Laboratory of Cell Biology,
Center for Cancer Research,
National Cancer Institute,
Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute
Sriram Subramaniam has not added Biography.
If you are Sriram Subramaniam and would like to personalize this page please email our Author Liaison for assistance.
Compositional mapping of the surface and interior of mammalian cells at submicrometer resolution.
Analytical chemistry Feb, 2011 | Pubmed ID: 21268648
Role of HDAC3 on p53 expression and apoptosis in T cells of patients with multiple sclerosis.
PloS one , 2011 | Pubmed ID: 21346816
Increased severity of experimental allergic encephalomyelitis in lyn-/- mice in the absence of elevated proinflammatory cytokine response in the central nervous system.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2002 | Pubmed ID: 11884485
Three-dimensional structure of a bacterial oxalate transporter.
Nature structural biology Aug, 2002 | Pubmed ID: 12118242
Molecular architecture and mechanism of an icosahedral pyruvate dehydrogenase complex: a multifunctional catalytic machine.
The EMBO journal Nov, 2002 | Pubmed ID: 12411477
Comparative study of the presence of Chlamydia pneumoniae in cerebrospinal fluid of Patients with clinically definite and monosymptomatic multiple sclerosis.
Clinical and diagnostic laboratory immunology Nov, 2002 | Pubmed ID: 12414770
Chlamydia pneumoniae infection of the central nervous system worsens experimental allergic encephalitis.
The Journal of experimental medicine Dec, 2002 | Pubmed ID: 12486106
A core-weighted fitting method for docking atomic structures into low-resolution maps: application to cryo-electron microscopy.
Journal of structural biology Jan, 2003 | Pubmed ID: 12576021
Structural model for 12-helix transporters belonging to the major facilitator superfamily.
Journal of bacteriology Mar, 2003 | Pubmed ID: 12591890
Electron microscopic analysis of membrane assemblies formed by the bacterial chemotaxis receptor Tsr.
Journal of bacteriology Jun, 2003 | Pubmed ID: 12775701
Structural insights into the mechanism of proton pumping by bacteriorhodopsin.
FEBS letters Jun, 2003 | Pubmed ID: 12788485
From structure to mechanism: electron crystallographic studies of bacteriorhodopsin.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences May, 2002 | Pubmed ID: 12804283
Automated image acquisition and processing using a new generation of 4K x 4K CCD cameras for cryo electron microscopic studies of macromolecular assemblies.
Journal of structural biology Aug, 2003 | Pubmed ID: 12972350
CNS infection with C. pneumoniae complicated by multiple strokes.
Journal of neurology Sep, 2003 | Pubmed ID: 14504982
Association of Chlamydia pneumoniae with central nervous system disease.
Microbes and infection / Institut Pasteur Nov, 2003 | Pubmed ID: 14623021
Projection structure of the bacterial oxalate transporter OxlT at 3.4A resolution.
Journal of structural biology Dec, 2003 | Pubmed ID: 14643200
Signaling through JAK2-STAT5 pathway is essential for IL-3-induced activation of microglia.
Glia Jan, 2004 | Pubmed ID: 14730712
Three-dimensional electron microscopy at molecular resolution.
Annual review of biophysics and biomolecular structure , 2004 | Pubmed ID: 15139808
Three-dimensional electron microscopic imaging of membrane invaginations in Escherichia coli overproducing the chemotaxis receptor Tsr.
Journal of bacteriology Aug, 2004 | Pubmed ID: 15262942
Structure and transport mechanism of the bacterial oxalate transporter OxlT.
Biophysical journal Nov, 2004 | Pubmed ID: 15339805
Role of microglia in multiple sclerosis.
Current neurology and neuroscience reports May, 2005 | Pubmed ID: 15865890
Electron tomography of degenerating neurons in mice with abnormal regulation of iron metabolism.
Journal of structural biology May, 2005 | Pubmed ID: 15866737
Bridging the imaging gap: visualizing subcellular architecture with electron tomography.
Current opinion in microbiology Jun, 2005 | Pubmed ID: 15939356
Detection of chlamydial bodies and antigens in the central nervous system of patients with multiple sclerosis.
The Journal of infectious diseases Oct, 2005 | Pubmed ID: 16136465
Defective ATM-p53-mediated apoptotic pathway in multiple sclerosis.
Annals of neurology Oct, 2005 | Pubmed ID: 16178012
An energy-based three-dimensional segmentation approach for the quantitative interpretation of electron tomograms.
IEEE transactions on image processing : a publication of the IEEE Signal Processing Society Sep, 2005 | Pubmed ID: 16190467
Molecular structure of a 9-MDa icosahedral pyruvate dehydrogenase subcomplex containing the E2 and E3 enzymes using cryoelectron microscopy.
The Journal of biological chemistry Feb, 2006 | Pubmed ID: 16308322
Experimental allergic encephalomyelitis: a misleading model of multiple sclerosis.
Annals of neurology Dec, 2005 | Pubmed ID: 16315280
Site-specific 3D imaging of cells and tissues with a dual beam microscope.
Journal of structural biology Jul, 2006 | Pubmed ID: 16713294
The SIV surface spike imaged by electron tomography: one leg or three?
PLoS pathogens Aug, 2006 | Pubmed ID: 16933994
Infectious causes of multiple sclerosis.
Lancet neurology Oct, 2006 | Pubmed ID: 16987736
Automated 100-position specimen loader and image acquisition system for transmission electron microscopy.
Journal of structural biology Jun, 2007 | Pubmed ID: 17240161
Gray matter involvement in multiple sclerosis.
Neurology Feb, 2007 | Pubmed ID: 17325269
Electron tomography of bacterial chemotaxis receptor assemblies.
Methods in cell biology , 2007 | Pubmed ID: 17327165
Direct visualization of Escherichia coli chemotaxis receptor arrays using cryo-electron microscopy.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2007 | Pubmed ID: 17360429
Identification of molecular biomarkers for multiple sclerosis.
The Journal of molecular diagnostics : JMD Apr, 2007 | Pubmed ID: 17384211
Electron tomography of the contact between T cells and SIV/HIV-1: implications for viral entry.
PLoS pathogens May, 2007 | Pubmed ID: 17480119
In regard to Miller et al.: Multiple sclerosis, brain radiotherapy and risk of neurotoxicity: the Mayo Clinic experience (Int J Radiat Oncol Biol Phys 2006;66:1178-1186).
International journal of radiation oncology, biology, physics Jul, 2007 | Pubmed ID: 17544007
Cryoelectron tomographic analysis of an HIV-neutralizing protein and its complex with native viral gp120.
The Journal of biological chemistry Sep, 2007 | Pubmed ID: 17599917
Cell surface filaments of the gliding bacterium Flavobacterium johnsoniae revealed by cryo-electron tomography.
Journal of bacteriology Oct, 2007 | Pubmed ID: 17693495
Electron tomography of viruses.
Current opinion in structural biology Oct, 2007 | Pubmed ID: 17964134
Stoichiometry and absolute quantification of proteins with mass spectrometry using fluorescent and isotope-labeled concatenated peptide standards.
Molecular & cellular proteomics : MCP Feb, 2008 | Pubmed ID: 18029347
Extended polypeptide linkers establish the spatial architecture of a pyruvate dehydrogenase multienzyme complex.
Structure (London, England : 1993) Jan, 2008 | Pubmed ID: 18184587
Three-dimensional imaging of the highly bent architecture of Bdellovibrio bacteriovorus by using cryo-electron tomography.
Journal of bacteriology Apr, 2008 | Pubmed ID: 18203829
TRAPS and MS: two diseases or an MS mimic?
Neurology Mar, 2008 | Pubmed ID: 18362272
Electron tomography in nanoparticle imaging and analysis.
Nanomedicine (London, England) Feb, 2008 | Pubmed ID: 18393671
Preconditioning with cobalt chloride or desferrioxamine protects oligodendrocyte cell line (MO3.13) from tumor necrosis factor-alpha-mediated cell death.
Journal of neuroscience research Aug, 2008 | Pubmed ID: 18438939
Evaluation of denoising algorithms for biological electron tomography.
Journal of structural biology Oct, 2008 | Pubmed ID: 18585059
Tolerability and safety profile of 12- to 28-week treatment with interferon beta-1b 250 and 500 microg QOD in patients with relapsing-remitting multiple sclerosis: a multicenter, randomized, double-blind, parallel-group pilot study.
Clinical therapeutics Jun, 2008 | Pubmed ID: 18640466
Molecular architecture of native HIV-1 gp120 trimers.
Nature Sep, 2008 | Pubmed ID: 18668044
Chemoreceptors in Caulobacter crescentus: trimers of receptor dimers in a partially ordered hexagonally packed array.
Journal of bacteriology Oct, 2008 | Pubmed ID: 18689468
Bacterial cell wall products increases stabilization of HIF-1 alpha in an oligodendrocyte cell line preconditioned by cobalt chloride or desferrioxamine.
Journal of neuroimmunology Aug, 2008 | Pubmed ID: 18715655
Aphasic or amnesic status epilepticus detected on PET but not EEG.
Epilepsia Feb, 2009 | Pubmed ID: 18801038
Role of HAMP domains in chemotaxis signaling by bacterial chemoreceptors.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2008 | Pubmed ID: 18940922
3D imaging of mammalian cells with ion-abrasion scanning electron microscopy.
Journal of structural biology Apr, 2009 | Pubmed ID: 19116171
The spectrum of Susac's syndrome.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology Feb, 2009 | Pubmed ID: 19145401
3D imaging of diatoms with ion-abrasion scanning electron microscopy.
Journal of structural biology Jun, 2009 | Pubmed ID: 19269330
Qualitative and quantitative detection of Chlamydophila pneumoniae DNA in cerebrospinal fluid from multiple sclerosis patients and controls.
PloS one , 2009 | Pubmed ID: 19357786
Protein conformational changes in the bacteriorhodopsin photocycle: comparison of findings from electron and X-ray crystallographic analyses.
PloS one , 2009 | Pubmed ID: 19488399
Staphylococcal enterotoxin A induces small clusters of HLA-DR1 on B cells.
PloS one , 2009 | Pubmed ID: 19587800
Structural snapshots of conformational changes in a seven-helix membrane protein: lessons from bacteriorhodopsin.
Current opinion in structural biology Aug, 2009 | Pubmed ID: 19643594
Membrane protein structure determination using cryo-electron tomography and 3D image averaging.
Current opinion in structural biology Aug, 2009 | Pubmed ID: 19646859
Cryo-electron tomography of bacteria: progress, challenges and future prospects.
Nature reviews. Microbiology Sep, 2009 | Pubmed ID: 19668224
Identification and characterization of the interferon-beta-mediated p53 signal pathway in human peripheral blood mononuclear cells.
Immunology Sep, 2009 | Pubmed ID: 19740351
Ion-abrasion scanning electron microscopy reveals surface-connected tubular conduits in HIV-infected macrophages.
PLoS pathogens Sep, 2009 | Pubmed ID: 19779568
Ion-abrasion scanning electron microscopy reveals distorted liver mitochondrial morphology in murine methylmalonic acidemia.
Journal of structural biology Aug, 2010 | Pubmed ID: 20399866
3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2010 | Pubmed ID: 20624966
The role of infections in the pathogenesis and course of multiple sclerosis.
Annals of Indian Academy of Neurology Apr, 2010 | Pubmed ID: 20814489
A coiled-coil-repeat protein 'Ccrp' in Bdellovibrio bacteriovorus prevents cellular indentation, but is not essential for vibroid cell morphology.
FEMS microbiology letters Dec, 2010 | Pubmed ID: 20977494
Spiral architecture of the nucleoid in Bdellovibrio bacteriovorus.
Journal of bacteriology Mar, 2011 | Pubmed ID: 21148724
Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure.
PLoS pathogens , 2010 | Pubmed ID: 21203482
Chemotaxis kinase CheA is activated by three neighbouring chemoreceptor dimers as effectively as by receptor clusters.
Molecular microbiology Feb, 2011 | Pubmed ID: 21255111
Development of chemical exchange saturation transfer at 7 T.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Sep, 2011 | Pubmed ID: 21432902
Lateral density of receptor arrays in the membrane plane influences sensitivity of the E. coli chemotaxis response.
The EMBO journal May, 2011 | Pubmed ID: 21441899
HIV-1 activates Cdc42 and induces membrane extensions in immature dendritic cells to facilitate cell-to-cell virus propagation.
Blood Nov, 2011 | Pubmed ID: 21562048
Structural plasticity of a transmembrane peptide allows self-assembly into biologically active nanoparticles.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2011 | Pubmed ID: 21628584
Analysis of T2 Intensity by Magnetic Resonance Imaging of Deep Gray Matter Nuclei in Multiple Sclerosis Patients: Effect of Immunomodulatory Therapies.
Journal of neuroimaging : official journal of the American Society of Neuroimaging Jun, 2011 | Pubmed ID: 21707826
Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2011 | Pubmed ID: 21709254
Role of glial cells in innate immunity and their role in CNS demyelination.
Journal of neuroimmunology Oct, 2011 | Pubmed ID: 21907419
Correlative 3D imaging of whole mammalian cells with light and electron microscopy.
Journal of structural biology Dec, 2011 | Pubmed ID: 21907806
Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography.
Journal of virology Dec, 2011 | Pubmed ID: 21937655
Chemical mapping of mammalian cells by atom probe tomography.
Journal of structural biology Jan, 2012 | Pubmed ID: 22245777
Computational separation of conformational heterogeneity using cryo-electron tomography and 3D sub-volume averaging.
Journal of structural biology Jan, 2012 | Pubmed ID: 22248450
Joel R. Meyerson1,2,
Tommi A. White1,
Donald Bliss3,
Amy Moran3,
Alberto Bartesaghi1,
Mario J. Borgnia1,
M. Jason V. de la Cruz1,
David Schauder1,
Lisa M. Hartnell1,
Rachna Nandwani1,4,
Moez Dawood5,
Brianna Kim6,
Jun Hong Kim7,
John Sununu8,
Lisa Yang9,
Siddhant Bhatia10,
Carolyn Subramaniam1,
Darrell E. Hurt11,
Laurent Gaudreault12,
Sriram Subramaniam1
1Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health,
2The Medical Research Council Mitochondrial Biology Unit, University of Cambridge ,
3National Library of Medicine, National Institutes of Health,
4, Massachusetts Institute of Technology,
5, William Fremd High School,
6, University of Virginia ,
7, Duke University ,
8, Yale University,
9, University of Notre Dame ,
10, Washington University in St. Louis ,
11Bioinformatics and Computational Biosciences Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health,
12, Thomas Jefferson High School for Science and Technology
JoVE Hakkında
Telif Hakkı © 2020 MyJove Corporation. Tüm hakları saklıdır