Ricardo E Dolmetsch

CREB transcriptional activity in neurons is regulated by multiple, calcium-specific phosphorylation events.

Time-lapse imaging of a dynamic phosphorylation-dependent protein-protein interaction in mammalian cells.

Molecular mechanisms of autism: a possible role for Ca2+ signaling.

Calcium channels light up.

The tumor suppressor eIF3e mediates calcium-dependent internalization of the L-type calcium channel CaV1.2.

TrpC3 regulates hypertrophy-associated gene expression without affecting myocyte beating or cell size.

STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1.

STIM1 and calmodulin interact with Orai1 to induce Ca2+-dependent inactivation of CRAC channels.

Induction of protein-protein interactions in live cells using light.

PIKfyve regulates CaV1.2 degradation and prevents excitotoxic cell death.

Using light to control signaling cascades in live neurons.

Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome.

LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress.

MicroRNA-mediated conversion of human fibroblasts to neurons.

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome.