Andrew Wolfe

Temporal and spatial regulation of CRE recombinase expression in gonadotrophin-releasing hormone neurones in the mouse.

Development of an immortalised, post-pubertal gonadotrophin-releasing hormone neuronal cell line.

Generation and characterization of a complete null estrogen receptor alpha mouse using Cre/LoxP technology.

Estrogen regulation of gene expression in GnRH neurons.

Impaired estrogen feedback and infertility in female mice with pituitary-specific deletion of estrogen receptor alpha (ESR1).

Kisspeptin increases GnRH mRNA expression and secretion in GnRH secreting neuronal cell lines.

Rescue of obesity-induced infertility in female mice due to a pituitary-specific knockout of the insulin receptor.

Jak2 is necessary for neuroendocrine control of female reproduction.

The gonadotropin-releasing hormone cell-specific element is required for normal puberty and estrous cyclicity.

Deletion of Otx2 in GnRH neurons results in a mouse model of hypogonadotropic hypogonadism.

Loss of epithelial oestrogen receptor α inhibits oestrogen-stimulated prostate proliferation and squamous metaplasia via in vivo tissue selective knockout models.

Reproductive tissues maintain insulin sensitivity in diet-induced obesity.

Signaling of cytokines is important in regulation of GnRH neurons.

Estrogen receptor-β in the gonadotropin-releasing hormone neuron.

CREB binding protein (CBP) activation is required for luteinizing hormone beta expression and normal fertility in mice.

Estrogenic regulation of the GnRH neuron.

A low-copy-number plasmid for retrieval of toxic genes from BACs and generation of conditional targeting constructs.

Gene therapy to prolong reproductive life.

Obesity-induced infertility and hyperandrogenism are corrected by deletion of the insulin receptor in the ovarian theca cell.

Disrupted kisspeptin signaling in GnRH neurons leads to hypogonadotrophic hypogonadism.

Glucagon regulates hepatic kisspeptin to impair insulin secretion.

Hypothalamic molecular changes underlying natural reproductive senescence in the female rat.

The regulation of reproductive neuroendocrine function by insulin and insulin-like growth factor-1 (IGF-1).

Dynamic and extensive metabolic state-dependent regulation of cytokine expression and circulating levels.

Positive, but not negative feedback actions of estradiol in adult female mice require estrogen receptor α in kisspeptin neurons.

Developmental and endocrine regulation of kisspeptin expression in mouse Leydig cells.

Substance p regulates puberty onset and fertility in the female mouse.

Testing the Critical Window Hypothesis of Timing and Duration of Estradiol Treatment on Hypothalamic Gene Networks in Reproductively Mature and Aging Female Rats.

Maternal Vitamin D Deficiency Programs Reproductive Dysfunction in Female Mice Offspring Through Adverse Effects on the Neuroendocrine Axis.

Estradiol Restrains Prepubertal Gonadotropin Secretion in Female Mice via Activation of ERα in Kisspeptin Neurons.

The Methylcytosine Dioxygenase Ten-Eleven Translocase-2 (tet2) Enables Elevated GnRH Gene Expression and Maintenance of Male Reproductive Function.

Loss of Fertility in the Absence of Progesterone Receptor Expression in Kisspeptin Neurons of Female Mice.

Adverse Reproductive and Developmental Health Outcomes Following Prenatal Exposure to a Hydraulic Fracturing Chemical Mixture in Female C57Bl/6 Mice.

Low-Dose Dihydrotestosterone Drives Metabolic Dysfunction via Cytosolic and Nuclear Hepatic Androgen Receptor Mechanisms.

Aging and estradiol effects on gene expression in the medial preoptic area, bed nucleus of the stria terminalis, and posterodorsal medial amygdala of male rats.

Hepatic estrogen receptor α is critical for regulation of gluconeogenesis and lipid metabolism in males.

Multiplex Quantification Identifies Novel Exercise-regulated Myokines/Cytokines in Plasma and in Glycolytic and Oxidative Skeletal Muscle.