Gerrit Borchard

Section of Pharmaceutical Sciences, University of Geneva

Research Area

Medicine

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2023

Other Publications

Article	Year
Stimulation of human macrophages (THP-1) using Toll-like receptor-2 (TLR-2) agonist decorated nanocarriers. Journal of drug targeting\| PubMed ID: 19694614	2009
Noncovalent pegylation by dansyl-poly(ethylene glycol)s as a new means against aggregation of salmon calcitonin. Journal of pharmaceutical sciences\| PubMed ID: 21374604	2011
Tryptophan-mPEGs: novel excipients that stabilize salmon calcitonin against aggregation by non-covalent PEGylation. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 21703347	2011
Toll-like receptor-7 agonist decoration enhances the adjuvanticity of chitosan-DNA nanoparticles. Journal of pharmaceutical sciences\| PubMed ID: 22190381	2012
Noncovalent PEGylation: different effects of dansyl-, L-tryptophan-, phenylbutylamino-, benzyl- and cholesteryl-PEGs on the aggregation of salmon calcitonin and lysozyme. Journal of pharmaceutical sciences\| PubMed ID: 22447529	2012
The School of Pharmacy Geneva-Lausanne (EPGL) - the first ten years. Chimia\| PubMed ID: 22867535	2012
In vitro evaluation of an RGD-functionalized chitosan derivative for enhanced cell adhesion. Carbohydrate polymers\| PubMed ID: 22944407	2012
Nanoparticle iron medicinal products - Requirements for approval of intended copies of non-biological complex drugs (NBCD) and the importance of clinical comparative studies. Regulatory toxicology and pharmacology : RTP\| PubMed ID: 22951348	2012
Preparation and evaluation of nanoparticles for directed tissue engineering. International journal of pharmaceutics\| PubMed ID: 23046666	2012
Validation of a new 96-well plate spectrophotometric method for the quantification of compound 48/80 associated with particles. AAPS PharmSciTech\| PubMed ID: 23468340	2013
Recent advances in mucosal immunization using virus-like particles. Molecular pharmaceutics\| PubMed ID: 23548071	2013
Multifunctional PLGA-based nanoparticles encapsulating simultaneously hydrophilic antigen and hydrophobic immunomodulator for mucosal immunization. Molecular pharmaceutics\| PubMed ID: 23869898	2013
Fate of TLR-1/TLR-2 agonist functionalised pDNA nanoparticles upon deposition at the human bronchial epithelium in vitro. Journal of nanobiotechnology\| PubMed ID: 23964697	2013
Drug-eluting beads loaded with antiangiogenic agents for chemoembolization: in vitro sunitinib loading and release and in vivo pharmacokinetics in an animal model. Journal of vascular and interventional radiology : JVIR\| PubMed ID: 24468044	2014
Toll-like receptor 2 regulates the barrier function of human bronchial epithelial monolayers through atypical protein kinase C zeta, and an increase in expression of claudin-1. Tissue barriers\| PubMed ID: 25101232	2014
Sunitinib-eluting beads for chemoembolization: methods for in vitro evaluation of drug release. International journal of pharmaceutics\| PubMed ID: 25448554	2015
Establishment and first characterization of a sublingual epithelial and immune cell co-culture model. International journal of pharmaceutics\| PubMed ID: 25448555	2015
Novel Layer-by-Layer Deposition Technique for the Preparation of Double-Chambered Nanoparticle Formulations. Journal of pharmaceutical sciences\| PubMed ID: 26017561	2015
Sustained protein release from hydrogel microparticles using layer-by-layer (LbL) technology. Drug delivery\| PubMed ID: 26289209	2016
Noncovalent PEGylation, An Innovative Subchapter in the Field of Protein Modification. Journal of pharmaceutical sciences\| PubMed ID: 26523632	2016
Chitosan as a starting material for wound healing applications. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 26614560	2015
Characterization of pDNA-TMC Nanoparticle Interaction and Stability. Current drug delivery\| PubMed ID: 26638979	2016
Arming embolic beads with anti-VEGF antibodies and controlling their release using LbL technology. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 26780173	2016
Peptide-decorated chitosan derivatives enhance fibroblast adhesion and proliferation in wound healing. Carbohydrate polymers\| PubMed ID: 26917381	2016
Immune response elicited by an intranasally delivered HBsAg low-dose adsorbed to poly-ε-caprolactone based nanoparticles. International journal of pharmaceutics\| PubMed ID: 26976502	2016
Non-covalent modification of granulocyte-colony stimulating factor (G-CSF) by coiled-coil technology. International journal of pharmaceutics\| PubMed ID: 27363936	2016
Ag85A DNA Vaccine Delivery by Nanoparticles: Influence of the Formulation Characteristics on Immune Responses. Vaccines\| PubMed ID: 27626449	2016
Nanocarriers for DNA Vaccines: Co-Delivery of TLR-9 and NLR-2 Ligands Leads to Synergistic Enhancement of Proinflammatory Cytokine Release. Nanomaterials (Basel, Switzerland)\| PubMed ID: 28347123	2015
Equivalence of complex drug products: advances in and challenges for current regulatory frameworks. Annals of the New York Academy of Sciences\| PubMed ID: 28445611	2017
Drug-eluting embolic microspheres for local drug delivery - State of the art. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 28710006	2017
Poly-ϵ-caprolactone/chitosan nanoparticles provide strong adjuvant effect for hepatitis B antigen. Nanomedicine (London, England)\| PubMed ID: 28868964	2017
Free energy landscape of siRNA-polycation complexation: Elucidating the effect of molecular geometry, polymer flexibility, and charge neutralization. PloS one\| PubMed ID: 29088239	2017
Mapping of drug distribution in the rabbit liver tumor model by complementary fluorescence and mass spectrometry imaging. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 29101054	2018
Adjuvant Activity of Poly-ε-caprolactone/Chitosan Nanoparticles Characterized by Mast Cell Activation and IFN-γ and IL-17 Production. Molecular pharmaceutics\| PubMed ID: 29160080	2018
Iron sucrose: assessing the similarity between the originator drug and its intended copies. Annals of the New York Academy of Sciences\| PubMed ID: 29168243	2017
Cellular Interaction and Tumoral Penetration Properties of Cyclodextrin Nanoparticles on 3D Breast Tumor Model. Nanomaterials (Basel, Switzerland)\| PubMed ID: 29373490	2018
A robust and easily reproducible protocol for the determination of size and size distribution of iron sucrose using dynamic light scattering. Journal of pharmaceutical and biomedical analysis\| PubMed ID: 29414023	2018
Hydrogels in three-dimensional dendritic cell (MUTZ-3) culture as a scaffold to mimic human immuno competent subcutaneous tissue. International journal of pharmaceutics\| PubMed ID: 29698823	2018
In vitro models for immunogenicity prediction of therapeutic proteins. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 29894817	2018
Nanomedicines: The magic bullets reaching their target? European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 30465818	2019
Differences between intravenous iron products: focus on treatment of iron deficiency in chronic heart failure patients. ESC heart failure\| PubMed ID: 30694615	2019
Nanomedicines in clinical practice: Are colloidal iron sucrose ready-to-use intravenous solutions interchangeable? European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 30742979	2019
Polyelectrolyte nanocomplexes based on chitosan derivatives for wound healing application. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 31085312	2019
Impact of covalently Nile Red and covalently Rhodamine labeled fluorescent polymer micelles for the improved imaging of the respective drug delivery system. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 31336183	2019
Molecular Modeling for Nanomaterial-Biology Interactions: Opportunities, Challenges, and Perspectives. Frontiers in bioengineering and biotechnology\| PubMed ID: 31681746	2019
Hazard Assessment of Polymeric Nanobiomaterials for Drug Delivery: What Can We Learn From Literature So Far. Frontiers in bioengineering and biotechnology\| PubMed ID: 31709243	2019
Iron polymaltose complexes: Could we spot physicochemical differences in medicines sharing the same active pharmaceutical ingredient? European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 31841697	2020
Factors influencing safety and efficacy of intravenous iron-carbohydrate nanomedicines: From production to clinical practice. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 32145382	2020
Chitosan Nanoparticles: Shedding Light on Immunotoxicity and Hemocompatibility. Frontiers in bioengineering and biotechnology\| PubMed ID: 32154232	2020
How the Lack of Chitosan Characterization Precludes Implementation of the Safe-by-Design Concept. Frontiers in bioengineering and biotechnology\| PubMed ID: 32211394	2020
Are Antimicrobial Peptide Dendrimers an Escape from ESKAPE? Advances in wound care\| PubMed ID: 32320368	2020
An Update on Antimicrobial Peptides (AMPs) and Their Delivery Strategies for Wound Infections. Pharmaceutics\| PubMed ID: 32887353	2020
Short peptide sequence enhances epithelial permeability through interaction with protein kinase C. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 33582284	2021
Target specific tight junction modulators. Advanced drug delivery reviews\| PubMed ID: 33617902	2021
Wound Healing Promotion by Hyaluronic Acid: Effect of Molecular Weight on Gene Expression and In Vivo Wound Closure. Pharmaceuticals (Basel, Switzerland)\| PubMed ID: 33800588	2021
Better Pandemic Influenza Preparedness through Adjuvant Technology Transfer: Challenges and Lessons Learned. Vaccines\| PubMed ID: 34063131	2021
A pragmatic regulatory approach for complex generics through the U.S. FDA 505(j) or 505(b)(2) approval pathways. Annals of the New York Academy of Sciences\| PubMed ID: 34296458	2021
DNA Vaccine Administered by Cationic Lipoplexes or by In Vivo Electroporation Induces Comparable Antibody Responses against SARS-CoV-2 in Mice. Vaccines\| PubMed ID: 34451998	2021
Synergistic effects of antimicrobial peptide dendrimer-chitosan polymer conjugates against Pseudomonas aeruginosa. Carbohydrate polymers\| PubMed ID: 35027127	2022
Need for Expansion of Pharmacy Education Globally for the Growing Field of Nanomedicine. Pharmacy (Basel, Switzerland)\| PubMed ID: 35202067	2022
Structure-activity relationship of a peptide permeation enhancer. Tissue barriers\| PubMed ID: 35369830	2023
Translating a Thin-Film Rehydration Method to Microfluidics for the Preparation of a SARS-CoV-2 DNA Vaccine: When Manufacturing Method Matters. Pharmaceutics\| PubMed ID: 35890321	2022
Regulatory safety evaluation of nanomedical products: key issues to refine. Drug delivery and translational research\| PubMed ID: 35908133	2022
Synthesis, Formulation and Characterization of Immunotherapeutic Glycosylated Dendrimer/cGAMP Complexes for CD206 Targeted Delivery to M2 Macrophages in Cold Tumors. Pharmaceutics\| PubMed ID: 36145631	2022
Characterization of the Interaction of Polymeric Micelles with siRNA: A Combined Experimental and Molecular Dynamics Study. Polymers\| PubMed ID: 36297986	2022
Impact of peptide permeation enhancer on tight junctions opening cellular mechanisms. Biochemistry and biophysics reports\| PubMed ID: 36324528	2022
Characterization Challenges of Self-Assembled Polymer-SPIONs Nanoparticles: Benefits of Orthogonal Methods. International journal of molecular sciences\| PubMed ID: 36555765	2022
Meeting vaccine formulation challenges in an emergency setting: Towards the development of accessible vaccines. Pharmacological research\| PubMed ID: 36796463	2023
HDACIs and TKIs combinations and their liposomal delivery for cancer treatment. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 37037270	2023
Identification of the Proteins Determining the Blood Circulation Time of Nanoparticles. ACS nano\| PubMed ID: 37379064	2023