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Katharina Schmidt-Bleek

Berlin-Brandenburg Center for Regenerative Therapies (BCRT),
Charité - Universitätsmedizin Berlin,
corporate member of Freie Universität Berlin,
Julius Wolff Institute (JWI) and Center for Musculoskeletal Surgery,
Berlin,
Germany,
Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin,
Julius Wolff Institute (JWI) and Center for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany, corporate member of Freie Universität Berlin

Humboldt-Universität zu Berlin

BIOGRAPHY

Professional Development

• Since 2012 Research Group Leader “Biology of Bone Healing”

• Since 2010 Prinzipal Investigator “Osteoimmunology”

• Since 2006 Veterinarian and Postdoctoral Research Fellow at the Julius Wolff Institute, Charité – Universitätsmedizin Berlin

• April 2006 Approbation

• 1999 – 2006 Study of Veterinary Medicine, Freie Universität Berlin

• Juni 1997 Dissertation, Freie Universität Berlin

• 1994 – 1997 Doctoral Thesis in Molecularbiology, Institut für Genbiologische Forschung Berlin GmbH

• 1987 – 1993 Study of Biology, Universität Kaiserslautern and Universität Hamburg

PUBLICATIONS

A Pronounced Inflammatory Activity Characterizes the Early Fracture Healing Phase in Immunologically Restricted Patients.

International journal of molecular sciences Mar, 2017 | Pubmed ID: 28282868

Immunology Guides Skeletal Muscle Regeneration.

International journal of molecular sciences Mar, 2018 | Pubmed ID: 29534011

Treatment of osteochondral defects: chondrointegration of metal implants improves after hydroxyapatite coating.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA Mar, 2019 | Pubmed ID: 30879107

The multifaceted roles of macrophages in bone regeneration: A story of polarization, activation and time.

Acta biomaterialia Oct, 2021 | Pubmed ID: 33974949

MIF does only marginally enhance the pro-regenerative capacities of DFO in a mouse-osteotomy-model of compromised bone healing conditions.

Bone Jan, 2022 | Pubmed ID: 34743042

Editorial: Recent Advances in Basic and Translational Osteoimmunology.

Frontiers in immunology , 2021 | Pubmed ID: 34868088

Local immune cell contributions to fracture healing in aged individuals - A novel role for interleukin 22.

Experimental & molecular medicine Aug, 2022 | Pubmed ID: 36028760

Biomechanical Comparison of WE43-Based Magnesium vs. Titanium Miniplates in a Mandible Fracture Model in Sheep.

Materials (Basel, Switzerland) Dec, 2022 | Pubmed ID: 36614440

The decisive early phase of bone regeneration.

Nature reviews. Rheumatology Feb, 2023 | Pubmed ID: 36624263

The enhancer landscape predetermines the skeletal regeneration capacity of stromal cells.

Science translational medicine Mar, 2023 | Pubmed ID: 36947595

Uncovering the unique characteristics of the mandible to improve clinical approaches to mandibular regeneration.

Frontiers in physiology , 2023 | Pubmed ID: 37008011

Hydrogels with stiffness-degradation spatial patterns control anisotropic 3D cell response.

Biomaterials advances Aug, 2023 | Pubmed ID: 37167748

Patients ' perspectives on bone replacement materials in a German university hospital setting.

Biomedical engineering online Aug, 2023 | Pubmed ID: 37641065

External Mechanical Stability Regulates Hematoma Vascularization in Bone Healing Rather than Endothelial YAP/TAZ Mechanotransduction.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) Apr, 2024 | Pubmed ID: 38273642

Editorial: Interdependencies and interfaces in bone regeneration - the immune status at its core.

Frontiers in immunology , 2024 | Pubmed ID: 38524126

INSTITUTIONS

Humboldt-Universität zu Berlin

Berlin Institute of Health at Charité - Universitätsmedizin Berlin

JOVE ARTICLES

An Advanced Murine Model for Nonalcoholic Steatohepatitis in Association with Type 2 Diabetes

Julia Sbierski-Kind^1,2,3,4,

Katharina Schmidt-Bleek^3,6,

Mathias Streitz^3,5,

Jonas Kath^3,5,

Joachim Spranger^*,1,2,4,

Hans-Dieter Volk^*,2,3,5

¹Department of Endocrinology & Metabolism Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin,

², Berlin Institute of Health (BIH),

³Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin,

⁴, DZHK (German Centre for Cardiovascular Research),

⁵Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin,

⁶Julius Wolff Institute (JWI) and Center for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin

Immunology and Infection

Stabilizing a Femur Osteotomy with a Plate Fixation in Ambystoma mexicanum

Anastasia Polikarpova¹,

Christian Bucher²,

Agnes Ellinghaus^2,3,

Helena Okulski¹,

Georg Duda²,

Katharina Schmidt-Bleek^2,3,

Elly Margaret Tanaka¹

¹, Research Institute of Molecular Pathology,

²Julius Wolff Institute for Biomechanics and Musculoskeletal Regeneration, Berlin Institute of Health at Charité - Universitätsmedizin Berlin,

³Berlin Institute of Health Centre for Regenerative Therapies, Berlin Institute of Health at Charité - Universitätsmedizin Berlin

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