Eric J. Toone

Stereospecific Preparation of the N-Terminal Amino Acid Moiety of Nikkomycins K(X) and K(Z) via a Multiple Enzyme Synthesis.

Cloning, isolation and characterization of the Thermotoga maritima KDPG aldolase.

The cluster glycoside effect.

The decomposition of thionitrites.

Nitroxyl disulfides, novel intermediates in transnitrosation reactions.

Additivity and the physical basis of multivalency effects: a thermodynamic investigation of the calcium EDTA interaction.

Solid-phase synthesis for the identification of high-affinity bivalent lectin ligands.

Calorimetric evaluation of protein-carbohydrate affinities.

A bacterial selection for the directed evolution of pyruvate aldolases.

A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells.

Nitrosonium-catalyzed decomposition of s-nitrosothiols in solution: a theoretical and experimental study.

C-nitroso compounds: synthesis, physicochemical properties and biological activities.

Mechanism of the Class I KDPG aldolase.

Binding of warfarin influences the acid-base equilibrium of H242 in sudlow site I of human serum albumin.

A stochastic, cantilever approach to the evaluation of solution phase thermodynamic quantities.

Pyruvate aldolases in chiral carbon-carbon bond formation.

Biocatalytic microcontact printing.

Inkless microcontact printing on self-assembled monolayers of fmoc-protected aminothiols.

Mutagenesis of the phosphate-binding pocket of KDPG aldolase enhances selectivity for hydrophobic substrates.

Characterization and crystal structure of Escherichia coli KDPGal aldolase.

Advances in enzymology and related areas of molecular biology. Preface.

C-nitroso donors of nitric oxide.

Eyedrops containing SA9000 prodrugs result in sustained reductions in intraocular pressure in rabbits.

In situ growth of a stoichiometric PEG-like conjugate at a protein's N-terminus with significantly improved pharmacokinetics.

A single step purification for autolytic zinc proteinases.

Inkless microcontact printing on SAMs of Boc- and TBS-protected thiols.

Catalytic microcontact printing on chemically functionalized H-terminated silicon.

Identification and inhibitory properties of a novel Ca(2+)/calmodulin antagonist.

Thermodynamic characterization of the binding interaction between the histone demethylase LSD1/KDM1 and CoREST.

Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.

Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold.

Patterning NHS-terminated SAMs on germanium.

Soft-lithographic approach to functionalization and nanopatterning oxide-free silicon.

Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis.

Bacterial infection remains a leading cause of death in both Western and developing world. Preface.

A multidisciplinary approach to probing enthalpy-entropy compensation and the interfacial mobility model.

Directed evolution of a pyruvate aldolase to recognize a long chain acyl substrate.

Derivatives of plant phenolic compound affect the type III secretion system of Pseudomonas aeruginosa via a GacS-GacA two-component signal transduction system.

Advances in enzymology and related areas of molecular biology. Preface.

Improving upon Nature: Active site remodeling produces highly efficient aldolase activity towards hydrophobic electrophilic substrates.