William M. Old

Improving reproducibility and sensitivity in identifying human proteins by shotgun proteomics.

Comparison of label-free methods for quantifying human proteins by shotgun proteomics.

Improved validation of peptide MS/MS assignments using spectral intensity prediction.

Achieving in-depth proteomics profiling by mass spectrometry.

Mps1 activation loop autophosphorylation enhances kinase activity.

Mapping protein post-translational modifications with mass spectrometry.

A simulated MS/MS library for spectrum-to-spectrum searching in large scale identification of proteins.

Budding yeast centrosome duplication requires stabilization of Spc29 via Mps1-mediated phosphorylation.

Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma.

Quantifying the impact of chimera MS/MS spectra on peptide identification in large-scale proteomics studies.

Spectrum-to-spectrum searching using a proteome-wide spectral library.

IsoformResolver: A peptide-centric algorithm for protein inference.

The non-coding B2 RNA binds to the DNA cleft and active-site region of RNA polymerase II.

Identification of global ferredoxin interaction networks in Chlamydomonas reinhardtii.

Development of substrate-selective probes for affinity pulldown of histone demethylases.

Licensing of yeast centrosome duplication requires phosphoregulation of sfi1.

Gas-phase acidities of nitrated azoles as determined by the extended kinetic method and computations.

Identification of a family of fatty-acid-speciated sonic hedgehog proteins, whose members display differential biological properties.

A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells.

Large-Scale Examination of Factors Influencing Phosphopeptide Neutral Loss during Collision Induced Dissociation.

Centromere protein F includes two sites that couple efficiently to depolymerizing microtubules.

Erratum to: Large-Scale Examination of Factors Influencing Phosphopeptide Neutral Loss During Collision Induced Dissociation.

Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics.

A Synonymous Mutation Upstream of the Gene Encoding a Weak-Link Enzyme Causes an Ultrasensitive Response in Growth Rate.

Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications.

Identification of the primary peptide contaminant that inhibits fibrillation and toxicity in synthetic amyloid-β42.

Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells.

Dengue viruses cleave STING in humans but not in nonhuman primates, their presumed natural reservoir.

Synonymous mutations make dramatic contributions to fitness when growth is limited by a weak-link enzyme.

A Novel Class of ER Membrane Proteins Regulates ER-Associated Endosome Fission.

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.

Temporal Metabolite, Ion, and Enzyme Activity Profiling Using Fluorescence Microscopy and Genetically Encoded Biosensors.

Hidden resources in the genome restore PLP synthesis and robust growth after deletion of the essential gene .