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Department of Clinical Genetics
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Fine mapping of the alpha-T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer's disease pedigrees.
Human molecular genetics Dec, 2003 | Pubmed ID: 14559775
Assessment of a DJ-1 (PARK7) polymorphism in Finnish PD.
Neurology Jun, 2004 | Pubmed ID: 15210917
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease.
Neuron Nov, 2004 | Pubmed ID: 15541308
Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene.
Human molecular genetics Feb, 2005 | Pubmed ID: 15615772
Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease.
Lancet Jan 29-Feb 4, 2005 | Pubmed ID: 15680455
A common LRRK2 mutation in idiopathic Parkinson's disease.
Lancet Jan 29-Feb 4, 2005 | Pubmed ID: 15680457
Clinical and positron emission tomography of Parkinson's disease caused by LRRK2.
Annals of neurology Mar, 2005 | Pubmed ID: 15732108
Molecular genetic pathways in Parkinson's disease: a review.
Clinical science (London, England : 1979) Oct, 2005 | Pubmed ID: 16171459
Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data.
Brain : a journal of neurology Dec, 2005 | Pubmed ID: 16272164
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin.
Neurobiology of disease Aug, 2006 | Pubmed ID: 16750377
Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD.
BMC neurology , 2006 | Pubmed ID: 17166276
The R1441C mutation of LRRK2 disrupts GTP hydrolysis.
Biochemical and biophysical research communications Jun, 2007 | Pubmed ID: 17442267
Comprehensive screening of a North American Parkinson's disease cohort for LRRK2 mutation.
Neuro-degenerative diseases , 2007 | Pubmed ID: 17622782
The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation.
The Journal of biological chemistry Jun, 2008 | Pubmed ID: 18397888
From single genes to gene networks: high-throughput-high-content screening for neurological disease.
Neuron Oct, 2010 | Pubmed ID: 20955929
SFRS7-mediated splicing of tau exon 10 is directly regulated by STOX1A in glial cells.
PloS one , 2011 | Pubmed ID: 21755018
The complete automation of cell culture: improvements for high-throughput and high-content screening.
Journal of biomolecular screening Sep, 2011 | Pubmed ID: 21775700
VU University medical center
Shushant Jain1,
Ronald E. van Kesteren2,
Peter Heutink1
1Department of Clinical Genetics, VU University Medical Center,
2Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam
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