology May, 2010 | Pubmed ID: 20216211
The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling.
Developmental cell Jun, 2010 | Pubmed ID: 20627076
Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF.
The American journal of pathology Sep, 2010 | Pubmed ID: 20639457
Vascular remodeling of the vitelline artery initiates extravascular emergence of hematopoietic clusters.
Blood Nov, 2010 | Pubmed ID: 20699440
When Cre-mediated recombination in mice does not result in protein loss.
Genetics Nov, 2010 | Pubmed ID: 20813881
Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome.
Development (Cambridge, England) Dec, 2010 | Pubmed ID: 21062863
LUMENating blood vessels.
Developmental cell Apr, 2011 | Pubmed ID: 21497753
VEGF internalization is not required for VEGFR-2 phosphorylation in bioengineered surfaces with covalently linked VEGF.
Integrative biology : quantitative biosciences from nano to macro Sep, 2011 | Pubmed ID: 21826315
Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane.
Blood Mar, 2012 | Pubmed ID: 22134168
Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation.
Developmental dynamics : an official publication of the American Association of Anatomists Feb, 2012 | Pubmed ID: 22183742
An essential requirement for β1 integrin in the assembly of extracellular matrix proteins within the vascular wall.
Developmental biology May, 2012 | Pubmed ID: 22331032
CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis.
PloS one , 2012 | Pubmed ID: 22363445
Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling.
Developmental cell Mar, 2012 | Pubmed ID: 22387002
Recent advances in vascular development.
Current opinion in hematology May, 2012 | Pubmed ID: 22406825
ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1.
Nature medicine Jun, 2012 | Pubmed ID: 22581286
Molecular mechanisms of tumor angiogenesis.
Genes & cancer Dec, 2011 | Pubmed ID: 22866200
Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.
Blood Oct, 2012 | Pubmed ID: 22919031
Selective decline of synaptic protein levels in the frontal cortex of female mice deficient in the extracellular metalloproteinase ADAMTS1.
PloS one , 2012 | Pubmed ID: 23071766
Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome.
Development (Cambridge, England) Dec, 2012 | Pubmed ID: 23095891
Real-time maps of fluid flow fields in porous biomaterials.
Biomaterials Mar, 2013 | Pubmed ID: 23245922
Cellular and molecular regulation of vascular permeability.
Thrombosis and haemostasis Mar, 2013 | Pubmed ID: 23389236
Testosterone levels influence mouse fetal Leydig cell progenitors through notch signaling.
Biology of reproduction Apr, 2013 | Pubmed ID: 23467742
Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models.
Development (Cambridge, England) Apr, 2013 | Pubmed ID: 23533173
Reciprocal interactions between endothelial cells and macrophages in angiogenic vascular niches.
Experimental cell research Jul, 2013 | Pubmed ID: 23542777
Notch1 regulates angio-supportive bone marrow-derived cells in mice: relevance to chemoresistance.
Blood Jul, 2013 | Pubmed ID: 23690447
Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy.
Cancer research Aug, 2013 | Pubmed ID: 23744837
Selective suppression of endothelial cytokine production by progesterone receptor.
Vascular pharmacology Jul-Aug, 2013 | Pubmed ID: 23747964
Tubulogenesis.
Development (Cambridge, England) Jul, 2013 | Pubmed ID: 23821032
β1-integrin is essential for vasoregulation and smooth muscle survival in vivo.
Arteriosclerosis, thrombosis, and vascular biology Oct, 2013 | Pubmed ID: 23887637
The mouse retina in 3D: quantification of vascular growth and remodeling.
Integrative biology : quantitative biosciences from nano to macro Dec, 2013 | Pubmed ID: 24136100
Sox17 is indispensable for acquisition and maintenance of arterial identity.
Nature communications , 2013 | Pubmed ID: 24153254
A ligand-independent VEGFR2 signaling pathway limits angiogenic responses in diabetes.
Science signaling Jan, 2014 | Pubmed ID: 24399295
Hybrid photopatterned enzymatic reaction (HyPER) for in situ cell manipulation.
Chembiochem : a European journal of chemical biology Jan, 2014 | Pubmed ID: 24399784
Progesterone receptor in the vascular endothelium triggers physiological uterine permeability preimplantation.
Cell Jan, 2014 | Pubmed ID: 24485460
Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye.
EMBO molecular medicine May, 2014 | Pubmed ID: 24705878
The chicken chorioallantoic membrane model in biology, medicine and bioengineering.
Angiogenesis Oct, 2014 | Pubmed ID: 25138280
Podosome rosettes precede vascular sprouts in tumour angiogenesis.
Nature cell biology Oct, 2014 | Pubmed ID: 25271481
Canonical and noncanonical vascular endothelial growth factor pathways: new developments in biology and signal transduction.
Arteriosclerosis, thrombosis, and vascular biology Jan, 2015 | Pubmed ID: 25278287
Stealing VEGF from thy neighbor.
Cell Oct, 2014 | Pubmed ID: 25417099
Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.
Developmental cell Dec, 2014 | Pubmed ID: 25535917
Blockade of specific NOTCH ligands: a new promising approach in cancer therapy.
Cancer discovery Feb, 2015 | Pubmed ID: 25656896
ADAMTS proteases in vascular biology.
Matrix biology : journal of the International Society for Matrix Biology May-Jul, 2015 | Pubmed ID: 25698314
State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association.
Circulation research May, 2015 | Pubmed ID: 25931450
Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy.
Journal of cell science Jun, 2015 | Pubmed ID: 25956888
Healing arterial ulcers: Endothelial lining regeneration upon vascular denudation injury.
Vascular pharmacology Sep, 2015 | Pubmed ID: 26093336
Macrophage Blockade Using CSF1R Inhibitors Reverses the Vascular Leakage Underlying Malignant Ascites in Late-Stage Epithelial Ovarian Cancer.
Cancer research Nov, 2015 | Pubmed ID: 26471360
Endothelial RhoGEFs: A systematic analysis of their expression profiles in VEGF-stimulated and tumor endothelial cells.
Vascular pharmacology Nov, 2015 | Pubmed ID: 26471833
Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis.
The Journal of experimental medicine Nov, 2015 | Pubmed ID: 26552708
Cross-talk between signaling and metabolism in the vasculature.
Vascular pharmacology Aug, 2016 | Pubmed ID: 27291139
Notch, lipids, and endothelial cells.
Current opinion in lipidology Oct, 2016 | Pubmed ID: 27454451
Perivascular Macrophages Limit Permeability.
Arteriosclerosis, thrombosis, and vascular biology Nov, 2016 | Pubmed ID: 27634833
Cell-type deconvolution with immune pathways identifies gene networks of host defense and immunopathology in leprosy.
JCI insight Sep, 2016 | Pubmed ID: 27699251
Transgenic tomatoes expressing the 6F peptide and ezetimibe prevent diet-induced increases of IFN-β and cholesterol 25-hydroxylase in jejunum.
Journal of lipid research Aug, 2017 | Pubmed ID: 28592401
NOTCH1 is a mechanosensor in adult arteries.
Nature communications Nov, 2017 | Pubmed ID: 29158473
A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis.
Cell reports Jan, 2018 | Pubmed ID: 29386109
Analysis of cardiomyocyte clonal expansion during mouse heart development and injury.
Nature communications 02, 2018 | Pubmed ID: 29467410
NOTCH regulation of the endothelial cell phenotype.
Current opinion in hematology May, 2018 | Pubmed ID: 29547401
A multi-step transcriptional cascade underlies vascular regeneration in vivo.
Scientific reports Apr, 2018 | Pubmed ID: 29615716
Metastasis of Circulating Tumor Cells: Speed Matters.
Developmental cell 04, 2018 | Pubmed ID: 29634934
Vav3-induced cytoskeletal dynamics contribute to heterotypic properties of endothelial barriers.
The Journal of cell biology Jun, 2018 | Pubmed ID: 29858212
Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer.
Scientific reports Jun, 2018 | Pubmed ID: 29899427
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