Marco Oldiges

Monitoring and modeling of the reaction dynamics in the valine/leucine synthesis pathway in Corynebacterium glutamicum.

Metabolic flux analysis at ultra short time scale: isotopically non-stationary 13C labeling experiments.

Metabolomics: current state and evolving methodologies and tools.

Influence of L-isoleucine and pantothenate auxotrophy for L-valine formation in Corynebacterium glutamicum revisited by metabolome analyses.

Analysis of amino acids without derivatization in barley extracts by LC-MS-MS.

Metabolic quenching of Corynebacterium glutamicum: efficiency of methods and impact of cold shock.

Modeling metabolic networks in C. glutamicum: a comparison of rate laws in combination with various parameter optimization strategies.

The identification of enzyme targets for the optimization of a valine producing Corynebacterium glutamicum strain using a kinetic model.

Analysing overexpression of L-valine biosynthesis genes in pyruvate-dehydrogenase-deficient Corynebacterium glutamicum.

Importance of NADPH supply for improved L-valine formation in Corynebacterium glutamicum.

Metabolic impact of increased NADH availability in Saccharomyces cerevisiae.

Studies on substrate utilisation in L-valine-producing Corynebacterium glutamicum strains deficient in pyruvate dehydrogenase complex.

Stationary versus non-stationary (13)C-MFA: a comparison using a consistent dataset.

Comparative 13C metabolic flux analysis of pyruvate dehydrogenase complex-deficient, L-valine-producing Corynebacterium glutamicum.

Direct analysis of underivatized amino acids in plant extracts by LC-MS-MS.

Polyketide proofreading by an acyltransferase-like enzyme.

An automated workflow for enhancing microbial bioprocess optimization on a novel microbioreactor platform.

Assessment of robustness against dissolved oxygen/substrate oscillations for C. glutamicum DM1933 in two-compartment bioreactor.

Process inhomogeneity leads to rapid side product turnover in cultivation of Corynebacterium glutamicum.

Application of metabolic engineering for the biotechnological production of L-valine.

Rapid assessment of oxygen transfer impact for Corynebacterium glutamicum.

Standard reporting requirements for biological samples in metabolomics experiments: microbial and in vitro biology experiments.

Bioprocess automation on a Mini Pilot Plant enables fast quantitative microbial phenotyping.

(13)C Tracers for Glucose Degrading Pathway Discrimination in Gluconobacter oxydans 621H.

Automation of a Nile red staining assay enables high throughput quantification of microalgal lipid production.

Design and validation of a parallelized micro-photobioreactor enabling phototrophic bioprocess development at elevated throughput.

Current state and challenges for dynamic metabolic modeling.

Metabolic profile of 1,5-diaminopentane producing Corynebacterium glutamicum under scale-down conditions: Blueprint for robustness to bioreactor inhomogeneities.

Use of a Sec signal peptide library from Bacillus subtilis for the optimization of cutinase secretion in Corynebacterium glutamicum.

Comparative evaluation of phototrophic microtiter plate cultivation against laboratory-scale photobioreactors.

A framework for accelerated phototrophic bioprocess development: integration of parallelized microscale cultivation, laboratory automation and Kriging-assisted experimental design.

Fast and reliable strain characterization of Streptomyces lividans through micro-scale cultivation.

pH fluctuations imperil the robustness of C. glutamicum to short term oxygen limitation.

Laboratory scale photobiotechnology - Current trends and future perspectives.

Automated growth rate determination in high-throughput microbioreactor systems.