Frederick A. Villamena

Theoretical study of the spin trapping of hydroxyl radical by cyclic nitrones: a density functional theory approach.

Detection of reactive oxygen and nitrogen species by EPR spin trapping.

Spin trapping by 5-carbamoyl-5-methyl-1-pyrroline N-oxide (AMPO): theoretical and experimental studies.

Cancer chemopreventive oltipraz generates superoxide anion radical.

Glutathione-mediated formation of oxygen free radicals by the major metabolite of oltipraz.

Nitric oxide release from the unimolecular decomposition of the superoxide radical anion adduct of cyclic nitrones in aqueous medium.

Comparative DFT study of the spin trapping of methyl, mercapto, hydroperoxy, superoxide, and nitric oxide radicals by various substituted cyclic nitrones.

Superoxide radical anion adduct of 5,5-dimethyl-1-pyrroline n-oxide (DMPO). 1. The thermodynamics of formation and its acidity.

Superoxide radical anion adduct of 5,5-dimethyl-1-pyrroline N-oxide (DMPO). 2. The thermodynamics of decay and EPR spectral properties.

Evidence for increased exchange interactions with 5d compared to 4d metal ions. Experimental and theoretical insights into the ferromagnetic interactions of a series of trinuclear [{M(CN)8}3-/NiII] compounds (M = MoV or WV).

Reactivity of molecular oxygen with ethoxycarbonyl derivatives of tetrathiatriarylmethyl radicals.

Theoretical and experimental studies of the spin trapping of inorganic radicals by 5,5-dimethyl-1-pyrroline N-oxide (DMPO). 1. Carbon dioxide radical anion.

Theoretical and experimental studies of the spin trapping of inorganic radicals by 5,5-dimethyl-1-pyrroline N-oxide (DMPO). 2. Carbonate radical anion.

4-Aryl-1,3,2-oxathiazolylium-5-olates as pH-controlled NO-donors: the next generation of S-nitrosothiols.

Synthesis and characterization of a perchlorotriphenylmethyl (trityl) triester radical: a potential sensor for superoxide and oxygen in biological systems.

Reactivity of superoxide radical anion with cyclic nitrones: role of intramolecular H-bond and electrostatic effects.

Rate constants of hydroperoxyl radical addition to cyclic nitrones: a DFT study.

Large-scale synthesis of a persistent trityl radical for use in biomedical EPR applications and imaging.

Reactivity of superoxide anion radical with a perchlorotriphenylmethyl (trityl) radical.

Inactivation of mitochondrial respiratory chain complex I leads mitochondrial nitric oxide synthase to become pro-oxidative.

Synthesis and characterization of ester-derivatized tetrathiatriarylmethyl radicals as intracellular oxygen probes.

Superoxide radical anion adduct of 5,5-dimethyl-1-pyrroline N-oxide (DMPO). 3. Effect of mildly acidic pH on the thermodynamics and kinetics of adduct formation.

Synthesis and spin-trapping properties of a new spirolactonyl nitrone.

Improved spin trapping properties by beta-cyclodextrin-cyclic nitrone conjugate.

Highly stable dendritic trityl radicals as oxygen and pH probe.

Theoretical and experimental studies of tyrosyl hydroperoxide formation in the presence of H-bond donors.

Reactivity of superoxide radical anion and hydroperoxyl radical with alpha-phenyl-N-tert-butylnitrone (PBN) derivatives.

Superoxide radical anion adduct of 5,5-dimethyl-1-pyrroline N-oxide. 4. Conformational effects on the EPR hyperfine splitting constants.

Esterified trityl radicals as intracellular oxygen probes.

The radical trap 5,5-dimethyl-1-pyrroline N-oxide exerts dose-dependent protection against myocardial ischemia-reperfusion injury through preservation of mitochondrial electron transport.

Superoxide radical anion adduct of 5,5-dimethyl-1-pyrroline N-oxide. 5. Thermodynamics and kinetics of unimolecular decomposition.

Lipophilic beta-cyclodextrin cyclic-nitrone conjugate: synthesis and spin trapping studies.

Spin trapping and cytoprotective properties of fluorinated amphiphilic carrier conjugates of cyclic versus linear nitrones.

Perchlorotrityl radical-fluorophore conjugates as dual fluorescence and EPR probes for superoxide radical anion.

Superoxide radical anion adduct of 5,5-dimethyl-1-pyrroline N-oxide. 6. Redox properties.

Trityl-nitroxide biradicals as unique molecular probes for the simultaneous measurement of redox status and oxygenation.

Amphiphilic amide nitrones: a new class of protective agents acting as modifiers of mitochondrial metabolism.

Synthesis of (14)N- and (15)N-labeled Trityl-nitroxide Biradicals with Strong Spin-Spin Interaction and Improved Sensitivity to Redox Status and Oxygen.

Fast Reactivity of a Cyclic Nitrone-Calix[4]pyrrole Conjugate with Superoxide Radical Anion: Theoretical and Experimental Studies (†).

Synthesis of trityl radical-conjugated disulfide biradicals for measurement of thiol concentration.

Physicochemical and toxicological properties of commercial carbon blacks modified by reaction with ozone.

Reactivities of superoxide and hydroperoxyl radicals with disubstituted cyclic nitrones: a DFT study.

Synthesis of tris-hydroxymethyl-based nitrone derivatives with highly reactive nitronyl carbon.

Inhibition of ROS-induced apoptosis in endothelial cells by nitrone spin traps via induction of phase II enzymes and suppression of mitochondria-dependent pro-apoptotic signaling.

Theoretical and Experimental Studies of the Spin Trapping of Inorganic Radicals by 5,5-Dimethyl-1-pyrroline N-Oxide (DMPO). 3. Sulfur Dioxide, Sulfite, and Sulfate Radical Anions.

Potential implication of the chemical properties and bioactivity of nitrone spin traps for therapeutics.

Reactive Nitrogen Species Reactivities with Nitrones: Theoretical and Experimental Studies.

Guest Inclusion in Cucurbiturils Studied by ESR and DFT: The Case of Nitroxide Radicals and Spin Adducts of DMPO and MNP.