Martin Yarmush

Thermodynamic and kinetic characterization of antisense oligodeoxynucleotide binding to a structured mRNA.

Metabolic pre-conditioning of cultured cells in physiological levels of insulin: generating resistance to the lipid-accumulating effects of plasma in hepatocytes.

Polybrene increases retrovirus gene transfer efficiency by enhancing receptor-independent virus adsorption on target cell membranes.

Advances in proteomic technologies.

Antiproteolytic action of insulin in burn-injured rats.

Bioartificial liver process monitoring and control systems with integrated systems capability.

Long-term stable cultures of rat hepatocytes: an in vitro model to study acute and chronic hepatic inflammation.

Interferon gamma modulates trauma-induced muscle wasting and immune dysfunction.

Metabolic flux analysis of cultured hepatocytes exposed to plasma.

Influence of insulin therapy on burn wound healing in rats.

Bioengineering of liver assist devices.

Application of multivariate analysis to optimize function of cultured hepatocytes.

Metabolic flux analysis of hepatocyte function in hormone- and amino acid-supplemented plasma.

Profiling of dynamic changes in hypermetabolic livers.

Efficacy of an extracorporeal flat-plate bioartificial liver in treating fulminant hepatic failure.

Control analysis of mitochondrial metabolism in intact hepatocytes: effect of interleukin-1beta and interleukin-6.

Metabolic engineering: advances in modeling and intervention in health and disease.

Induction of a hypermetabolic state in cultured hepatocytes by glucagon and H2O2.

Growth factors and nonparenchymal cell conditioned media induce mitogenic responses in stable long-term adult rat hepatocyte cultures.

Charged polymers modulate retrovirus transduction via membrane charge neutralization and virus aggregation.

Identification of optimal classification functions for biological sample and state discrimination from metabolic profiling data.

Technique for expanding the donor liver pool: heat shock preconditioning in a rat fatty liver model.

Dispensable role for interferon-gamma in the burn-induced acute phase response: a proteomic analysis.

Dynamic gene expression profiling using a microfabricated living cell array.

A mouse serum two-dimensional gel map: application to profiling burn injury and infection.

Quantitative dynamics of in vivo bone marrow neutrophil production and egress in response to injury and infection.

Quantitative effects of thermal injury and insulin on the metabolism of the skeletal muscle using the perfused rat hindquarter preparation.

Hepatic tissue engineering for adjunct and temporary liver support: critical technologies.

Insulin concentration during preconditioning mediates the regulation of urea synthesis during exposure to amino acid-supplemented plasma.

Evaluation of an in vitro model of hepatic inflammatory response by gene expression profiling.

Evolution of intrahepatic carbon, nitrogen, and energy metabolism in a D-galactosamine-induced rat liver failure model.

Microfabricated grooved substrates as platforms for bioartificial liver reactors.

Designing a hepatocellular microenvironment with protein microarraying and poly(ethylene glycol) photolithography.

Effects of dehydroepiandrosterone administration on rat hepatic metabolism following thermal injury.

Identification of neutrophil gelatinase-associated lipocalin (NGAL) as a discriminatory marker of the hepatocyte-secreted protein response to IL-1beta: a proteomic analysis.

Immunodepletion of albumin for two-dimensional gel detection of new mouse acute-phase protein and other plasma proteins.

Optimization of reporter cells for expression profiling in a microfluidic device.

Selective enhancement of cytochrome p-450 activity in rat hepatocytes by in vitro heat shock.

Alginate-PLL microencapsulation: effect on the differentiation of embryonic stem cells into hepatocytes.

Liver endothelial cells promote LDL-R expression and the uptake of HCV-like particles in primary rat and human hepatocytes.

Proteomic analysis of altered protein expression in skeletal muscle of rats in a hypermetabolic state induced by burn sepsis.

Heat shock preconditioning inhibits CD4+ T lymphocyte activation in transplanted fatty rat livers.

Modulation of single-chain antibody affinity with temperature-responsive elastin-like polypeptide linkers.

Treatment of fulminant hepatic failure in rats using a bioartificial liver device containing porcine hepatocytes producing interleukin-1 receptor antagonist.

Liver-specific functional studies in a microfluidic array of primary mammalian hepatocytes.

Embryoid body-mediated differentiation of mouse embryonic stem cells along a hepatocyte lineage: insights from gene expression profiles.

Polyelectrolyte nano-scaffolds for the design of layered cellular architectures.

Contribution of gene expression to metabolic fluxes in hypermetabolic livers induced through burn injury and cecal ligation and puncture in rats.

Oxygen uptake rates and liver-specific functions of hepatocyte and 3T3 fibroblast co-cultures.

Development of an array of ion-selective microelectrodes aimed for the monitoring of extracellular ionic activities.

A novel formulation of oxygen-carrying matrix enhances liver-specific function of cultured hepatocytes.

A bioartificial liver device secreting interleukin-1 receptor antagonist for the treatment of hepatic failure in rats.

A high-throughput microfluidic real-time gene expression living cell array.

Integration of technologies for hepatic tissue engineering.

Bioinformatics analysis of the early inflammatory response in a rat thermal injury model.

Patterned co-culture of primary hepatocytes and fibroblasts using polyelectrolyte multilayer templates.

Control of hepatic differentiation via cellular aggregation in an alginate microenvironment.

Integrated energy and flux balance based multiobjective framework for large-scale metabolic networks.

Engineering protein and peptide building blocks for nanotechnology.

Elevated hepatocyte-specific functions in fetal rat hepatocytes co-cultured with adult rat hepatocytes.

A model for normothermic preservation of the rat liver.

Amphipathic peptide-based fusion peptides and immunoconjugates for the targeted ablation of prostate cancer cells.

Radial flow hepatocyte bioreactor using stacked microfabricated grooved substrates.

Microfabrication-based modulation of embryonic stem cell differentiation.

Osmotic selection of human mesenchymal stem/progenitor cells from umbilical cord blood.

Immunomodulation of activated hepatic stellate cells by mesenchymal stem cells.

Mesenchymal stem cell-derived molecules reverse fulminant hepatic failure.

Homogeneous differentiation of hepatocyte-like cells from embryonic stem cells: applications for the treatment of liver failure.

The use of elastin-like polypeptide-polyelectrolyte complexes to control hepatocyte morphology and function in vitro.

Burn-induced immunosuppression: attenuated T cell signaling independent of IFN-gamma- and nitric oxide-mediated pathways.

Activin alters the kinetics of endoderm induction in embryonic stem cells cultured on collagen gels.

A microfluidic bioreactor for increased active retrovirus output.

Microfluidic flow-encoded switching for parallel control of dynamic cellular microenvironments.

Functional modulation of ES-derived hepatocyte lineage cells via substrate compliance alteration.

Three-dimensional primary hepatocyte culture in synthetic self-assembling peptide hydrogel.

Apolipoprotein B-dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin.

Mesenchymal stem cell-derived molecules directly modulate hepatocellular death and regeneration in vitro and in vivo.

Site-directed mutagenesis of the hinge peptide from the hemagglutinin protein: enhancement of the pH-responsive conformational change.

Bone marrow-derived mesenchymal stem cells ameliorate autoimmune enteropathy independently of regulatory T cells.

Vitrification by ultra-fast cooling at a low concentration of cryoprotectants in a quartz micro-capillary: a study using murine embryonic stem cells.

A new technique for primary hepatocyte expansion in vitro.

Cell-cell interaction modulates neuroectodermal specification of embryonic stem cells.

Enhanced differentiation of embryonic stem cells using co-cultivation with hepatocytes.

Steatosis reversibly increases hepatocyte sensitivity to hypoxia-reoxygenation injury.

Moloney murine leukemia virus decay mediated by retroviral reverse transcriptase degradation of genomic RNA.

Gene expression profiling of long-term changes in rat liver following burn injury.

Transient gene delivery for functional enrichment of differentiating embryonic stem cells.

Transcription factor network reconstruction using the living cell array.

Development of an in vitro cell culture model of hepatic steatosis using hepatocyte-derived reporter cells.

Microfluidics and multielectrode array-compatible organotypic slice culture method.

Dissimilar hepatic protein expression profiles during the acute and flow phases following experimental thermal injury.

Recovery of warm ischemic rat liver grafts by normothermic extracorporeal perfusion.

Augmentation of EB-directed hepatocyte-specific function via collagen sandwich and SNAP.

Enrichment of hepatocyte-like cells with upregulated metabolic and differentiated function derived from embryonic stem cells using S-NitrosoAcetylPenicillamine.

Amino acid-mediated heterotypic interaction governs performance of a hepatic tissue model.

High-throughput single cell arrays as a novel tool in biopreservation.

Reversible pH-controlled DNA-binding peptide nanotweezers: an in-silico study.

Long-term superior performance of a stem cell/hepatocyte device for the treatment of acute liver failure.

Living-cell microarrays.

Nest making and oxytocin comparably promote wound healing in isolation reared rats.

Metabolic preconditioning of donor organs: defatting fatty livers by normothermic perfusion ex vivo.

DNA-triggered innate immune responses are propagated by gap junction communication.

Dynamic effect of heat shock pretreatment on apoptotic responses to TNF-alpha in liver cells.

Oxygen-mediated enhancement of primary hepatocyte metabolism, functional polarization, gene expression, and drug clearance.

Stem cells for liver repopulation.

High throughput single cell bioinformatics.

Effects of burn injury on markers of hypermetabolism in rats.

A microfluidic hepatic coculture platform for cell-based drug metabolism studies.

Layered patterning of hepatocytes in co-culture systems using microfabricated stencils.

What came first: fully functional or metabolically mature liver?

The fabrication of low-impedance nanoporous gold multiple-electrode arrays for neural electrophysiology studies.

Adipocyte-derived basement membrane extract with biological activity: applications in hepatocyte functional augmentation in vitro.

Lytic peptide-mediated sensitization of TRAIL-resistant prostate cancer cells to death receptor agonists.

Building and manipulating neural pathways with microfluidics.

An integer programming formulation to identify the sparse network architecture governing differentiation of embryonic stem cells.

Cell delivery: from cell transplantation to organ engineering.

Mesenchymal stem cells: Mechanisms of immunomodulation and homing.

Retinal pigment epithelium differentiation of stem cells: current status and challenges.

Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix.

Soft constraints-based multiobjective framework for flux balance analysis.

Engineering of an hepatic organoid to develop liver assist devices.

Human immune reactivity against liver sinusoidal endothelial cells from GalTα(1,3)GalT-deficient pigs.

Bone marrow mesenchymal stromal cells attenuate organ injury induced by LPS and burn.

Serum starvation improves transient transfection efficiency in differentiating embryonic stem cells.

Metabolic flux determination in perfused livers by mass balance analysis: effect of fasting.

Reactive bone marrow stromal cells attenuate systemic inflammation via sTNFR1.

Tissue-Engineered Model for Real-Time Monitoring of Liver Inflammation.

Impact of co-culture on pancreatic differentiation of embryonic stem cells.

Transcriptional regulation of human and rat hepatic lipid metabolism by the grapefruit flavonoid naringenin: role of PPARalpha, PPARgamma and LXRalpha.

Droplet-based microfluidic platforms for single T cell secretion analysis of IL-10 cytokine.

A mesenchymal stem cell potency assay.

Bone marrow stromal cell transplants prevent experimental enterocolitis and require host CD11b+ splenocytes.

In situ metabolic flux analysis to quantify the liver metabolic response to experimental burn injury.

Ultrasensitive Detection of Low-Abundance Surface-Marker Protein Using Isothermal Rolling Circle Amplification in a Microfluidic Nanoliter Platform.

Self-assembling elastin-like peptides growth factor chimeric nanoparticles for the treatment of chronic wounds.

Ultrasensitive detection of low-abundance surface-marker protein using isothermal rolling circle amplification in a microfluidic nanoliter platform.

Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism.

In situ metabolic flux analysis to quantify the liver metabolic response to experimental burn injury.

Differentiating stem cells into liver.

Neural lineage differentiation of embryonic stem cells within alginate microbeads.

Enhancement of naringenin bioavailability by complexation with hydroxypropoyl-β-cyclodextrin.

In vitro models of traumatic brain injury.

Novel ligands that target the mitochondrial membrane protein mitoNEET.

Subnormothermic Machine Perfusion at Both 20°C and 30°C Recovers Ischemic Rat Livers for Successful Transplantation.

Metabolic profiling based quantitative evaluation of hepatocellular metabolism in presence of adipocyte derived extracellular matrix.

The inflammatory response to double stranded DNA in endothelial cells is mediated by NFκB and TNFα.

Encapsulated mesenchymal stromal cells for in vivo transplantation.

Phenotypic and functional characterization of human bone marrow stromal cells in hollow-fibre bioreactors.

Aire controls mesenchymal stem cell-mediated suppression in chronic colitis.

Suppressive Effects of Interleukin-18 on Liver Function in Rat Liver Allografts.

A novel 3D liver organoid system for elucidation of hepatic glucose metabolism.

Environmental enrichment with nesting material accelerates wound healing in isolation-reared rats.

Optimality and thermodynamics determine the evolution of transcriptional regulatory networks.

Excorporeal Normothermic Machine Perfusion Resuscitates Pig DCD Livers with Extended Warm Ischemia.

Solving medical problems with BioMEMS.

Trehalose transporter from African chironomid larvae improves desiccation tolerance of Chinese hamster ovary cells.

A metabolic index of ischemic injury for perfusion-recovery of cadaveric rat livers.

Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure.