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Department of Molecular Physiology
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Pharyngeal arch artery defects and lethal malformations of the aortic arch and its branches in mice deficient for the Hrt1/Hey1 transcription factor.
Mechanisms of development Feb, 2016 | Pubmed ID: 26577899
Notch and Hippo signaling converge on Strawberry Notch 1 (Sbno1) to synergistically activate Cdx2 during specification of the trophectoderm.
Scientific reports 04, 2017 | Pubmed ID: 28401892
Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling.
Development (Cambridge, England) 07, 2017 | Pubmed ID: 28576770
Serum/glucocorticoid-regulated kinase 1 as a novel transcriptional target of bone morphogenetic protein-ALK1 receptor signaling in vascular endothelial cells.
Angiogenesis Feb, 2018 | Pubmed ID: 29478089
ETV2-TET1/TET2 Complexes Induce Endothelial Cell-Specific Robo4 Expression via Promoter Demethylation.
Scientific reports 04, 2018 | Pubmed ID: 29618782
Effective gene silencing activity of prodrug-type 2'-O-methyldithiomethyl siRNA compared with non-prodrug-type 2'-O-methyl siRNA.
Bioorganic & medicinal chemistry letters 07, 2018 | Pubmed ID: 29764744
Shootins mediate collective cell migration and organogenesis of the zebrafish posterior lateral line system.
Scientific reports 08, 2019 | Pubmed ID: 31434971
Maternal administration of tadalafil improves fetal ventricular systolic function in a Hey2 knockout mouse model of fetal heart failure.
International journal of cardiology 03, 2020 | Pubmed ID: 31924399
Expression of Hey2 transcription factor in the early embryonic ventricles is controlled through a distal enhancer by Tbx20 and Gata transcription factors.
Developmental biology 05, 2020 | Pubmed ID: 32035085
A role of Hey2 transcription factor for right ventricle development through regulation of Tbx2-Mycn pathway during cardiac morphogenesis.
Development, growth & differentiation Jan, 2021 | Pubmed ID: 33410138
Importance of endothelial Hey1 expression for thoracic great vessel development and its distal enhancer for Notch-dependent endothelial transcription.
The Journal of biological chemistry 12, 2020 | Pubmed ID: 33454003
Tmem100-BAC-EGFP mice to selectively mark and purify embryonic endothelial cells of large caliber arteries in mid-gestational vascular formation.
Genesis (New York, N.Y. : 2000) Apr, 2021 | Pubmed ID: 33651473
ETS-dependent enhancers for endothelial-specific expression of serum/glucocorticoid-regulated kinase 1 during mouse embryo development.
Genes to cells : devoted to molecular & cellular mechanisms Aug, 2021 | Pubmed ID: 34081835
National Cerebral and Cardiovascular Center Research Institute
Daiki Seya1,
Yuqing Xu2,3,
Toshifumi Mukunoki4,
Kenichi Tsujita3,
Osamu Nakagawa1,
Yuichiro Arima1,2,3,4
1Department of Molecular Physiology, National Cerebral and Cardiovascular Center Research Institute,
2International Research Center for Medical Sciences (IRCMS), Kumamoto University,
3Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University,
4X-Earth Center, Faculty of Advanced Science and Technology, Kumamoto University
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