Xavier Alvarez

High frequency of virus-specific B lymphocytes in germinal centers of simian-human immunodeficiency virus-infected rhesus monkeys.

Multiple endocytic trafficking pathways of MHC class I molecules induced by a Herpesvirus protein.

Enhanced expression of proinflammatory cytokines in the central nervous system is associated with neuroinvasion by simian immunodeficiency virus and the development of encephalitis.

Proliferating cellular nuclear antigen expression as a marker of perivascular macrophages in simian immunodeficiency virus encephalitis.

Both mucosal and systemic routes of immunization with the live, attenuated NYVAC/simian immunodeficiency virus SIV(gpe) recombinant vaccine result in gag-specific CD8(+) T-cell responses in mucosal tissues of macaques.

Distribution and immunophenotype of DC-SIGN-expressing cells in SIV-infected and uninfected macaques.

Characterization of an in vitro rhesus macaque blood-brain barrier.

Plasma membrane topology of syncytial domains of herpes simplex virus type 1 glycoprotein K (gK): the UL20 protein enables cell surface localization of gK but not gK-mediated cell-to-cell fusion.

Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity.

Pathogenesis of Lyme neuroborreliosis: Borrelia burgdorferi lipoproteins induce both proliferation and apoptosis in rhesus monkey astrocytes.

Monocyte/macrophage traffic in HIV and SIV encephalitis.

Overexpression of gK in gK-transformed cells collapses the Golgi apparatus into the endoplasmic reticulum inhibiting virion egress, glycoprotein transport, and virus-induced cell fusion.

Methionine aminopeptidase 2 expression in microsporidia.

Functional simian immunodeficiency virus Gag-specific CD8+ intraepithelial lymphocytes in the mucosae of SIVmac251- or simian-human immunodeficiency virus KU2-infected macaques.

Evidence for a rhesus monkey model of asymptomatic tuberculosis.

Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer.

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival.

Direct inoculation of simian immunodeficiency virus from sooty mangabeys in black mangabeys (Lophocebus aterrimus): first evidence of AIDS in a heterologous African species and different pathologic outcomes of experimental infection.

SIV-induced activation of the blood-brain barrier requires cell-associated virus and is not restricted to endothelial cell activation.

Cell tropism of simian immunodeficiency virus in culture is not predictive of in vivo tropism or pathogenesis.

Visualizing cytokine-secreting cells in situ in the rhesus macaque model of chronic gut inflammation.

CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers.

Superoxide anion production in the rat penis impairs erectile function in diabetes: influence of in vivo extracellular superoxide dismutase gene therapy.

Nuclear and cytoplasmic localization of interferon-tau in in vitro-produced bovine blastocysts.

CD163 identifies perivascular macrophages in normal and viral encephalitic brains and potential precursors to perivascular macrophages in blood.

B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma.

Massive infection and loss of CD4+ T cells occurs in the intestinal tract of neonatal rhesus macaques in acute SIV infection.

Fluorescence in situ hybridization using an old world monkey Y chromosome specific probe combined with immunofluorescence staining on rhesus monkey tissues.

A decline in CCL3-5 chemokine gene expression during primary simian-human immunodeficiency virus infection.

Gastrointestinal disease in simian immunodeficiency virus-infected rhesus macaques is characterized by proinflammatory dysregulation of the interleukin-6-Janus kinase/signal transducer and activator of transcription3 pathway.

Clinical and immunopathologic alterations in rhesus macaques affected with globoid cell leukodystrophy.

CD163, a marker of perivascular macrophages, is up-regulated by microglia in simian immunodeficiency virus encephalitis after haptoglobin-hemoglobin complex stimulation and is suggestive of breakdown of the blood-brain barrier.

Differential cross-reactivity of monoclonal antibody OPD4 (anti-CD45RO) in macaques.

CCAAT/enhancer binding protein beta is a major mediator of inflammation and viral replication in the gastrointestinal tract of simian immunodeficiency virus-infected rhesus macaques.

The failure of immune response evasion by linear plasmid 28-1-deficient Borrelia burgdorferi is attributable to persistent expression of an outer surface protein.

Toll-like receptors: insights into their possible role in the pathogenesis of lyme neuroborreliosis.

Live Borrelia burgdorferi spirochetes elicit inflammatory mediators from human monocytes via the Toll-like receptor signaling pathway.

Efficacy of nonablative laser treatment for rhytids: a controlled study with objective evaluation via clinical, profilometric, and computer assessments.

Genetically modified CD34+ hematopoietic stem cells contribute to turnover of brain perivascular macrophages in long-term repopulated primates.

The level of monocyte turnover predicts disease progression in the macaque model of AIDS.

Association of FAK activation with lentivirus-induced disruption of blood-brain barrier tight junction-associated ZO-1 protein organization.

Genetic requirements for the survival of tubercle bacilli in primates.

Visualization of transepithelial passage of the immunogenic 33-residue peptide from alpha-2 gliadin in gluten-sensitive macaques.

Increased monocyte turnover from bone marrow correlates with severity of SIV encephalitis and CD163 levels in plasma.

Neurokinin-1 receptor (NK1-R) expression in the brains of SIV-infected rhesus macaques: implications for substance P in NK1-R immune cell trafficking into the CNS.

Simian immunodeficiency virus selectively infects proliferating CD4+ T cells in neonatal rhesus macaques.

Transcriptional reprogramming in nonhuman primate (rhesus macaque) tuberculosis granulomas.

Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication.

SH2 modified STAT1 induces HLA-I expression and improves IFN-γ signaling in IFN-α resistant HCV replicon cells.

Treatment of leg veins with combined pulsed dye and Nd:YAG lasers: 60 patients assessed at 6 months.

Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression.

Mesenchymal-Lineage Stem Cells Have Pronounced Anti-Inflammatory Effects in the Twitcher Mouse Model of Krabbe's Disease.

Transient neutropenia after granulocyte-colony stimulating factor administration is associated with neutrophil accumulation in pulmonary vasculature.

Compensatory changes in the cytoplasmic tail of gp41 confer resistance to tetherin/BST-2 in a pathogenic nef-deleted SIV.

Mesenchymal lineage stem cells have pronounced anti-inflammatory effects in the twitcher mouse model of Krabbe's disease.

Epithelial cells lining salivary gland ducts are early target cells of severe acute respiratory syndrome coronavirus infection in the upper respiratory tracts of rhesus macaques.

Recently infiltrating MAC387(+) monocytes/macrophages a third macrophage population involved in SIV and HIV encephalitic lesion formation.

Significant genetic heterogeneity of the SIVmac251 viral swarm derived from different sources.

Near-infrared tissue oximetry and digital image analysis: quantification of renal ischaemia in real time during partial nephrectomy.

A quantitative and statistically robust method for the determination of xylem conduit spatial distribution.

Distinct expression patterns of CD69 in mucosal and systemic lymphoid tissues in primary SIV infection of rhesus macaques.

The stress-response factor SigH modulates the interaction between Mycobacterium tuberculosis and host phagocytes.

Efficient Transmission and Persistence of Low Frequency SIVmac251 Variants in CD8-depleted Rhesus Macaques with Different Neuropathology.