Wolfram Goessling

Merkel cell carcinoma.

Increased liver chemistry in an asymptomatic patient.

Position Is Destiny: Metabolism and Cell Identity.

New waves of discovery: modeling cancer in zebrafish.

Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors.

Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis.

Transparent adult zebrafish as a tool for in vivo transplantation analysis.

APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development.

Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease.

Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration.

Topoisomerase II alpha is required for embryonic development and liver regeneration in zebrafish.

Hematopoietic stem cell development is dependent on blood flow.

PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.

Previews. NOTCHing an arrow at cord blood: translating stem cell knowledge into clinical practice.

The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.

Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models.

Endoderm specification, liver development, and regeneration.

Deficiency of the cytoskeletal protein SPECC1L leads to oblique facial clefting.

Genetic association for renal traits among participants of African ancestry reveals new loci for renal function.

Hematopoietic stem cell development: using the zebrafish to identify the signaling networks and physical forces regulating hematopoiesis.

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.

Genome-wide association and functional follow-up reveals new loci for kidney function.

Mutation mapping and identification by whole-genome sequencing.

SCF(β-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2.

Rargb regulates organ laterality in a zebrafish model of right atrial isomerism.

β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.

Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo.

Identification of small molecules for human hepatocyte expansion and iPS differentiation.

Functional validation of GWAS gene candidates for abnormal liver function during zebrafish liver development.

Rapid identification of kidney cyst mutations by whole exome sequencing in zebrafish.

S-nitrosothiol signaling regulates liver development and improves outcome following toxic liver injury.

Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth.

Regenerative biology: Take the brakes off for liver repair.

Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche.

Repairing quite swimmingly: advances in regenerative medicine using zebrafish.

Genome-wide association study of kidney function decline in individuals of European descent.

ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning.

The lure of zebrafish in liver research: regulation of hepatic growth in development and regeneration.

Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity.

Zebrafish: an important tool for liver disease research.

Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation.

Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.

Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis.

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.

Cannabinoid receptor signaling regulates liver development and metabolism.

Hypoxia as a therapy for mitochondrial disease.

EnaBILEing Growth in the Fetal Liver.

Baiting for Cancer: Using the Zebrafish as a Model in Liver and Pancreatic Cancer.

Mitochondrial dysfunction remodels one-carbon metabolism in human cells.

Nature and nurture: Environmental toxins and biliary atresia.

The Central Nervous System Regulates Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling.

Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth.

Iterative use of nuclear receptor Nr5a2 regulates multiple stages of liver and pancreas development.

Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis.

Developmental Vitamin D Availability Impacts Hematopoietic Stem Cell Production.

Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation.

and Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.

Haematopoietic stem cells show their true colours.

WNTing no RASt for hepatocellular carcinoma.

The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development.

An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery.

Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth.

Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes.

There Is Something Fishy About Liver Cancer: Zebrafish Models of Hepatocellular Carcinoma.

Tfap2a is a novel gatekeeper of nephron differentiation during kidney development.

Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer.

A quantitative single-cell assay for retrograde membrane traffic enables rapid detection of defects in cellular organization.

Macrophages in Zebrafish Models of Liver Diseases.

A phase 2 clinical trial of the heat shock protein 90 (HSP 90) inhibitor ganetespib in patients with refractory advanced esophagogastric cancer.

YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow.

Estrogen Acts Through Estrogen Receptor 2b to Regulate Hepatobiliary Fate During Vertebrate Development.

Synthetic CRISPR/Cas9 reagents facilitate genome editing and homology directed repair.

Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood.

Hepatobiliary Differentiation: Principles from Embryonic Liver Development.

Imaging Mass Spectrometry Reveals Tumor Metabolic Heterogeneity.

Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production.

Learning During and From a Crisis: The Student-Led Development of a COVID-19 Curriculum.

The cationic amino acid exporter Slc7a7 is induced and vital in zebrafish tissue macrophages with sustained efferocytic activity.

Functional compensation precedes recovery of tissue mass following acute liver injury.

Quantitative intravital imaging in zebrafish reveals dynamics of physiological-stress-induced mitophagy.