Yana Zavros

The adventures of sonic hedgehog in development and repair. IV. Sonic hedgehog processing, secretion, and function in the stomach.

Sonic hedgehog is associated with H+-K+-ATPase-containing membranes in gastric parietal cells and secreted with histamine stimulation.

Loss of parietal cell expression of Sonic hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells.

The full-length unprocessed hedgehog protein is an active signaling molecule.

Volume density, distribution, and ultrastructure of secretory and basolateral membranes and mitochondria predict parietal cell secretory (dys)function.

The role of sonic hedgehog reemergence during gastric cancer.

Intracellular calcium release and protein kinase C activation stimulate sonic hedgehog gene expression during gastric acid secretion.

Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions.

Histamine 3 receptor activation mediates inhibition of acid secretion during Helicobacter-induced gastritis.

Role of Sonic Hedgehog signaling during progression from inflammation to cancer in the stomach.

Gastric Sonic Hedgehog Acts as a Macrophage Chemoattractant During the Immune Response to Helicobacter pylori.

The role of Sonic Hedgehog as a regulator of gastric function and differentiation.

Variants in autophagy genes affect susceptibility to both Crohn's disease and Helicobacter pylori infection.

Techniques for following labeled cells in vivo: use of X/Y FISH, techniques to optimize fluorescent detection, and beta-galactosidase detection.

Sonic Hedgehog contributes to gastric mucosal restitution after injury.

Sonic hedgehog mediates the proliferation and recruitment of transformed mesenchymal stem cells to the stomach.

The acid-secreting parietal cell as an endocrine source of Sonic Hedgehog during gastric repair.

Gastritis promotes an activated bone marrow-derived mesenchymal stem cell with a phenotype reminiscent of a cancer-promoting cell.

Mesenchymal stem cells induce epithelial proliferation within the inflamed stomach.

Indian Hedgehog mediates gastrin-induced proliferation in stomach of adult mice.

Motility and chemotaxis mediate the preferential colonization of gastric injury sites by Helicobacter pylori.

Establishment of gastrointestinal epithelial organoids.

Helicobacter pylori targets cancer-associated apical-junctional constituents in gastroids and gastric epithelial cells.

Modelling human development and disease in pluripotent stem-cell-derived gastric organoids.

Crosstalks between cytokines and Sonic Hedgehog in Helicobacter pylori infection: a mathematical model.

Helicobacter pylori-induced Sonic Hedgehog expression is regulated by NFκB pathway activation: the use of a novel in vitro model to study epithelial response to infection.

The use of murine-derived fundic organoids in studies of gastric physiology.

CD44 Plays a Functional Role in Helicobacter pylori-induced Epithelial Cell Proliferation.

Characterization of stem/progenitor cell cycle using murine circumvallate papilla taste bud organoid.

Organoid Models of Human Gastrointestinal Development and Disease.

Co-culture of Gastric Organoids and Immortalized Stomach Mesenchymal Cells.

Oncogenic Transformation of Human-Derived Gastric Organoids.

Spatial and Temporal Shifts in Bacterial Biogeography and Gland Occupation during the Development of a Chronic Infection.

Hedgehog signaling in the stomach.

The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged Stomach.

Hedgehog signalling in myeloid cells impacts on body weight, adipose tissue inflammation and glucose metabolism.

CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium.

Initiation and Maintenance of Gastric Cancer: A Focus on CD44 Variant Isoforms and Cancer Stem Cells.

The Novel Role of as a Regulator of Cell Homeostasis and Disease of the Gastric Oxyntic Mucosa.

Generation and use of gastric organoids for the study of Helicobacter pylori pathogenesis.

Human Gastrointestinal Organoid Models for Studying Microbial Disease and Cancer.