Sriram Subramaniam

Compositional mapping of the surface and interior of mammalian cells at submicrometer resolution.

Role of HDAC3 on p53 expression and apoptosis in T cells of patients with multiple sclerosis.

Increased severity of experimental allergic encephalomyelitis in lyn-/- mice in the absence of elevated proinflammatory cytokine response in the central nervous system.

Three-dimensional structure of a bacterial oxalate transporter.

Molecular architecture and mechanism of an icosahedral pyruvate dehydrogenase complex: a multifunctional catalytic machine.

Comparative study of the presence of Chlamydia pneumoniae in cerebrospinal fluid of Patients with clinically definite and monosymptomatic multiple sclerosis.

Chlamydia pneumoniae infection of the central nervous system worsens experimental allergic encephalitis.

A core-weighted fitting method for docking atomic structures into low-resolution maps: application to cryo-electron microscopy.

Structural model for 12-helix transporters belonging to the major facilitator superfamily.

Electron microscopic analysis of membrane assemblies formed by the bacterial chemotaxis receptor Tsr.

Structural insights into the mechanism of proton pumping by bacteriorhodopsin.

From structure to mechanism: electron crystallographic studies of bacteriorhodopsin.

Automated image acquisition and processing using a new generation of 4K x 4K CCD cameras for cryo electron microscopic studies of macromolecular assemblies.

CNS infection with C. pneumoniae complicated by multiple strokes.

Association of Chlamydia pneumoniae with central nervous system disease.

Projection structure of the bacterial oxalate transporter OxlT at 3.4A resolution.

Signaling through JAK2-STAT5 pathway is essential for IL-3-induced activation of microglia.

Three-dimensional electron microscopy at molecular resolution.

Three-dimensional electron microscopic imaging of membrane invaginations in Escherichia coli overproducing the chemotaxis receptor Tsr.

Structure and transport mechanism of the bacterial oxalate transporter OxlT.

Role of microglia in multiple sclerosis.

Electron tomography of degenerating neurons in mice with abnormal regulation of iron metabolism.

Bridging the imaging gap: visualizing subcellular architecture with electron tomography.

Detection of chlamydial bodies and antigens in the central nervous system of patients with multiple sclerosis.

Defective ATM-p53-mediated apoptotic pathway in multiple sclerosis.

An energy-based three-dimensional segmentation approach for the quantitative interpretation of electron tomograms.

Molecular structure of a 9-MDa icosahedral pyruvate dehydrogenase subcomplex containing the E2 and E3 enzymes using cryoelectron microscopy.

Experimental allergic encephalomyelitis: a misleading model of multiple sclerosis.

Site-specific 3D imaging of cells and tissues with a dual beam microscope.

The SIV surface spike imaged by electron tomography: one leg or three?

Infectious causes of multiple sclerosis.

Automated 100-position specimen loader and image acquisition system for transmission electron microscopy.

Gray matter involvement in multiple sclerosis.

Electron tomography of bacterial chemotaxis receptor assemblies.

Direct visualization of Escherichia coli chemotaxis receptor arrays using cryo-electron microscopy.

Identification of molecular biomarkers for multiple sclerosis.

Electron tomography of the contact between T cells and SIV/HIV-1: implications for viral entry.

In regard to Miller et al.: Multiple sclerosis, brain radiotherapy and risk of neurotoxicity: the Mayo Clinic experience (Int J Radiat Oncol Biol Phys 2006;66:1178-1186).

Cryoelectron tomographic analysis of an HIV-neutralizing protein and its complex with native viral gp120.

Cell surface filaments of the gliding bacterium Flavobacterium johnsoniae revealed by cryo-electron tomography.

Electron tomography of viruses.

Stoichiometry and absolute quantification of proteins with mass spectrometry using fluorescent and isotope-labeled concatenated peptide standards.

Extended polypeptide linkers establish the spatial architecture of a pyruvate dehydrogenase multienzyme complex.

Three-dimensional imaging of the highly bent architecture of Bdellovibrio bacteriovorus by using cryo-electron tomography.

TRAPS and MS: two diseases or an MS mimic?

Electron tomography in nanoparticle imaging and analysis.

Preconditioning with cobalt chloride or desferrioxamine protects oligodendrocyte cell line (MO3.13) from tumor necrosis factor-alpha-mediated cell death.

Evaluation of denoising algorithms for biological electron tomography.

Tolerability and safety profile of 12- to 28-week treatment with interferon beta-1b 250 and 500 microg QOD in patients with relapsing-remitting multiple sclerosis: a multicenter, randomized, double-blind, parallel-group pilot study.

Molecular architecture of native HIV-1 gp120 trimers.

Chemoreceptors in Caulobacter crescentus: trimers of receptor dimers in a partially ordered hexagonally packed array.

Bacterial cell wall products increases stabilization of HIF-1 alpha in an oligodendrocyte cell line preconditioned by cobalt chloride or desferrioxamine.

Aphasic or amnesic status epilepticus detected on PET but not EEG.

Role of HAMP domains in chemotaxis signaling by bacterial chemoreceptors.

3D imaging of mammalian cells with ion-abrasion scanning electron microscopy.

The spectrum of Susac's syndrome.

3D imaging of diatoms with ion-abrasion scanning electron microscopy.

Qualitative and quantitative detection of Chlamydophila pneumoniae DNA in cerebrospinal fluid from multiple sclerosis patients and controls.

Protein conformational changes in the bacteriorhodopsin photocycle: comparison of findings from electron and X-ray crystallographic analyses.

Staphylococcal enterotoxin A induces small clusters of HLA-DR1 on B cells.

Structural snapshots of conformational changes in a seven-helix membrane protein: lessons from bacteriorhodopsin.

Membrane protein structure determination using cryo-electron tomography and 3D image averaging.

Cryo-electron tomography of bacteria: progress, challenges and future prospects.

Identification and characterization of the interferon-beta-mediated p53 signal pathway in human peripheral blood mononuclear cells.

Ion-abrasion scanning electron microscopy reveals surface-connected tubular conduits in HIV-infected macrophages.

Ion-abrasion scanning electron microscopy reveals distorted liver mitochondrial morphology in murine methylmalonic acidemia.

3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells.

The role of infections in the pathogenesis and course of multiple sclerosis.

A coiled-coil-repeat protein 'Ccrp' in Bdellovibrio bacteriovorus prevents cellular indentation, but is not essential for vibroid cell morphology.

Spiral architecture of the nucleoid in Bdellovibrio bacteriovorus.

Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure.

Chemotaxis kinase CheA is activated by three neighbouring chemoreceptor dimers as effectively as by receptor clusters.

Development of chemical exchange saturation transfer at 7 T.

Lateral density of receptor arrays in the membrane plane influences sensitivity of the E. coli chemotaxis response.

HIV-1 activates Cdc42 and induces membrane extensions in immature dendritic cells to facilitate cell-to-cell virus propagation.

Structural plasticity of a transmembrane peptide allows self-assembly into biologically active nanoparticles.

Analysis of T2 Intensity by Magnetic Resonance Imaging of Deep Gray Matter Nuclei in Multiple Sclerosis Patients: Effect of Immunomodulatory Therapies.

Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures.

Role of glial cells in innate immunity and their role in CNS demyelination.

Correlative 3D imaging of whole mammalian cells with light and electron microscopy.

Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography.

Chemical mapping of mammalian cells by atom probe tomography.

Computational separation of conformational heterogeneity using cryo-electron tomography and 3D sub-volume averaging.