Chase L. Beisel

An enhanced assay to characterize anti-CRISPR proteins using a cell-free transcription-translation system.

Barriers to genome editing with CRISPR in bacteria.

Modular one-pot assembly of CRISPR arrays enables library generation and reveals factors influencing crRNA biogenesis.

CRATES: A one-step assembly method for Class 2 CRISPR arrays.

Methods for characterizing, applying, and teaching CRISPR-Cas systems.

Your Base Editor Might Be Flirting with Single (Stranded) DNA: Faithful On-Target CRISPR Base Editing without Promiscuous Deamination.

CRISPR technologies and the search for the PAM-free nuclease.

Noncanonical crRNAs derived from host transcripts enable multiplexable RNA detection by Cas9.

CRISPR transposons on the move.

The tracrRNA in CRISPR Biology and Technologies.

Rapidly Characterizing CRISPR-Cas13 Nucleases Using Cell-Free Transcription-Translation Systems.

Illuminating the path to DNA repair.

A TXTL-Based Assay to Rapidly Identify PAMs for CRISPR-Cas Systems with Multi-Protein Effector Complexes.

Rapid cell-free characterization of multi-subunit CRISPR effectors and transposons.

Spacer prioritization in CRISPR-Cas9 immunity is enabled by the leader RNA.

Genome Editing with Cas9 in Lactobacilli.

Anti-CRISPR prediction using deep learning reveals an inhibitor of Cas13b nucleases.

Reprogramming TracrRNAs for Multiplexed RNA Detection.

A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13.