Gerrit Borchard

Stimulation of human macrophages (THP-1) using Toll-like receptor-2 (TLR-2) agonist decorated nanocarriers.

Noncovalent pegylation by dansyl-poly(ethylene glycol)s as a new means against aggregation of salmon calcitonin.

Tryptophan-mPEGs: novel excipients that stabilize salmon calcitonin against aggregation by non-covalent PEGylation.

Toll-like receptor-7 agonist decoration enhances the adjuvanticity of chitosan-DNA nanoparticles.

Noncovalent PEGylation: different effects of dansyl-, L-tryptophan-, phenylbutylamino-, benzyl- and cholesteryl-PEGs on the aggregation of salmon calcitonin and lysozyme.

The School of Pharmacy Geneva-Lausanne (EPGL) - the first ten years.

In vitro evaluation of an RGD-functionalized chitosan derivative for enhanced cell adhesion.

Nanoparticle iron medicinal products - Requirements for approval of intended copies of non-biological complex drugs (NBCD) and the importance of clinical comparative studies.

Preparation and evaluation of nanoparticles for directed tissue engineering.

Validation of a new 96-well plate spectrophotometric method for the quantification of compound 48/80 associated with particles.

Recent advances in mucosal immunization using virus-like particles.

Multifunctional PLGA-based nanoparticles encapsulating simultaneously hydrophilic antigen and hydrophobic immunomodulator for mucosal immunization.

Fate of TLR-1/TLR-2 agonist functionalised pDNA nanoparticles upon deposition at the human bronchial epithelium in vitro.

Drug-eluting beads loaded with antiangiogenic agents for chemoembolization: in vitro sunitinib loading and release and in vivo pharmacokinetics in an animal model.

Toll-like receptor 2 regulates the barrier function of human bronchial epithelial monolayers through atypical protein kinase C zeta, and an increase in expression of claudin-1.

Sunitinib-eluting beads for chemoembolization: methods for in vitro evaluation of drug release.

Establishment and first characterization of a sublingual epithelial and immune cell co-culture model.

Novel Layer-by-Layer Deposition Technique for the Preparation of Double-Chambered Nanoparticle Formulations.

Sustained protein release from hydrogel microparticles using layer-by-layer (LbL) technology.

Noncovalent PEGylation, An Innovative Subchapter in the Field of Protein Modification.

Chitosan as a starting material for wound healing applications.

Characterization of pDNA-TMC Nanoparticle Interaction and Stability.

Arming embolic beads with anti-VEGF antibodies and controlling their release using LbL technology.

Peptide-decorated chitosan derivatives enhance fibroblast adhesion and proliferation in wound healing.

Immune response elicited by an intranasally delivered HBsAg low-dose adsorbed to poly-ε-caprolactone based nanoparticles.

Non-covalent modification of granulocyte-colony stimulating factor (G-CSF) by coiled-coil technology.

Ag85A DNA Vaccine Delivery by Nanoparticles: Influence of the Formulation Characteristics on Immune Responses.

Nanocarriers for DNA Vaccines: Co-Delivery of TLR-9 and NLR-2 Ligands Leads to Synergistic Enhancement of Proinflammatory Cytokine Release.

Equivalence of complex drug products: advances in and challenges for current regulatory frameworks.

Drug-eluting embolic microspheres for local drug delivery - State of the art.

Poly-ϵ-caprolactone/chitosan nanoparticles provide strong adjuvant effect for hepatitis B antigen.

Free energy landscape of siRNA-polycation complexation: Elucidating the effect of molecular geometry, polymer flexibility, and charge neutralization.

Mapping of drug distribution in the rabbit liver tumor model by complementary fluorescence and mass spectrometry imaging.

Adjuvant Activity of Poly-ε-caprolactone/Chitosan Nanoparticles Characterized by Mast Cell Activation and IFN-γ and IL-17 Production.

Iron sucrose: assessing the similarity between the originator drug and its intended copies.

Cellular Interaction and Tumoral Penetration Properties of Cyclodextrin Nanoparticles on 3D Breast Tumor Model.

A robust and easily reproducible protocol for the determination of size and size distribution of iron sucrose using dynamic light scattering.

Hydrogels in three-dimensional dendritic cell (MUTZ-3) culture as a scaffold to mimic human immuno competent subcutaneous tissue.

In vitro models for immunogenicity prediction of therapeutic proteins.

Nanomedicines: The magic bullets reaching their target?

Differences between intravenous iron products: focus on treatment of iron deficiency in chronic heart failure patients.

Nanomedicines in clinical practice: Are colloidal iron sucrose ready-to-use intravenous solutions interchangeable?

Polyelectrolyte nanocomplexes based on chitosan derivatives for wound healing application.

Impact of covalently Nile Red and covalently Rhodamine labeled fluorescent polymer micelles for the improved imaging of the respective drug delivery system.

Molecular Modeling for Nanomaterial-Biology Interactions: Opportunities, Challenges, and Perspectives.

Hazard Assessment of Polymeric Nanobiomaterials for Drug Delivery: What Can We Learn From Literature So Far.

Iron polymaltose complexes: Could we spot physicochemical differences in medicines sharing the same active pharmaceutical ingredient?

Factors influencing safety and efficacy of intravenous iron-carbohydrate nanomedicines: From production to clinical practice.

Chitosan Nanoparticles: Shedding Light on Immunotoxicity and Hemocompatibility.

How the Lack of Chitosan Characterization Precludes Implementation of the Safe-by-Design Concept.

Are Antimicrobial Peptide Dendrimers an Escape from ESKAPE?

An Update on Antimicrobial Peptides (AMPs) and Their Delivery Strategies for Wound Infections.

Short peptide sequence enhances epithelial permeability through interaction with protein kinase C.

Target specific tight junction modulators.

Wound Healing Promotion by Hyaluronic Acid: Effect of Molecular Weight on Gene Expression and In Vivo Wound Closure.

Better Pandemic Influenza Preparedness through Adjuvant Technology Transfer: Challenges and Lessons Learned.

A pragmatic regulatory approach for complex generics through the U.S. FDA 505(j) or 505(b)(2) approval pathways.

DNA Vaccine Administered by Cationic Lipoplexes or by In Vivo Electroporation Induces Comparable Antibody Responses against SARS-CoV-2 in Mice.

Synergistic effects of antimicrobial peptide dendrimer-chitosan polymer conjugates against Pseudomonas aeruginosa.

Need for Expansion of Pharmacy Education Globally for the Growing Field of Nanomedicine.

Structure-activity relationship of a peptide permeation enhancer.

Translating a Thin-Film Rehydration Method to Microfluidics for the Preparation of a SARS-CoV-2 DNA Vaccine: When Manufacturing Method Matters.

Regulatory safety evaluation of nanomedical products: key issues to refine.

Synthesis, Formulation and Characterization of Immunotherapeutic Glycosylated Dendrimer/cGAMP Complexes for CD206 Targeted Delivery to M2 Macrophages in Cold Tumors.

Characterization of the Interaction of Polymeric Micelles with siRNA: A Combined Experimental and Molecular Dynamics Study.

Impact of peptide permeation enhancer on tight junctions opening cellular mechanisms.

Characterization Challenges of Self-Assembled Polymer-SPIONs Nanoparticles: Benefits of Orthogonal Methods.

Meeting vaccine formulation challenges in an emergency setting: Towards the development of accessible vaccines.

HDACIs and TKIs combinations and their liposomal delivery for cancer treatment.

Identification of the Proteins Determining the Blood Circulation Time of Nanoparticles.