Adam Smith
Department of Chemistry
University of Akron
Adam Smith is an Associate Professor in the Department of Chemical Engineering at the University of Mississippi in Oxford, MS. He received a B.S. and M.S. in Chemical Engineering from the University of Mississippi and a Ph.D. in Polymer Science and Engineering from the University of Southern Mississippi.
During Dr. Smith’s training he developed a focus on utilizing controlled radical polymerization techniques to synthesize block copolymers for applications in drug and gene delivery. During his doctoral studies in Charles McCormick’s lab at the University of Southern Mississippi he utilized reversible addition-fragmentation chain transfer (RAFT) polymerization for the synthesis of functional block copolymers and studied their stimuli-responsive self-assembly and shell cross-linking for drug delivery applications. His postdoctoral studies at Virginia Tech focused on the development of block copolymers gene delivery vehicles using RAFT polymerization. In the groups of Theresa Reineke and Timothy Long, he synthesized novel carbohydrate- and phosphonium-based diblock copolymers to form colloidally stable pDNA and siRNA delivery vehicles.
Time-resolved fluorescence spectroscopy measures clustering and mobility of a G protein-coupled receptor opsin in live cell membranes.
Journal of the American Chemical Society Jun, 2014 | Pubmed ID: 24831851
Tuning the mobility coupling of quaternized polyvinylpyridine and anionic phospholipids in supported lipid bilayers.
Langmuir : the ACS journal of surfaces and colloids Feb, 2015 | Pubmed ID: 25599116
Detection of rhodopsin dimerization in situ by PIE-FCCS, a time-resolved fluorescence spectroscopy.
Methods in molecular biology (Clifton, N.J.) , 2015 | Pubmed ID: 25697526
Class A Plexins Are Organized as Preformed Inactive Dimers on the Cell Surface.
Biophysical journal Nov, 2015 | Pubmed ID: 26536270
Dynamic Organization of Myristoylated Src in the Live Cell Plasma Membrane.
The journal of physical chemistry. B Jan, 2016 | Pubmed ID: 26771210
Molecular basis for multimerization in the activation of the epidermal growth factor receptor.
eLife 03, 2016 | Pubmed ID: 27017828
A G Protein-Coupled Receptor Dimerization Interface in Human Cone Opsins.
Biochemistry Jan, 2017 | Pubmed ID: 28045251
A role of the SAM domain in EphA2 receptor activation.
Scientific reports 03, 2017 | Pubmed ID: 28338017
Protein Trapping in Plasmonic Nanoslit and Nanoledge Cavities: The Behavior and Sensing.
Analytical chemistry 05, 2017 | Pubmed ID: 28418634
Quantifying membrane protein oligomerization with fluorescence cross-correlation spectroscopy.
Methods (San Diego, Calif.) 05, 2018 | Pubmed ID: 29448037
The Retinitis Pigmentosa-Linked Mutations in Transmembrane Helix 5 of Rhodopsin Disrupt Cellular Trafficking Regardless of Oligomerization State.
Biochemistry 09, 2018 | Pubmed ID: 30085663
A novel pH-dependent membrane peptide that binds to EphA2 and inhibits cell migration.
eLife 09, 2018 | Pubmed ID: 30222105
Discoidin domain receptors: Micro insights into macro assemblies.
Biochimica et biophysica acta. Molecular cell research 11, 2019 | Pubmed ID: 31229648
Quantifying Lipid Mobility and Peptide Binding for Gram-Negative and Gram-Positive Model Supported Lipid Bilayers.
The journal of physical chemistry. B 12, 2019 | Pubmed ID: 31729230
Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane.
eLife Jan, 2020 | Pubmed ID: 31922487
Resolving Membrane Protein-Protein Interactions in Live Cells with Pulsed Interleaved Excitation Fluorescence Cross-Correlation Spectroscopy.
Accounts of chemical research 04, 2020 | Pubmed ID: 32227891
Covalently Immobilizing Interferon-γ Drives Filopodia Production through Specific Receptor-Ligand Interactions Independently of Canonical Downstream Signaling.
Bioconjugate chemistry May, 2020 | Pubmed ID: 32329609
JoVE Hakkında
Telif Hakkı © 2020 MyJove Corporation. Tüm hakları saklıdır