Institute of Molecular Biology and Biotechnology
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Imaging of Caenorhabditis elegans neurons by second-harmonic generation and two-photon excitation fluorescence.
Journal of biomedical optics Mar-Apr, 2005 | Pubmed ID: 15910089
Cardiomyocyte necrosis: alternative mechanisms, effective interventions.
Biochimica et biophysica acta Apr, 2007 | Pubmed ID: 17320988
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1.
The EMBO journal May, 2007 | Pubmed ID: 17446862
Protein synthesis and aging: eIF4E and the soma vs. germline distinction.
Cell cycle (Georgetown, Tex.) May, 2007 | Pubmed ID: 17495543
Ageing and the regulation of protein synthesis: a balancing act?
Trends in cell biology May, 2008 | Pubmed ID: 18346894
The effects of p53 on whole organism longevity are mediated by autophagy.
Autophagy Oct, 2008 | Pubmed ID: 18728385
A synaptic DEG/ENaC ion channel mediates learning in C. elegans by facilitating dopamine signalling.
The EMBO journal Dec, 2008 | Pubmed ID: 19037257
Autophagy in Caenorhabditis elegans.
Biochimica et biophysica acta Sep, 2009 | Pubmed ID: 19150634
Cell-specific monitoring of protein synthesis in vivo.
PloS one , 2009 | Pubmed ID: 19234598
The NemaGENETAG initiative: large scale transposon insertion gene-tagging in Caenorhabditis elegans.
Genetica Sep, 2009 | Pubmed ID: 19343510
SUMOylation and cell signalling.
Biotechnology journal Dec, 2009 | Pubmed ID: 19946876
Non-apoptotic cell death in Caenorhabditis elegans.
Developmental dynamics : an official publication of the American Association of Anatomists May, 2010 | Pubmed ID: 20108319
Roles for SUMO modification during senescence.
Advances in experimental medicine and biology , 2010 | Pubmed ID: 20886763
Modeling human diseases in Caenorhabditis elegans.
Biotechnology journal Dec, 2010 | Pubmed ID: 21154667
Correction for specimen movement and rotation errors for in-vivo Optical Projection Tomography.
Biomedical optics express Jul, 2010 | Pubmed ID: 21258448
Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome.
The Journal of cell biology Feb, 2011 | Pubmed ID: 21339330
Cell tracking in live Caenorhabditis elegans embryos via third harmonic generation imaging microscopy measurements.
Journal of biomedical optics Apr, 2011 | Pubmed ID: 21529088
Microscopic optical projection tomography in vivo.
PloS one Apr, 2011 | Pubmed ID: 21559481
Cellular stress response pathways and ageing: intricate molecular relationships.
The EMBO journal May, 2011 | Pubmed ID: 21587205
Autophagy and ageing: insights from invertebrate model organisms.
Ageing research reviews Jan, 2013 | Pubmed ID: 22634332
Embryonic and induced pluripotent stem cell differentiation as a tool in neurobiology.
Biotechnology journal Sep, 2012 | Pubmed ID: 22890755
Calcium homeostasis in aging neurons.
Frontiers in genetics , 2012 | Pubmed ID: 23060904
The contactin RIG-6 mediates neuronal and non-neuronal cell migration in Caenorhabditis elegans.
Developmental biology Jan, 2013 | Pubmed ID: 23123963
Mitophagy in neurodegeneration and aging.
Frontiers in genetics , 2012 | Pubmed ID: 23267366
Oxidative stress and mitochondrial protein quality control in aging.
Journal of proteomics Oct, 2013 | Pubmed ID: 23563202
Metabolic control by target of rapamycin and autophagy during ageing - a mini-review.
Gerontology , 2013 | Pubmed ID: 23594965
GPA-14, a Gα(i) subunit mediates dopaminergic behavioral plasticity in C. elegans.
Behavioral and brain functions : BBF Apr, 2013 | Pubmed ID: 23607404
Crosstalk between apoptosis, necrosis and autophagy.
Biochimica et biophysica acta Dec, 2013 | Pubmed ID: 23770045
Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease.
The EMBO journal Nov, 2013 | Pubmed ID: 24129513
Cellular and molecular longevity pathways: the old and the new.
Trends in endocrinology and metabolism: TEM Apr, 2014 | Pubmed ID: 24388148
Mitochondrial homeostasis: the interplay between mitophagy and mitochondrial biogenesis.
Experimental gerontology Aug, 2014 | Pubmed ID: 24486129
Longevity pathways and memory aging.
Frontiers in genetics , 2014 | Pubmed ID: 24926313
Necrotic cell death in Caenorhabditis elegans.
Methods in enzymology , 2014 | Pubmed ID: 25065889
20S proteasome activation promotes life span extension and resistance to proteotoxicity in Caenorhabditis elegans.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Feb, 2015 | Pubmed ID: 25395451
Protein synthesis as an integral quality control mechanism during ageing.
Ageing research reviews Sep, 2015 | Pubmed ID: 25555680
Unsaturated fatty acids induce non-canonical autophagy.
The EMBO journal Apr, 2015 | Pubmed ID: 25586377
Stress responses during ageing: molecular pathways regulating protein homeostasis.
Methods in molecular biology (Clifton, N.J.) , 2015 | Pubmed ID: 25804759
Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans.
Nature May, 2015 | Pubmed ID: 25896323
Mitochondria, autophagy and age-associated neurodegenerative diseases: New insights into a complex interplay.
Biochimica et biophysica acta Nov, 2015 | Pubmed ID: 25917894
A customized light sheet microscope to measure spatio-temporal protein dynamics in small model organisms.
PloS one , 2015 | Pubmed ID: 26000610
Coupling mitogenesis and mitophagy for longevity.
Autophagy , 2015 | Pubmed ID: 26083448
Iron-Starvation-Induced Mitophagy Mediates Lifespan Extension upon Mitochondrial Stress in C. elegans.
Current biology : CB Jul, 2015 | Pubmed ID: 26144971
FAH domain containing protein 1 (FAHD-1) is required for mitochondrial function and locomotion activity in C. elegans.
PloS one , 2015 | Pubmed ID: 26266933
Interfacing mitochondrial biogenesis and elimination to enhance host pathogen defense and longevity.
Worm Jul-Sep, 2015 | Pubmed ID: 26430570
Enhanced proteasome degradation extends Caenorhabditis elegans lifespan and alleviates aggregation-related pathologies.
Free radical biology & medicine Oct, 2014 | Pubmed ID: 26461298
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Autophagy Jan, 2016 | Pubmed ID: 26799652
18α-Glycyrrhetinic Acid Proteasome Activator Decelerates Aging and Alzheimer's Disease Progression in Caenorhabditis elegans and Neuronal Cultures.
Antioxidants & redox signaling Dec, 2016 | Pubmed ID: 26886723
Caenorhabditis elegans as a model for cancer research.
Molecular & cellular oncology Apr-Jun, 2015 | Pubmed ID: 27308424
Mitophagy: In sickness and in health.
Molecular & cellular oncology Jan, 2016 | Pubmed ID: 27308569
Mitochondrial biogenesis and clearance: a balancing act.
The FEBS journal Jan, 2017 | Pubmed ID: 27462821
Selective and differential interactions of BNN27, a novel C17-spiroepoxy steroid derivative, with TrkA receptors, regulating neuronal survival and differentiation.
Neuropharmacology 12, 2016 | Pubmed ID: 27618740
Differential Protein Distribution between the Nucleus and Mitochondria: Implications in Aging.
Frontiers in genetics , 2016 | Pubmed ID: 27695477
Ectopic fat deposition contributes to age-associated pathology in Caenorhabditis elegans.
Journal of lipid research Jan, 2017 | Pubmed ID: 27884963
Autophagy and the endo/exosomal pathways in health and disease.
Biotechnology journal Jan, 2017 | Pubmed ID: 27976834
Stage dependent nutritional regulation of transgenerational longevity.
Nutrition and healthy aging Oct, 2016 | Pubmed ID: 28035341
Small heat shock proteins in ageing and age-related diseases.
Cell stress & chaperones Jul, 2017 | Pubmed ID: 28074336
The role of SUMOylation in ageing and senescent decline.
Mechanisms of ageing and development Mar, 2017 | Pubmed ID: 28088449
Intracellular Assessment of ATP Levels in Caenorhabditis elegans.
Bio-protocol Dec, 2016 | Pubmed ID: 28194429
Monitoring Autophagic Responses in Caenorhabditis elegans.
Methods in enzymology , 2017 | Pubmed ID: 28237114
Measuring Oxygen Consumption Rate in Caenorhabditis elegans.
Bio-protocol Dec, 2016 | Pubmed ID: 28239622
P-body and Stress Granule Quantification in Caenorhabditis elegans.
Bio-protocol Jan, 2017 | Pubmed ID: 28239624
Assessing Mitochondrial Selective Autophagy in the Nematode Caenorhabditis elegans.
Methods in molecular biology (Clifton, N.J.) , 2017 | Pubmed ID: 28276029
Protein Synthesis Rate Assessment by Fluorescence Recovery after Photobleaching (FRAP).
Bio-protocol Mar, 2017 | Pubmed ID: 28286807
Monitoring Mitophagy During Aging in Caenorhabditis elegans.
Methods in molecular biology (Clifton, N.J.) Mar, 2017 | Pubmed ID: 28324491
In vivo Mitophagy Monitoring in Caenorhabditis elegans to Determine Mitochondrial Homeostasis.
Bio-protocol Apr, 2017 | Pubmed ID: 28405595
Mitophagy and age-related pathologies: Development of new therapeutics by targeting mitochondrial turnover.
Pharmacology & therapeutics Oct, 2017 | Pubmed ID: 28461251
Molecular definitions of autophagy and related processes.
The EMBO journal Jul, 2017 | Pubmed ID: 28596378
Modulation of Autophagy by BDNF Underlies Synaptic Plasticity.
Cell metabolism Jul, 2017 | Pubmed ID: 28683289
Differential adiponectin signalling couples ER stress with lipid metabolism to modulate ageing in C. elegans.
Scientific reports Jul, 2017 | Pubmed ID: 28698593
TEMPORARY REMOVAL: The PMR1 pump in alpha-synuclein toxicity and neurodegeneration.
Neuroscience letters Aug, 2017 | Pubmed ID: 28780169
Caenorhabditis elegans Microinjection.
Bio-protocol Oct, 2017 | Pubmed ID: 29071286
Demonstrating Improved Multiple Transport-Mean-Free-Path Imaging Capabilities of Light Sheet Microscopy in the Quantification of Fluorescence Dynamics.
Biotechnology journal Jan, 2018 | Pubmed ID: 29168308
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Cell death and differentiation Mar, 2018 | Pubmed ID: 29362479
Mitochondrial contributions to neuronal development and function.
Biological chemistry 06, 2018 | Pubmed ID: 29476663
Aspirin Recapitulates Features of Caloric Restriction.
Cell reports 02, 2018 | Pubmed ID: 29490275
Sex-specific regulation of aging in Caenorhabditis elegans.
Aging cell 06, 2018 | Pubmed ID: 29493066
Regulation and Roles of Autophagy at Synapses.
Trends in cell biology 08, 2018 | Pubmed ID: 29731196
Autophagy in Age-Associated Neurodegeneration.
Cells May, 2018 | Pubmed ID: 29734735
Multimodal sensory processing in .
Open biology 06, 2018 | Pubmed ID: 29925633
The Role of Mitophagy in Innate Immunity.
Frontiers in immunology , 2018 | Pubmed ID: 29951054
Novel Insights Into the Anti-aging Role of Mitophagy.
International review of cell and molecular biology , 2018 | Pubmed ID: 30072091
Small heat shock proteins and neurodegeneration: recent developments.
Biomolecular concepts Aug, 2018 | Pubmed ID: 30133417
Mechanisms of mitophagy in cellular homeostasis, physiology and pathology.
Nature cell biology Sep, 2018 | Pubmed ID: 30154567
Hypoxia and Selective Autophagy in Cancer Development and Therapy.
Frontiers in cell and developmental biology , 2018 | Pubmed ID: 30250843
Maintenance of Proteostasis by P Body-Mediated Regulation of eIF4E Availability during Aging in Caenorhabditis elegans.
Cell reports 10, 2018 | Pubmed ID: 30282029
Mitophagy Dynamics in Caenorhabditis elegans.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 30610729
Nucleophagy: from homeostasis to disease.
Cell death and differentiation 03, 2019 | Pubmed ID: 30647432
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Nature neuroscience 03, 2019 | Pubmed ID: 30742114
Mitochondrial maturation drives germline stem cell differentiation in Caenorhabditis elegans.
Cell death and differentiation 02, 2020 | Pubmed ID: 31217501
Mitophagy and Neuroprotection.
Trends in molecular medicine Jan, 2020 | Pubmed ID: 31375365
The Cytoskeleton as a Modulator of Aging and Neurodegeneration.
Advances in experimental medicine and biology , 2019 | Pubmed ID: 31493230
Synaptic vesicle fusion is modulated through feedback inhibition by dopamine auto-receptors.
Synapse (New York, N.Y.) 01, 2020 | Pubmed ID: 31494966
SUMOylation in Neurodegenerative Diseases.
Gerontology , 2020 | Pubmed ID: 31505513
Emerging Roles of Lipophagy in Health and Disease.
Frontiers in cell and developmental biology , 2019 | Pubmed ID: 31552248
3,4-Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB.
EMBO molecular medicine 11, 2019 | Pubmed ID: 31609086
Sex-specific regulation of neuronal functions in Caenorhabditis elegans: the sex-determining protein TRA-1 represses goa-1/Gα.
Molecular genetics and genomics : MGG Mar, 2020 | Pubmed ID: 31776761
Acyl-CoA-binding protein (ACBP): a phylogenetically conserved appetite stimulator.
Cell death & disease 01, 2020 | Pubmed ID: 31907349
Caenorhabditis elegans as a model system for human diseases.
Current opinion in biotechnology Jun, 2020 | Pubmed ID: 31951916
ACBP is an appetite stimulator across phylogenetic barriers.
Cell stress Jan, 2020 | Pubmed ID: 32043075
Regulation and roles of mitophagy at synapses.
Mechanisms of ageing and development 04, 2020 | Pubmed ID: 32084458
Crosstalk between Endo/Exocytosis and Autophagy in Health and Disease.
Biotechnology journal Aug, 2020 | Pubmed ID: 32143239
Mitochondrial turnover and homeostasis in ageing and neurodegeneration.
FEBS letters Apr, 2020 | Pubmed ID: 32350855
Molecular Interventions towards Multiple Sclerosis Treatment.
Brain sciences May, 2020 | Pubmed ID: 32429225
Regulation and Roles of Autophagy in the Brain.
Advances in experimental medicine and biology , 2020 | Pubmed ID: 32468455
Editorial: Mitophagy in physiology and pathology.
Mechanisms of ageing and development Jun, 2020 | Pubmed ID: 32569605
Nucleophagy mediators and mechanisms.
Progress in molecular biology and translational science , 2020 | Pubmed ID: 32620238
Inhibition of autophagy curtails visual loss in a model of autosomal dominant optic atrophy.
Nature communications Aug, 2020 | Pubmed ID: 32788597
Inflammation brakes mitochondrial metabolism in obesity.
Nature immunology Aug, 2020 | Pubmed ID: 32855554
Mitochondrial biogenesis in organismal senescence and neurodegeneration.
Mechanisms of ageing and development Sep, 2020 | Pubmed ID: 32891602
Evandro F. Fang1,6,
Konstantinos Palikaras2,
Nuo Sun3,
Elayne M. Fivenson1,
Ryan D. Spangler4,
Jesse S. Kerr1,
Stephanie A. Cordonnier1,
Yujun Hou1,
Eszter Dombi5,
Henok Kassahun6,
Nektarios Tavernarakis2,7,
Joanna Poulton5,
Hilde Nilsen6,
Vilhelm A. Bohr1,8
1Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health,
2Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas,
3Center for Molecular Medicine, National Heart Lung and Blood Institute, National Institutes of Health,
4Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health,
5Nuffield Department of Obstetrics and Gynaecology, University of Oxford,
6Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital,
7Department of Basic Sciences, Faculty of Medicine, University of Crete,
8Danish Center for Healthy Aging, University of Copenhagen
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