Joanna M. Bridger

Mammalian artificial chromosomes: modern day feats of engineering--Isambard Kingdom Brunel style.

Progeria Research Day at Brunel University.

Chromobility: the rapid movement of chromosomes in interphase nuclei.

The non-random repositioning of whole chromosomes and individual gene loci in interphase nuclei and its relevance in disease, infection, aging, and cancer.

Schistosomes and snails: a molecular encounter.

Rapamycin reduces fibroblast proliferation without causing quiescence and induces STAT5A/B-mediated cytokine production.

Epigenetic modulation, stress and plasticity in susceptibility of the snail host, Biomphalaria glabrata, to Schistosoma mansoni infection.

A structured environment helps to regulate nuclear architecture in breast epithelial cells.

Visualizing the Spatial Relationship of the Genome with the Nuclear Envelope Using Fluorescence In Situ Hybridization.

Whole genome analysis of a schistosomiasis-transmitting freshwater snail.

Farnesyltransferase inhibitor and rapamycin correct aberrant genome organisation and decrease DNA damage respectively, in Hutchinson-Gilford progeria syndrome fibroblasts.

The snail Biomphalaria glabrata as a model to interrogate the molecular basis of complex human diseases.

Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform.

The Genomic Health of Human Pluripotent Stem Cells: Genomic Instability and the Consequences on Nuclear Organization.

Deletions of Chromosome 7q Affect Nuclear Organization and Gene Expression in Hematological Disorders.

Presence and distribution of progerin in HGPS cells is ameliorated by drugs that impact on the mevalonate and mTOR pathways.

The Nuclear Lamina: Protein Accumulation and Disease.